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IN-VITRO ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITY OF POLYALTHIA LONGIFOLIA (SONN.) THWAITE SEEDS
The present study is designed to evaluate the in vitro antioxidant and in-vivo anti-inflammatory activities of Polyalthia longifolia (Sonn.) Thwaite seeds. Initially, the extracts (Nonpolar to polar) were screened for in-vitro antioxidant activity by DPPH, nitric oxide radical, hydroxyl radical, and superoxide radical considering ascorbic acid as standard. Among the extracts the ethyl acetate and ...
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RISK ASSESSMENT OF SOME HERBAL POWDERS AND HERBAL FORMULATIONS CONTAMINATED WITH HEAVY METALS
Ten herbal medicines, Four herb choornam (Trikatu, Hingwashtak, Triphala and sitopladi) and five herbal compounds - Kutajghan Vati, Gandhak Rasayan, Sarivadi Vati, Chanderprabha Vati, Shankh Vati were tested for levels of heavy metals (Lead, copper, cadmium, iron, chromium, manganese, nickel and zinc). Both herbal extracts and herbal formulations showed the presence of heavy metals. Concentrations...
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EXOGENOUS HYDROGEN SULFIDE (H2S) IMPROVES THE ENDOTHELIAL AND RENAL EXCRETORY FUNCTIONS IN STREPTOZOTOCIN INDUCED WKY DIABETIC RATS
Nephropathy is one of the most common microvascular complications of diabetes. Hydrogen sulfide(H2S)has been implicated in controlling the renal glomerular (vascular) and tubular functions. This study investigates the metabolism of H2S and its effect on the progression of diabetic nephropathy. Diabetes was induced in WKY rats by streptozotocin in two groups. One diabetic group received NaHS, a H2S...
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987
COMPARATIVE STUDY OF SPECIFIC ACOUSTIC IMPEDANCE AND TRANSPORT PROPERTIES OF SULFA COMPOUNDS USING ULTRASONIC VELOCITY
Measurement of ultrasonic velocity in non-aqueous solution gives information about the behavior of solution such as molecular association and disassociation. The attraction and repulsion between the molecules of the components involved show considerable effect upon the physical and chemical properties of a solution such as density, viscosity, and ultrasonic velocity. The ultrasonic velocity data c...
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QUERCETIN AMELIORATES OXIDATIVE STRESS, NEURAL DAMAGE OF BRAIN AND BEHAVIORAL IMPAIRMENT OF RAT WITH FLUORIDE EXPOSURE
Excess fluoride causing fluorosis, can enter in to brain, disturb oxidative status and induce neural damage. Quercetin, antioxidant flavonoid stabilizes oxidative milieu of brain by quenching free radicals. The present study aimed to report ameliorative effect of quercetin on NaF induced oxidative stress, histological alterations in the brain and behavioural changes of rats. Rats were divided into...
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DESIGN, SYNTHESIS AND EVALUATION OF SOME NEW ISOXAZOLES, CYANO-PYRIDINES AND 1, 5 BENZOTHIAZEPINES AS ANTIMICROBIAL AGENTS
The title compounds (7a-f), (8a-f) and (9a-f) have been prepared from chalcones (6a-f) having s-triazine nucleus. These chalcones on cyclisation with hydroxyl amine hydrochloride in the presence of alkali and malononitrile in the presence of ammonium acetate give isoxazoles (7a-f) and cyanopyridines (8a-f) respectively. Chalcones (6a-f) on condensation with 2-amino thiophenol in the presence of gl...
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ESTIMATION OF NELFINAVIR MESYLATE IN PHARMACEUTICAL DOSAGE FORM BY SPECTROFLUORO- PHOTOMETRY
A new specific, selective and inexpensive spectrofluorophotometric method has been developed for determination of Nelfinavir mesylate in bulk drug and its dosage form. Fluorescence spectrum of Nelfinavir mesylate in methanol showed excitation wavelength at 253 nm and emission wavelength at 508 nm. The calibration curve for Nelfinavir mesylate was found to be linear over the concentration range of ...
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A NOVEL, SENSITIVE, BIOANALYTICAL METHOD FOR ESTIMATION OF AMLODIPINE BESYLATE IN RAT PLASMA USING FLOURESCENCE DETECTION BY RP-HPLC
The aim of the present work was to develop and validate a novel, rapid, sensitive, accurate and specific RP-HPLC assay with fluorescence detection for the quantification of amlodipine besylate in rat plasma to be applied to preclinical studies. Flourescein was used as internal standard (IS) and the detection was carried out by an online wavelength switching which enabled detection of amlodipine &a...
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STUDIES ON ABOVE GROUND BIOMASS (AGB) FOR ASSESSING VEGETATION CARBON POOL IN TROPICAL FOREST ECOSYTEM OF CENTRAL INDIA
For estimation of carbon stocks in tropical forest types belonging to southern part of Madhya Pradesh, 30 adopted representative sites comprising eight districts viz, Jabalpur, Seoni, Balaghat, Narsinghpur, Mandla, Dindori, Shahdol and Umaria were selected for study and studies were carried out during 2009 to 2011. The study covered three types of vegetation i.e. teak mixed forest, sal mixed fores...
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AN INVESTIGATION ON THE TYPE I ANTIDIABETIC ACTIVITY OF METHANOLIC EXTRACT OF MARINE ALGAE, GRACILARIA EDULIS AND SARGASSUM POLYCYSTUM
The objective of this study was to evaluate the antidiabetic activity of methanolic extract of marine algae Sargassum polycystum (MSP) and Gracilaria edulis (MGE) in STZ induced diabetes in rats for Type I diabetic mellitus. The marine algae SP and GE were dried under shade and then powdered, and extracted with methanol. Preliminary phytochemical studies and acute toxicity studies were also carrie...
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