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CHEMICAL COMPOSITION OF FAGOPYRUM ESCEULENTUM MOENCH SEED THROUGH GC-MS
Medicinal herbs are a precious heritage for us and since long is a part of traditional as well modern system of medicine. These herbs provide less toxic and more effective drug molecules which are helpful in various ailments. In the present work, we have focused on an edible herb which bears a large number of medicinal properties. Fagopyrum esceulentum Moench (Buckwheat) has a long tradition of be...
1923
1065
ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) IN HAIL REGION, SAUDI ARABIA
Background: Acute respiratory distress syndrome (ARDS) is a medical condition occurring in critically ill patients characterized by extensive inflammation in the lungs and associated with several complications. Therefore, the present study aimed to identify the common risk factors associated with ARDS in Hail Region, Northern Saudi Arabia. Methodology: This study investigated retrospectively 68 pa...
1923
1029
USE OF ATENOLOL AND OLMESARTAN AS AN ADD-ON THERAPY WITH CALCIUM CHANNEL BLOCKER IN HEMODIALYSIS PATIENTS FOR HYPERTENSION
Background: Management of hypertension in hemodialysis patients was never the same in all and tends to involve a various classes of drugs with respect to their disease conditions, response to drug therapy, medication adherence, and many more. Atenolol and Olmesartan can be used as add-on therapy in managing hypertension with calcium channel blockers. Methodology: Blood pressure was monitored using...
1922
435
CYANOBACTERIA ASSISTED BIO-REDUCTION OF SILVER NANOPARTICLE CONJUGATES AND STUDY ON THEIR CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY AGAINST PATHOGENIC BACTERIA
Green nanotechnology has recently emerged as an area of research involving more eco-friendly and energy-efficient approaches for the synthesis of inorganic nanoparticles. The point of the present investigation is to evaluate the capacity of selected strains of freshwater Cyanobacteria (Microalgae) for their capability to biosynthesize silver nanoparticles by utilizing both live biomass of microalg...
1921
792
A REVIEW ON CUBOSOME: A NOVEL APPROACH FOR DRUG DELIVERY
Cubosomes are very stable nanoparticles, which consist of cavernous or honeycombed structures. Cubosomes are formed from some amphiphilic lipids and stabilized by a polymer. They are known as bicontinuous cubic phase liquid crystals. The bicontinuous word refers to the two continuous but non-intersecting aqueous regions by a lipid bilayer. Cubosomes are self-assembled liquid crystalline particles ...
1920
1065
IN-VITRO COMPARATIVE ANTICANCER ACTIVITY STUDY OF METHANOLIC EXTRACT OF TRADITIONALLY USED MEDICINAL PLANT OF MIZORAM
Objective: The present study explores the anticancer potentially of plant sample based on the evidence from the ethnomedicinal practice of the plant. The main objective was to find out the in-vitro comparative anticancer activity of the various methanolic extract. Method: Plants samples such as Mikania micrantha, Allium hookeri, Eryngium foetidium, and Alpinea galanga were collected, identified, a...
1919
841
GASTROPROTECTIVE EFFECT OF ETHANOLIC EXTRACT OF TRICHOSANTHES DIOICA FRUIT ON EXPERIMENTAL GASTRIC ULCER IN RATS
Peptic ulcer is a condition associated with a number of factors involving excessive acid secretion in the stomach. This condition is difficult to control with single drug therapy and complete cure cannot be achieved. Even after discontinuation of the drug the relapse rate is high, and the long-term use of synthetic drugs produces adverse effects on the human body. The present study is expected to ...
1918
877
IMPROPER TECHNIQUE OF USING METER DOSE INHALER IN A SAMPLE OF ASTHMATIC PATIENTS
Background: Improper asthma inhaler device use was most likely one of the major causes associated with uncontrolled asthma and frequent respiratory clinic visits. Therefore, assessment of the effect of the improper use of metered dose inhaler device in the control of bronchial asthma, and the factors that have important impact on asthma management and control. Objectives: To evaluate the inhaler t...
1918
789
PHYSICOCHEMICAL CHARACTERIZATION OF 99mTECHNITIUM – LUTEOLIN AS RADIOPHARMACEUTICAL PREPARATION FOR ANTIOXIDANT COMPOUND
The objective of this study was to formulate luteolin with radioisotope Technetium-99m (99mTc) to be 99mTc-Luteolin as an antioxidant compound. After optimization, this radiopharmaceutical preparation should be examined for its physicochemical characteristics, such as radiochemical purity, stability, lipophilicity, protein plasma binding, electronic charge, and stability test. The formulation was ...
1918
625
DESIGN AND OPTIMIZATION OF CAPECITABINE NIOSOMES DERIVED FROM PRONIOSOMES
The aim of this investigation was to design and optimize the Capecitabine niosomes derived from proniosomes using central composite design. Two independent variables viz., the molar ratio of drug to cholesterol (X1), surfactant loading (X2) and two dependent variables viz., the percentage drug entrapment (PDE) and mean volume diameter (MVD) were selected for the study. Proniosomes were prepared by...
1916
809