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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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44.

ASSESSMENT OF QUALITY OF LIFE IN DIALYSIS AND NON-DIALYSIS CHRONIC KIDNEY DISEASE PATIENTS

Quality of life is an essential measure that proves the effectiveness of health care, health level, and well-being. Kidney diseases are one of the major health problems that affect Quality of life. This study aimed to assess the quality of life in dialysis (CRF-D) and non-dialysis (CRF-ND) chronic renal failure (CRF) patients using Kidney Disease Quality of Life-short form (KDQOL-SFTM) and identif...

N. Venkateswaramurthy *, M. S. Islam, R. C. Habeeba and R. Sambathkumar

Department of Pharmacy Practice, J. K. K. Nattraja College of Pharmacy, Kumarapalayam, Tamil Nadu, India.

DOI: 10.13040/IJPSR.0975-8232.10(6).2970-74

2970-2974

3557

1488

34.

ROLE OF LIQUID MEMBRANE HYPOTHESIS IN THE MECHANISM OF ACTION OF ERTAPENEM

The role of liquid membrane hypothesis has been studied in the mechanism of action of Ertapenem. In the present study transport of selected permeants (glucose, p-amino benzoic acid and ions like magnesium, ammonium, phosphate, calcium, sodium, potassium and chloride) through liquid membrane generated by Ertapenem in series with supporting membrane has been studied. The results indicate that the li...

Abhay K. Jain *, Manish Srivastava and Sharad K. Gupta

Department of Chemistry, D. D. U. Gorakhpur University, Gorakhpur - 273009, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(7).2890-95

2890-2895

3555

1563

40.

BIOCHEMICAL CHARACTERIZATION OF PROTEASE FROM ZINGIBER OFFICINALE RHIZOME BY USING NEURAL NETWORKING APPROACH

Biochemical characterization of enzyme is the most fundamental aspects of enzymology from industrial point, as it is desirable to choose an enzyme which will have the fastest reaction rate per unit amount of enzyme which indicates the maximum effect for the minimum amount of added catalyst. In this study, Protease enzyme was extracted from Z. officinale and purified by using various down streaming...

N. Jabalia*, Kanagarethinam, P. C. Mishra and N. Chaudhary

Amity Institute of Biotechnology, Amity University, Noida, Uttar Pradesh, India.

DOI: 10.13040/IJPSR.0975-8232.8(12).5276-81

5276-5281

3555

1539

17.

TRACE LEVEL QUANTIFICATION OF CYPIONYL CHLORIDE IN TESTOSTERONE CYPIONATE BY PRE COLUMN DERIVATIZATION WITH 2-BUTANOL BY GAS CHROMATOGRAPHY WITH ELECTRON IMPACT IONIZATION DETECTOR

The author has been proposed the precolumn derivatization method for the trace level quantification of cypionyl chloride in testosterone cypionate, it maybe potential impurity in the testosterone cypionate, it has to quantify in the testosterone drug Substance. The method development of cypionyl chloride has been started with gas chromatography with FID detector. The detection of cypionyl chloride...

N. Rajana *, P. Madhavan, J. M. Babu, K. Basavaiah and D. R. Devi

Scientist in Analytical Research and Development, Custom Pharmaceutical Services, Dr. Reddy’s Laboratories Ltd., Miyapur, Hyderabad, Telangana, India.

DOI: 10.13040/IJPSR.0975-8232.9(7).2767-72

2767-2772

3555

1931

16.

ACETYLCHOLINESTERASE INHIBITORY ACTIVITY OF DOREMA AMMONIACUM GUM EXTRACTS AND MOLECULAR DOCKING STUDIES

Ammoniacum gum is traditionally used as an expectorant, stimulant, antispasmodic, catarrh, asthma, chronic bronchitis, and enlargement of liver and spleen in Medicine. The Soxhlet extraction of the oleo gum resin of D. ammoniacum was carried out with organic solvents including hexane, dichloromethane, chloroform, ethyl acetate, and methanol. The screening of the anti-alzheimer activity of the extr...

M. Mazaheritehrani *, R. Hosseinzadeh, M. Mohadjerani, M. Tajbakhsh and S. N. Ebrahimi

Department of Organic Chemistry, Faculty of Chemistry, University of Mazandaran, Babolsar, Iran.

DOI: 10.13040/IJPSR.0975-8232.11(2).637-44

637-644

3555

1664

37.

VIRTUAL TOXICITY STUDIES OF NOVEL SPIROAZETIDIN-2-ONES TETHERED WITH FURANS

Background and aim: Spiroazetidin-2-ones and furans are commonly used as anti-bacterial, anti-fungal, anti-inflammatory, cardiovascular activities, anticancer, antiparkinson agents etc. The purpose of this study was to perform virtual toxicity studies of the synthesized compounds 1-(substitutedphenyl)-3-chloro-5,9-bis(furan-2-ylmethylidene)-1-azaspiro[3.5]nonan-2-ones (3a-3h). Materials and method...

R. Srikala* and M.N. Babu

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, M.S. Ramaiah University of Applied Sciences, Bangalore, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.9(1).286-91

286-291

3554

1569

66.

DEVELOPMENT OF MALTODEXTRIN BASED PRONIOSOMES DERIVED NIOSOMES OF OFLOXACIN

Nanotechnology is an advancing technology expected to bring revolutionary changes in the field of life sciences including drug delivery. The advance in nanotechnology helps in the preparation of new pharmaceutical formulations with high benefits. One of its approaches is to stabilize the niosomal drug delivery system without affecting its properties have resulted in the development of proniosomes,...

G. S. Ravi *, A. Dubey and S. Hebbar

Department of Pharmaceutics, N. G. S. M. Institute of Pharmaceutical Sciences, NITTE (Deemed to be University), Paneer, Deralakatte, Mangaluru, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.10(3).1485-90

1485-1490

3554

1486

31.

BINDING TO AND RETENTION BY MUCOSAL CELLS OF THE TAMARINDUS INDICA SEED POLYSACCHARIDE: VISUAL EVALUATION BY MEANS OF INORGANIC AND ORGANIC MARKERS

The aim of this study was to investigate the possibility of using inorganic and organic markers to visualize the ability of the transparent polysaccharide (TSP) polymer isolated from the endosperm of the seed kernel of Tamarindus indica, a tree that mainly grows in India and South-East Asia, to bind to human mucosal cells. A layer of human buccal cells was prepared on slides and overlaid by 0.2 ml...

P.C. Braga*, M. Dal Sasso, M. Culici

Department of Pharmacology, School of Medicine, University of Milan, Milan, Italy

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(6).1735-40

1735-1740

3553

1370

55.

PRELIMINARY PHYTOCHEMICAL INVESTIGATIONS AND ANTIEPILEPTIC ACTIVITY OF TREMA ORIENTALIS (LINN.) EXTRACTS

Objective: The antiepileptic potential of the petroleum ether (PETO) and methanolic extracts (METO) of the whole plant (roots, leaves, stem, and bark) of Trema orientalis (family: Ulmaceae) was evaluated using different experimental models of epilepsy in rats and mice. Materials and Methods: The anti-epileptic activity of the PETO and METO was evaluated using Picrotoxin, Isoniazid, and NMDA induce...

K. M. Geetha *, K. Vishnnupriya, F. Jaferi and V. Murugan

Department of Pharmacology, College of Pharmaceutical Sciences, Dayananda Sagar University, Bangalore, Karnataka, India.

DOI: 10.13040/IJPSR.0975-8232.10(8).3957-62

3957-3962

3553

1595

52.

ROLE OF SERUM BILIRUBIN IN CLINICALLY ADMITTED PATIENTS TO PREVENT THE RISK OF CARDIAC DISEASES

ABSTRACT: Background: Coronary artery disease /coronary vascular disease (CAD/CVD) remains the first killer and common silent disease in the world. The lipid profile plays the essential role in CAD development with lipid oxidation.  Lipid oxidation, which accepted as an important element of arterial plaque formation and atherosclerosis, is involved in the patho physiology of   CVD. Bilirubin...

Neha Sharma*, Sadhna Sood and Girdhar Gopal Kaushik

Department of Biochemistry, SRMS-Institute of Medical Sciences, Bareilly, Uttar Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.5(3).1077-82

1077-1082

3551

1788