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A REVIEW ON THE PHARMACOGNOSTICAL, ECOLOGY AND PHARMACOLOGICAL STUDIES ON MARINE RED ALGAE – HYPNEA VALENTIAE
Seaweeds are the potential marine living resources in the world. More than 20,000 seaweeds are distributed throughout the world, of which only 221 (1.1%) are commercially utilized, which includes 145 species for food and 110 species for phycocolloid production. The biodiversity of the marine environment and the associated chemical diversity constitute a practically unlimited resource of new active...
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HIGH – PERFORMANCE LIQUID CHROMATOGRAPHY METHOD VALIDATION AND DEVELOPMENT STRATEGY FOR RIFABUTIN
A simple, economical, accurate and precise high performance liquid chromatographic method was developed and validated for the determination of rifabutin. A Shimadzu LC-2010C HT version 3.01 system using a C-18 column with dimensions of 250 × 4.6 mm and silica particle size of 5 μm. Isocratic elution was employed with methanol, acetonitrile and water (75:25 v/v) were used. The flow rate was 1 ml/...
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EVALUATION OF SAFETY PROFILE OF ANTI HYPERTENSIVE DRUGS WITH THE EFFECT OF PATIENT COUNSELING
Objective: To establish does response relationship to the hypertensive patients and ensure safety profile of drugs through counseling of patients. Method: Patients who have suffered by secondary hypertension with blood pressure range of above 145-170/100-110 mmHg are selected and divided in two groups. First group of patients to administer for Nifedipine 5mg and furosemide 40mg administered for...
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PREVENTION OF RADIATION INDUCED HEMATOLOGICAL ALTERATIONS IN MICE BY ALSTONIA SCHOLARIS EXTRACT
Backround: The present study has been carried out to evaluate the radio-protective effects of Alstonia scholaris extract (ASE) on peripheral blood of mice. Materials & Methods: Male Swiss albino mice were selected from an inbred colony and assorted into 4 groups. Animals in Group I were administered with double distilled water (DDW), volume equal to ASE, by oral gavage to serve as vehicle t...
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THERAPEUTIC EFFECT OF TAMARINDUS INDICA EXTRACTS ON THE PATHOGENESIS OF ENTAMOEBA HISTOLYTICA IN-VIVO
Entamoeba histolytic is a protozoan parasite which causes amoebiasis, about 50 million people are affected yearly, and it caused more than 100,000 deaths per year. The study investigates the therapeutic effect of ethanolic and aqueous Tamarindus indica leaves extracts on infected rats with Entamoeba histolytica. Twenty-one Rattus norvegicus rats were infected with Entamoeba histolytica and divided...
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SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW4-(SUBSTITUTED\ARYL)-((1, 3–DIPHENYL-1H-PYRAZOLE-4-YL) METHYLENEAMINO)-1, 5-DIMETHYL-2-PHENYLPYRAZOLILDIN-3-ONE DERIVATIVES
Schiff Base derivatives are important class of compounds. They possess different types of Biological activities like antibacterial, antiviral, anti HIV, antifungal etc. Schiff base derivatives are prepared by the condensation of aldehyde and amine and these compounds are characterized by chemical and instrumental methods. Their important biological properties have been investigated....
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SYNTHESIS AND SPECTRAL STUDY OF 2-(4-{[(SUBSTITUTEDPHENYL)IMINO]METHYL}PHENOXY)ACETO HYDRAZIDE
Heterocyclic Compounds having a valuable place in a Heterocyclic Chemistry and Heterocyclic Compounds having an excellent properties such as drugs, dyes etc, These compounds shows anti-microbial, anti-fungal, anti-bacterial, anti-inflammatory, anti-diabetic, anti-hypertensive etc. properties. In present investigation, we have prepared 2-4-{[(substitutedphenyl)imino]methyl} phenoxy)acetohydrazide f...
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DEVELOPMENT AND VALIDATION OF HPTLC METHOD FOR ESTIMATION OF FLUOXETINE IN ITS CAPSULE FORMULATION
An HPTLC method for estimation of Fluoxetine in its capsule formulation has been developed. It employs aluminium backed silica gel 60 F254 TLC plates, (20 cm × 10 cm, layer thickness 0.2 mm) prewashed with methanol and mobile phase comprising of toluene: 2-propanol: ammonia 2:2:0.4 (v/v/v). The developing solvent was run upto 80 mm in Camag chamber previously saturated with 10.0 mL of solvent mix...
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ACTIVE COMPOUND FROM n-HEXANE FRACTION OF RAMPAI (LYCOPERSICON ESCULENTUM) LEAVES ETHANOL EXTRACT
Lycopersicon esculentum leaves had traditionally been used to stimulate hair growth in Lampung Pesisir tribes, Tanggamus Regency, Lampung, Indonesia. This study aimed to examine the active compounds from the n-hexane L. esculentum leaves. The study based on our previous research showing that the n-hexane had hair growth stimulating effects. The study started with sample collection, extracted by ma...
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HISTOPATHOLOGICAL ALTERATIONS IN KIDNEY DUE TO THE EFFECT OF VARIOUS STAGES OF NAGABHASMA (LEAD) PREPARATION
Background: Nagabhasma is a lead-based Ayurvedic medicine. Numerous reports indicate the toxic effects of lead used in this preparations on various systems of our body. But Ayurveda claims that the toxic effect of lead gets nullified thereby acquiring the medicinal property by following stringent and traditional method of preparation. Objectives: Therefore, the present study is designed to evaluat...
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