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NICKEL OXIDE NANOPARTICLES SYNTHESIS BY CHEMICAL REDUCTION TECHNIQUE AND IT’S APPLICATION AS ANTIMICROBIAL AND DYE DEGRADING AGENT
Nanoparticles are fascinating materials that find many applications in basic and applied research. The chemical reduction technique is one of the easiest methods for synthesizing Nickel Oxide Nanoparticles (NiO NPs) in low-temperature ranges. Nickel Nitrate Hexahydrate (Ni(NO3)2.6H2O), Ascorbic acid, NaOH, and NaBH4 were applied as starting reagents to synthesize NiO NPs. Noble metal oxide nanopar...
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ROLE OF ROBOTICS IN HEALTH CARE SYSTEM DURING COVID-19 PANDEMIC
The essential part of robots in the medical services framework is principal to limit an individual to individual contact, defilement, and to guarantee cleaning, disinfection. Robots can be defined as an artificially intelligent physical system that is capable of interrelating with the environment. The term robot was coined from the Czech what "robota" which implies serf/worker. Robots are classifi...
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METHYLATION EFFECT OF APIGENIN 8-C-GLUCOSIDE TOWARDS ANTIOXIDANT POTENTIAL – A DFT STUDY
The extensive study on O - methylated flavonoids reveals that substitution with methyl group enhances the radical scavenging behavior in certain compounds. Due to potential applications of C-glycosides in metabolic engineering, methylation in these flavonoids needs to be analyzed in both theoretical and experimental levels for their radical scavenging behavior. In this work naturally occurring C- ...
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IN-SILICO TOOLS IN THE PREDICTION OF COUMARIN SCHIFF BASES AS POTENTIALLY ACTIVE COMPOUNDS: A COMPARATIVE STUDY
In the present study two subclasses of coumarin derivatives were selected 14 coumarin sulphonamides and 14 coumarin schiff bases i.e., totally 28 compounds from our earlier research work. A comparative study for two subclasses of coumarins by using various CADD (online and offline) softwares. Computational calculations and predictions of important molecular properties suggest that among the two su...
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2D QSAR STUDY OF INDOLE DERIVATIVES AS SELECTIVE COX-2 INHIBITORS
The NSAIDs are popular in reducing acute and chronic inflammation as they have no abuse liability. QSAR (Quantitative structure-activity relationship) approach is a very useful and widespread technique for drug design. 2D QSAR models are based on descriptors derived from a two-dimensional graph representation of a molecule. The 2D QSAR study was performed on selected twenty-four compounds from syn...
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EVALUATION OF ANTIDEPRESSANT ACTIVITY OF LITSEA FLORIBUNDA (BL.) GAMBLE – LAURACEAE USING ANIMAL MODELS
The genus Litsea, is used in traditional and indigenous Indian and Chinese medicines for the treatment of diarrhoea, stomach ache, dyspepsia, gastroenteritis, diabetes, edema, arthritis etc. The objective of the present study was to evaluate the antidepressant activity of leaf and stem bark aqueous and ethanol extracts of L. floribunda (LF) as well as its interaction with conventional antidepressa...
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A REVIEW ON OBESITY COMPLICATIONS AND ITS MANAGEMENT
The article focuses on the prevalence of obesity in India, increasing levels of childhood obesity, and the potential health hazards that result from obesity, thereby suggesting the necessary preventive measures and the prevailing natural and synthetic therapy that can help to cure the disease, thus spreading awareness about its severity and necessity for treatment. Obesity in India has reached epi...
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COMBING THROUGH TRADITIONAL TEXTS TO PREVENT COVID-19 – A SCIENTIFIC APPROACH
The coronavirus pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is unique and unprecedented in many respects and has challenged healthcare systems worldwide. Currently, there is no specific treatment or cure in the Western medicine system. Research is underway to develop effective vaccines and medications for the disease. In this scenario, the scientific commun...
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FORMULATION AND EVALUATION OF METOPROLOL LOADED SOLID LIPID NANOPARTICLES
The main aim of the present study is to formulate and evaluate solid lipid nanoparticles of Metoprolol. Metoprolol is an anti-hypertension drug used in the treatment of hypertension, angina pectoris, and heart failure. Metoprolol belongs to BCS class-I, which has high solubility and high permeability. The drug needs to be administered frequently (2-3 times a day), and it has side effects and poor ...
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ASSESSMENT OF REPRODUCTIVE TOXICITY OF CONCOCTION OF ANDROGRAPHIS PANICULATA IN MALE WISTAR ALBINO RATS
Objective: To assess the reproductive toxicity of concoction of Andrographis paniculata in male Wistar albino rats. Methods: 18 male Wistar albino rats were divided into 3 groups with 6 animals in each group. Group 1 served as control and received distilled water. Group 2 and 3 received 0.5 ml of a concoction of Andrographis paniculata and Nilavembu kudineer (a concoction of 9 herbs) respectively ...
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