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PHYTOCHEMICAL SCREENING, ANTIOXIDANT AND CARBOHYDRATE DIGESTING ENZYME INHIBITORY POTENTIAL OF LEUCAENA LEUCOCEPHALA LEAVES EXTRACT
The study aims to investigate the antioxidant and antidiabetic activity of Leucaena leucocephala ethanol leaf extract (LLME). L. leucocephala leaves extraction was carried out by the maceration method. Phytochemical analysis was performed using standard analytical procedures. Diphenyl picrylhydrazyl (DPPH) radical and 2, 2’-azinobis (3-ethylbenzathiazoline-6-sulfonic acid) (ABTS) radical scaveng...
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EFFECT OF PENTOXIFYLLINE ON SERUM CRP LEVELS IN HEMODIALYSIS PATIENTS COMPARED WITH PLACEBO
Introduction: Inflammation indicates with increased levels of inflammatory markers such as CRP is common in hemodialysis patients. Higher levels of CRP is strong predictor of morbidity and mortality in dialysis patients. The aim of this study was to evaluate the effect of pentoxifylline on serum CRP levels in hemodialysis patients compared with placebo. Methods: In this randomized clinical trial, ...
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FERTILITY EFFECT OF CYCAS CIRCINALIS AND IONIDIUM SUFFRUTICOSUM IN SENILITY INDUCED STERILITY OF MALE WISTAR RATS – A HISTOMORPHOMETRIC STUDY
Ageing is associated with the diminished function of various tissues in the body. The gonadal function declines with age. In male, there is progressive atrophy of the sperm producing elements of the testes, resulting in diminished spermatogenesis. Many natural nontoxic herbs were found to enhance the fertility in male. The study is done to evaluate the effect of Cycas circinalis (Cc) and Ionidium ...
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SYNTHESIS OF SOME- 6- SUBSTITUTED- 6H- PYRROLO [3, 4-D] PYRIDAZINE DERIVATIVES AND THEIR EVALUATION FOR IN-VIVO ANTI-CONVULSANT ACTIVITY IN ALBINO RATS
Present studies on the synthesis and evaluation of anticonvulsant activity of some 6- Substituted- 6H- Pyrrolo [3, 4-d] Pyridazine derivatives. In the preliminary screening for anticonvulsant activity in albino rats, all the synthesized compounds were found to be active, even more than standard at dose 50mg/kg body weight....
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BIOCHEMICAL STUDY OF AN ENDANGERED ETHNOMEDICINAL PLANT CURCULIGO ORCHIOIDES GAERTN. OCCURRING IN PURULIA DISTRICT OF WEST BENGAL, INDIA
Ethnic peoples from Purulia district of West Bengal in India use a lot of plants for their primary health care without studying phytochemical analysis and biological activities in detail. Main objectives of the present study are to evaluate the antibacterial and antioxidant activities of the whole plant extract of Curculigo orchioides using polar and nonpolar solvents. Total phenol content (TPC) w...
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COMPARATIVE EVALUATION OF DICLOFENAC AND MELOXICAM AS TABLETS AND AS TRANSMUCOSAL MUCOADHESIVE PATCHES IN DENTAL PAIN REDUCTION
Aims and Objectives: To evaluate and compare diclofenac and meloxicam as tablets and as mucoadhesive patches in the control of odontogenic pain. Materials and Methods: 60 patients of either sex with acute dental pain were included in the study. Informed consent was obtained from each patient and they were randomly divided into 4 groups. Group A1 received meloxicam tablets, A2 meloxicam mucoadhesiv...
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MIR AND NIR SPECTROSCOPY AS RAPID METHOD TO QUANTIFY MOLSIDOMIN IN GENERIC TABLET
This work investigates the potential of Partial Least Square (PLS) regression using two vibrational spectroscopies as mid infrared (MIR) and near infrared (NIR) spectroscopies for the quantification of molsidomin in tablets. Two very simple, rapid, inexpensive and green strategies were applied for this determination. Powder blends containing molsidomin and excipients were prepared. The excipients ...
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FORMULATION AND DEVELOPMENT OF QUERCETIN AND MONOAMMONIUM GLYCYRRHIZINATE LOADED GEL FOR THE TREATMENT OF MOUTH ULCER DISEASE
Diagnosis of oral ulcerative lesions might be quite challenging. Oral ulcerative lesions were categorized into three major groups as acute, chronic, and recurrent ulcers. Helicobacter pylori (H. pylori) have been found in the oral cavity and stomach, and its infection is one of the most frequent worldwide. There is a close relation between H. pylori infection in the oral cavity and the stomach. H....
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BIOSYNTHESIS OF SILVER NANOPARTICLES USING EXTRACTS OF TWO SPECIES OF PORTULACA AND THEIR ANTIBACTERIAL ACTIVITY
Portulaca oleraceae commonly known as Purslane and Portulaca quadrifida commonly known as chicken weed are consumed in salads, pickles, and soup in Asia, Africa, and Mediterranean region. In the traditional systems of medicine in Asia and Africa, they have been attributed to several pharmacological properties. Phytochemical investigations point to the presence of various beneficial constituents in...
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AN ANALYTICAL STUDY ON THE CLINICAL EFFICACY OF PEENISA PUGAI TOWARDS THE MANAGEMENT OF PEENISAM (SINUSITIS)
Pugai (fumigation) is one among the external medicines in treating a variety of diseases with the fumes of herbs or aromatic substance. Peenisa pugai is an external therapeutic measure that has been indicated in Siddha literature for the effective management of Peenisam that can be symptomatically correlated with that of Sinusitis. The aim of the present Pilot study was to compare the efficacy of ...
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