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ESTIMATION OF SOME HEAVY METALS BIOACCUMULATION IN TISSUES OF THE INTESTINAL CESTODA POSTGANGESIA ARMATA AND ITS DEFINITIVE HOST; THE EUROPEAN CATFISH SILURUS GLANIS (L.) FROM TIGRIS RIVER PASSING THROUGH NORTHERN N. GOVERNORATE, IRAQ
Objective: The purpose of the study is to pursue some heavy metals in the aqueous environment of Tigris river that passes through Mosul city prior to the bioaccumulation of such metals in catfish Silurus glanis and its intestinal tapeworm Postgangesia armata. Methods: Silurus glanis, a freshwater fish were hunted from Tigris river passing through Al-Rashidiya region/Nineveh Governorate, North Iraq...
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SYNTHESIS AND ANTIMICROBIAL EVALUATION OF 2-(4-FLUORO BENZYLTHIO)-N-(SUBSTITUTED PHENYL)PYRIMIDINE-4-AMINES
Reaction of 4-fluorobenzylchloride with 2-thiouracil (1) gave 2-(4-fluorobenzylthio)pyrimidin-4(3H)-one (2), which on chlorination with POCl3 furnished 4-chloro-2-(4-fluorobenzylthio)-4-chloropyrimidine (3). This intermediate when treated with various substituted anilines gave desired targeted compounds 4(a-k) in 50-90% yield. Structural assignments of the synthesized compounds were based on their...
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A COMPREHENSIVE REVIEW ON VIRAL ZOONOSIS: EMPHASIZING ON PATHOGENESIS, DIAGNOSIS, TREATMENT, PREVENTION STRATEGIES AND FUTURE PERSPECTIVES
Zoonoses are human diseases caused by animal pathogens or animal diseases that are transmissible to humans. They are caused by all types of pathogenic agents, including bacteria, parasites, fungi, viruses, and prions. Zoonotic diseases can be transmitted to humans by infected saliva, aerosols, contaminated urine or feces, and direct contact with the animal or pathogenic microbes. Furthermore, tran...
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CHARACTERISTICS, TREATMENT PATTERNS AND OUTCOMES OF PATIENTS WITH SMALL CELL LUNG CANCER – A RETROSPECTIVE ANALYSIS
PURPOSE: The aim of this retrospective study is to present data of patient characteristics, treatment patterns, and treatment results in an unselected patient population with small cell lung cancer (SCLC) in limited disease (LD) and extensive disease stage (ED). MATERIAL AND METHODS: All patients of carcinoma lung from April 2007 to December 2009 were analyzed for present study, conducted i...
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DEVELOPMENT AND OPTIMIZATION OF ORODISPERSIBLE TABLETS OF SEROTONIN HYDROCHLORIDE
The aim of the present work is to develop the formulation the orodispersible tablets of Serotonin hydrochloride. The tablets were prepared by direct compression technique using microcrystalline cellulose (MCC) as directly compressible diluents. Superdisintegrants such as Croscarmellulose sodium (CCS) Sodium starch glycolate (SSG) and Crospovidone were used. Method: Using different concentrations o...
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BINUCLEAR Fe(III), Co(II), Ni(II), Cu(II) AND ZN(II) COMPLEXES WITH SCHIFF BASE 4, 4-(1, 4-PHENYLENE BIS(AZAN-1-YL-1- YLIDENE)) BIS(METHAN-1-YL-1-1-YLIDENE)-1, 2-DIOL. SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION
Condensation reaction of 1, 4-phenylene diamine and Protochatechu aldehyde in 1:2 molar ratio resulted in the formation of new Schiff base ligand 4, 4-(1,4-phenylene bis(azan-1-yl-1-ylidene))bis(methan-1-yl-1-1-ylidene)-1, 2-diol; (H4L) .From the direct reaction of the ligand (1) with Co(II), Ni(II) and Cu(II) chlorides and Fe(III) and Zn(II)nitrates in 2M:1L molar ratio, the five new neutral comp...
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COMPREHENSIVE STUDY OF ACACIA LEUCOPHLOEA (ROXB.): TRADITIONAL USES, PHYTOCHEMISTRY AND PHARMACOLOGICAL SIGNIFICANCE
Herbal remedies have been utilized in medical practice for thousands of years and are recognized notably as a significant and widely available resource for health treatment. Traditional botanicals and herbal supplements have been deemed to be mild, non-toxic and even safe due to their natural nature. Acacia leucophloea (Roxb.) Willd. belongs to the family Mimosaceae, recognized as a diverse reso...
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EFFECT OF SINTERING CONDITION ON PHYSIO-CHEMICAL PARAMETERS AND DRUG RELEASE CHARACTERISTICS FROM POLYMERIC MATRIX TABLET OF ATENOLOL FOR CONTROLLED RELEASE
Sintering technique, a relatively new, convenient, economic process for making polymeric matrices for controlled release is described here. The objective of the present investigation was to prepare thermally sintered matrix tablets of Atenolol using Eudragit RS 100 as sintering polymer and to study the effect of thermal treatment on drug release; physiochemical properties of the prepared tablets. ...
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LETHAL EFFECTS OF PISTACIA ATLANTICA LEAVES EXTRACT AGAINST PROTO-SCOLECES OF HYDATID CYSTS
Surgery is one of the best options to treat cystic echinococcosis (CE, hydatid cyst). To date, surgeon used different protoscolicidal drugs to eliminate of protoscoleces during CE surgery, but most of these agents have some serious side effects. The current study aims to explore the in-vitro protoscolicidal effects of Pistacia atlantica leave extract against hydatid cyst proto-scolices. Proto-sc...
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TASKS OF COMPLIMENTARY AND FUNCTIONAL TRIO-MINERALS IN HYPERTENSION
Micronutrient deficiencies such as potassium, magnesium and calcium are very common in the general population and it is more predominantly present in the individuals with hypertension and cardiovascular patients. These deficiencies will have a massive impact on present and future cardiovascular health outcomes such as hypertension, myocardial infarction, stroke, etc. Recent efforts to reduce the p...
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