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A COMPARATIVE STUDY OF DOT AND SAT IN RURAL TERTIARY CARE HOSPITAL: A TWO YEARS RETROSPECTIVE STUDY
Directly observed therapy (DOT) of tuberculosis patients talking their drugs is supposed to improve treatment completion and outcome .we compared DOT and Self Administered therapy (SAT), in which patients on the same drug regimen are not, observed taking their pills, to assess the effect of each on the success of tuberculosis treatment. This was the two year (2010 and 2011) retrospective study of ...
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INDUCTION OF ROOTS AND IN-VITRO REGENERATION OF NOTHAPODYTES NIMMONIANA GRAHAM FROM EMBRYO CULTURES
The present study was aimed to develop the effective protocol for induction roots and in-vitro regenerated plants from embryo culture of Nothapodytes nimmoniana. Excised embryos were sterilized under the aseptic condition and cultured on L2 medium fortified with different concentration (0.5 - 3 mg/L) and the combination of auxins and cytokinins. Maximum shoot initiation was observed in BAP (2 mg/L...
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EFFECT OF TWO LEVELS FROM GINSENG AND GREEN COFFEE ON OBESE RATS
The present study aimed to investigate the effect of two levels from (green coffee, ginseng and their combination) on nutritional and biochemical status of obese rats. Forty eight male albino rats (Sprague Dawley Strain) used in this study, the rats divided into two main groups. The first main group (6 rats) fed on basal diet (as a control negative group). The second main group (42 rats) was fed e...
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POLYELECTROLYTE COMPLEXATION AND IONOTROPIC GELLATION: THE POTENTIAL NOVEL APPROACH TO DESIGN HYDROGEL PARTICULATE FOR SUSTAINED, MODULATED DRUG DELIVERY SYSTEM: A REVIEW
The interest in using natural and chemically modified polysaccharides as a part of drug development has increased in the past two decades. For potential carriers in controlled, modulated drug delivery, great interest has also been focused on biopolymer-based hydrogels. Due to their advantages like biocompatibility, biodegradability, and low cost, biopolymers have been widely used in the developmen...
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SYNTHESIS, CHARACTERISATION AND ANTIMICROBIAL EVALUATIONS OF SOME NOVEL 1, 3, 4-THIADIAZOLE DERIVATIVES
A series of 1, 3, 4-thiadiazole derivatives were synthesized. The structures of these compounds were established by means of IR, 1H-NMR and mass spectrum analysis. All the compounds were evaluated for antibacterial and antifungal activities. Most of the compounds have shown significant antibacterial and antifungal activity when compared with the standard drugs...
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RENAL FUNCTION OUTCOMES IN PATIENTS RECEIVING TDF – CONTAINING ANTIRETROVIRAL THERAPY: A RETROSPECTIVE PILOT STUDY IN NAMIBIA
Introduction and Aims: Combination antiretroviral therapy (cART) has improved morbidity and mortality in patients with HIV across countries including countries in sub-Sahara Africa. However, cART is associated with renal impairment. The lack of pre-cART data in a recently published study limited the discussion on renal-based treatment outcomes with cART, which could have important clinical implica...
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PHYTOCHEMICAL ANALYSIS AND IN-VITRO ANTICANCER ACTIVITY OF DURANTA ERECTA L. (VERBENACEAE)
The aim of the present work is the evaluation of anticancer activity of Duranta erecta L. stem extracts and also an investigation of the phytoconstituents from the different extracts of the plant. Chloroform, ethyl acetate, methanol and aqueous extracts of Duranta erecta L. stem were tested for their anticancer activity on three cancer cell lines, i.e., MCF-7 (Breast), HL-60 (Leukemia), and HT-29 ...
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ISOTRETINOIN ANTI-ACNE GEL FOR THE MANAGEMENT OF P. ACNE INFECTION
The object of the paper is the development of anti-acne gel of isotretinoin and evaluated for as potential formulation to treat Acne vulgaris. The isotretinoin based anti-acne gel was prepared by using carbopol 940 polymers and evaluated for solubility, drug interaction, drug release, pH, viscosity and spreadability. In-vitro drug release through Franz diffusion cells, acute skin irritation test a...
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ESTIMATION OF PROTEINS IN PLANTS OF FORENSIC SIGNIFICANCE (RICINUS COMMUNIS AND CANNABIS SATIVA) BY UV-SPECTROPHOTOMETRY AND GEL ELECTROPHORESIS METHOD
Proteins play a significant role in living beings. In animals, where proteins are involved in the body built, the formation of tissues, organs, etc., in plants, proteins regulate the respiration, photosynthesis, growth, and reproduction. There are some proteins which are specific to the plant or a particular species of plant. Proteomics is a multidisciplinary branch of science that deals with the ...
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ESTIMATION OF QUERCETIN CONTENT IN THREE DIFFERENT SPECIES OF EUPATORIUM BY HIGH-PERFORMANCE THIN-LAYER CHROMATOGRAPHY
Three different species of Eupatorium namely E. glandulosum, E. odoratum and E. triplinerve belongs to the family Asteraceae are selected for the analysis of quercetin content. Leaves are extracted with ethanol and water and used for the analysis of quercetin by HPTLC technique using the mobile phase containing toluene: ethyl acetate: formic acid: methanol (5.5:4:1:0.5). Determination of quercetin...
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