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A REVIEW ON TRADITIONAL MEDICINAL PLANTS USED AS ANTIDOTES IN THE TREATMENT OF SNAKE BITES IN INDIA
Envenoming and deaths resulting from snakebites are particularly important public health problems in the rural tropics. Snake envenomation is included since 2009 in the World Health Organization (WHO) list of Neglected Tropical Diseases, as this condition remains largely neglected by national and international health authorities. The only available specific treatment is antivenom therapy, which co...
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SIMULTANEOUS ESTIMATION OF CIPROFLOXACIN AND METRONIDAZOLE IN BULK AND TABLET FORMULATION BY UV SPECTROPHOTOMETRY
Three simple and economical UV-spectrophotometric methods have been developed and validated for simultaneous estimation of ciprofloxacin (CIP) and metronidazole (MET) in a tablet dosage form using distilled water as a green solvent. The proposed methods were; simultaneous equation method (method A), Q-absorbance ratio method (method B), and area under curve method (method C). λmax of CIP & ME...
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IN-VITRO COMPARATIVE ANTICANCER ACTIVITY STUDY OF METHANOLIC EXTRACT OF TRADITIONALLY USED MEDICINAL PLANT OF MIZORAM
Objective: The present study explores the anticancer potentially of plant sample based on the evidence from the ethnomedicinal practice of the plant. The main objective was to find out the in-vitro comparative anticancer activity of the various methanolic extract. Method: Plants samples such as Mikania micrantha, Allium hookeri, Eryngium foetidium, and Alpinea galanga were collected, identified, a...
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BIOMOLECULAR PROTECTIVE EFFECT OF THE METHANOLIC EXTRACT OF THE FLOWERS OF CAESALPINIA PULCHERRIMA, SWARTZ. AGAINST OXIDATIVE DAMAGE
Free radicals and reactive oxygen species (ROS) production above basal levels cause irreversible damage to the cell membrane, DNA and other cellular structures by oxidizing lipids, proteins and nucleic acids resulting in dysfunction of biomolecules within cells and, finally, cell death. These free radical-induced reactions are ascertained to play multiple roles in degenerative or pathological even...
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QUANTITATIVE ESTIMATION OF TOTAL PHENOLIC CONTENT OF TWO SPECIES OF PORTULACA OBTAINED BY USING MICROWAVE ASSISTED EXTRACTION AND ITS VALIDATION
Portulaca oleracea and Portulaca quadrifida have been used traditionally have been used for their pharmacological properties and consumed as a part of the diet. Anti-oxidative property of phytochemicals might play a role in their observed benefits, and phenolic compounds are known to be the major contributors towards the anti-oxidant property of phytochemicals. The objective of this study was to q...
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THE IMPACT OF CARCINOGENIC CHEMICAL USE AMONG CARDAMOM FARMERS AND THE PREVALENCE OF CANCER IN IDUKKI DISTRICT, KERALA
The prevalence of cancer is drastically increasing among cardamom farmers using chemical pesticides in Idukki district. The chemicals, mainly Organochlorine and organophosphates, result in various disease conditions. The main aim of the study was to explore the prevalence of cancer and other disease conditions among farmers and other people who were exposed to chemical pesticides. A community-base...
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NON ENZYMATIC AND ENZYMATIC ANTIOXIDANT STATUS OF WISTAR RAT ERYTHROCYTE AFTER DIETARY ZINC DEFICIENCY
Zinc deficiency is prevalent worldwide. The present study deals with the effect of dietary zinc deficiency on erythrocytes of Wistar rats. Male Wistar rats (40-50 g) were divided into 3 groups: control (ZC) fed 100 μg/g zinc; pair fed (PF) fed 100 μg/g zinc but the diet given was based on the diet consumed the previous day and zinc deficient (ZD) fed 1 μg/g zinc. The experiment was carried out ...
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ANALYSIS OF CUTANEOUS ADVERSE DRUG REACTIONS PRESENTING TO THE DERMATOLOGY DEPARTMENT OF A TERTIARY CARE TEACHING HOSPITAL: A PROSPECTIVE, OBSERVATIONAL STUDY
Background: Cutaneous adverse drug reactions (CADRs), having a wide range in terms of its spectrum, are an important cause of morbidity and mortality. They comprise 2-3% of all ADRs. This study was conducted to analyze various parameters of CADRs at our setup. Methodology: This prospective, observational study was carried out for 1 year at our setup after ethical approval. Those diagnosed as CADRs...
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IMPACT OF HYDROTHERMAL ISOLATION METHOD ON THE RECOVERY OF FENUGREEK SEED HEMI-CELLULOSE ANALYZED THROUGH FTIR-DSC-SEM INTERPRETATIONS
Natural Herbal components like seeds mucilages, exudates, gums, polysaccharides, celluloses, hemicelluloses, starch, etc. are now a day’s exploited as excipients. Literature reveals medicinal, nutraceutical and pharmaceutical uses of fenugreek seed hemicelluloses in dosage form design. Hemicelluloses like galactomannans are water-soluble polysaccharides highly susceptible to hydrolysis either by...
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BIOFILM AND METTALO BETA-LACTAMASE PRODUCTION IN ASSOCIATION WITH SERUM RESISTANT ACTIVITY AMONG CLINICAL STRAINS OF PSEUDOMONAS AERUGINOSA
Biofilms are communities of bacteria that are append to a surface and play significant role in the persistence diligence of bacterial infections. Bacteria with a biofilm are more defiant to antibiotics compared with planktonic bacteria. Biofilm producing bacteria are able to take possession on medical devices such as catheters and implants. The incidence of Biofilm producing microorganism runs aro...
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