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STABILITY INDICATING ASSAY OF TELMISARTAN IN TABLETS
An accurate, simple, precise, rapid stability-indicating assay method was developed and subsequently validated for the estimation of Telmisartan in API and Tablets. The best separation of the drug was achieved on Kromasil C18 (4.6 × 150 mm, 5 µm) with the mobile phase consisted of mixture of 0.01 M Phosphate buffer (pH: 3) and Acetonitrile in ratio of (40:60%) at flow rate of 2 ml/min, with dete...
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FORMULATION AND EVALUATION OF DRY POWDER SUSPENSION USING HERBAL SEED EXTRACT
Introduction: Herbs, which have been used to cure numerous ailments since ancient times, are important in building the foundation of modern medications. They are relatively safe to use, easily available, and also affordable. The present study aimed to investigate dry powder suspension formulated with Linum usitatissimum seeds extract, Cucurbita pepo seeds extract, Sesamum indicum seeds extract and...
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GASTROPROTECTIVE EFFECT OF ETHANOLIC EXTRACT OF TRICHOSANTHES DIOICA FRUIT ON EXPERIMENTAL GASTRIC ULCER IN RATS
Peptic ulcer is a condition associated with a number of factors involving excessive acid secretion in the stomach. This condition is difficult to control with single drug therapy and complete cure cannot be achieved. Even after discontinuation of the drug the relapse rate is high, and the long-term use of synthetic drugs produces adverse effects on the human body. The present study is expected to ...
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VARIOUS MEDICINAL PLANTS: A PROMISING TREATMENT FOR MULTIDRUG-RESISTANT BACTERIA ISOLATED FROM WOUND INFECTION
Bacteria have proved remarkably developing resistant to a known antibiotic; however, Medicinal plants have manifested notably useful for the control of bacterial infections. This study aimed to isolate and identify the multidrug-resistant bacteria from wound infection, then examine the antibacterial activity of different concentration of the ethanolic extracts of Cymbopogon proximus, Azadirachta i...
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ENHANCED MECHANISM OF METAL NANOPARTICLES USING SYZYGIUM CUMINI AS A POTENTIAL SYNTHESIZER AND ITS INHIBITORY EFFECT
In recent years metallic nanoparticles, represent one of the most comprehensively studied materials because of their application in biology The synthesis of silver nanoparticles using biological entities has received immense attention in the area of research. Medicinal plants have attracted interest over antibiotics due to a rapid increase in the rate of infections, development of antibiotic resis...
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ANTI-MITOTIC ACTIVITY OF GANODERMA APPLANATUM
Traditionally, mushrooms have importance in the diet. Since they possess both nutritional and medicinal value, research on mushrooms is the new area for developing lead molecules to treat cancer and other ailments. Ganoderma is a famous genus in the medicinally important mushrooms. Cancer is a fatal disease in which uncontrolled proliferation is the major crunch point to be considered. The current...
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ANTIOXIDANT, ANALGESIC AND ANTIMICROBIAL ACTIVITIES OF DIFFERENT FRACTIONS FROM METHANOLIC EXTRACT OF PSIDIUM GUAJAVA L. LEAVES
Psidium guajava Linn. the most popular and widely cultivated fruiting plant all over Bangladesh. The present study was aimed to investigate the antioxidant, analgesic and antimicrobial activities of n-hexane (HPG), chloroform (CLPG) and ethyl acetate fractions (ET APG) obtained from methanol extract of Psidium guajava (MPG) leaves. The in-vitro antioxidant activity of fractions HPG, CLPG and ET AP...
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DEVELOPMENT, CHARACTERIZATION AND EVALUATION OF NANOCRYSTALS OF NITROFURANTOIN
Nitrofurantoin is a broad-spectrum bactericidal antibiotic that affects both gram-negative and gram-positive bacteria. Nitrofurantoin exhibits bacteriostatic or bactericidal effects by inhibiting the synthesis of DNA, RNA, protein, and cell wall synthesis. Nanocrystals of NFT were prepared by a cold high-pressure homogenization technique. To improve the dissolution rate, the drug was formulated in...
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DEVELOPMENT OF RP-HPLC METHOD FOR THE ESTIMATION OF ACOTIAMIDE HYDROCHLORIDE HYDRATE USING AQbD APPROACH
The current studies details QbD enable the development of a simple, rapid, and cost-effective reverse phase high performance liquid chromatographic method for estimation of Acotiamide hydrochloride hydrate. The simple analytical RP-HPLC method was developed using Box-Behnken Design (BBD). In the present work, three independent factors were used, such as org phase (A), aqueous phase (B), and flow ...
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FORMULATION AND EVALUATION OF LANSOPRAZOLE AND DOMPERIDONE MOUTH DISSOLVING TABLETS
Lansoprazole and Domperidone, used as Proton pump inhibitor and antiemetic agents, especially for disease related to gastric ulcer. The purpose of the research was to improve aqueous solubility of drugs by β-CD using a different method, and perform phase solubility study of both drugs using β-CD and calculate Ks, and ∆Gt. Prepare Complex of LAN and DOM with β-CD using different methods like p...
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