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IMPACTS OF HIGH DIETARY FAT ON SERUM CHOLESTEROL AND DEVELOPMENT OF FATTY LIVER IN RATS
The present study was designed to evaluate the impacts of high dietary fat on serum Total cholesterol and fatty liver syndrome in rats. Rats are fed on diets containing cholesterol; they develop fatty livers which are characterized by the presence in the liver of excessive amounts of cholesteryl esters, and glyceride. Increasement of glyceride content depend on a number of factors, such as the d...
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EVALUATION OF ANTIMICROBIAL ACTIVITIES AND DNA-BINDING PROPERTIES OF MOLYBDENUM COMPLEXES
Molybdenum is a trace element distributed widely in nature which plays an important role in plant and animal nutrition and in our industrial society. Molybdenum is essentially present in the enzymes nitrogenase, Xanthine-oxidase, sulphite oxidas, nitrate reductase, formate dehydrogenase and aldehyde oxidase. These enzymes are responsible for a number of catalytic reactions of redox nature. M...
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1609
STUDY OF THE ANTICONVULSANT ACTIVITY OF ETHANOLIC EXTRACT OF RHIZOMES OF ZINGIBER OFFICINALE IN EXPERIMENTAL ANIMALS
Objective: To evaluate the anticonvulsant property of Zingiber officinale as well as its interaction with conventional anticonvulsant drug using Maximal electroshock seizures (MES) model and to evaluate possible mechanism involved in its action. Method: The present study was done after getting ethical clearance. The rhizomes of ginger were authenticated and extraction of dried rhizomes was done by...
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1533
ANTI-OXIDATIVE, ANTIBACTERIAL ACTIVITY AND PHYTOCHEMICAL SCREENING OF ARTOCARPUS HETEROPHYLLUS SEED EXTRACTS
Artocarpus heterophyllus is an evergreen tree cultivated and consumed throughout Nepal; however, its seed has been neglected as compared to the fruit. The sample was screened for phytochemical evaluation, and general tests, DPPH activity, antibacterial activity, and total flavonoid content was also measured. Also, the potential of its use as functional food was highlighted. Phytochemical analysis ...
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1800
ANTIMICROBIAL POTENTIAL OF SOME INDIAN MEDICINAL PLANTS AGAINST DRUG-RESISTANT PATHOGENS
Many infectious diseases are known to be treated with herbal remedies throughout the history of mankind. Even today, plant materials continue to play a major role in primary health care as therapeutic remedies in many developing countries. Traditional system of medicine is found to have utilities as many accounts. Due to population rise adequate supply of drug and high cost of treatment in side ef...
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1689
ROLE OF SOLVENT ACCESSIBLE SURFACE AREA (ASA+) AND BALABEN 3D INDEX (J3D) IN BINDING AFFINITY OF TIBO DERIVATIVES
In present QSAR study of TIBO derivatives, aim of the author is to analysis some different 3D parameter in order to get best QSAR model, which enhance the binding affinity of TIBO derivatives. Solvent accessible surface area (3D) of all atoms with positive partial charge (strictly greater than 0) and Balaben 3D index plays vital role in this concern. This study focuses on some important and differ...
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1635
WOUND HEALING POTENCY OF ETHANOLIC EXTRACT OF LEUCAS URTICIFOLIA IN EXPERIMENTAL ANIMALS
The present study was planned to investigate the effect of ethanolic extract of Leucas Urticifolia on resutured incision, excision and burn wounds in Wistar rats. Resutured incision, excision and dead space wounds were inflicted under light ether anaesthesia aseptically. In incision wound model the control animals receive only distilled water and all test animals were treated with different doses ...
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1578
DIFFERENT TYPE OF CELL DEATH INDUCTION BY CURCUMIN, ARSENIC TRIOXIDE AND DEGRASYN (WP1130) IN HUMAN MULTIPLE MYELOMA CELLS
Curcumin has been shown to inhibit the activation of nuclear factor-κB (NF-κB), which is closely linked to chemo-resistance, in multiple myeloma cells. Malignant cells of this kind typically develop progressive multidrug resistance. Our aim was to investigate new possibilities for overcoming this resistance by suppressing cell signaling pathways. MTT-dye reduction assay was used to evaluate the ...
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1565
A STUDY ON THE PREVALENCE AND MACROBIOTIC APPROACH OF CANCER AMONG THE MALE TRIBAL POPULATION OF SHILLON
Incidence of cancer in northeast is the highest in India. Nutrition intervention plays a vital role in the management of postponement of cancer. Objectives: To find out the prevalence rate of different types of cancer among the selected male tribal population of Shillong and dietary habits of these tribes the present study was carried out. Methods: Three hospitals from the city of Shillong was fol...
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1627
APPLICATION AND COST-EFFECTIVENESS OF LAMP (LOOP-MEDIATED ISOTHERMAL AMPLIFICATION) TECHNOLOGY FOR AUTHENTICATION OF MEDICINAL PLANTS PODOPHYLLUM HEXANDRUM ROYLE
We have developed a novel LAMP-based molecular marker for easy and fast identification of Podophyllum hexandrum Royle (Indian May apple). It is an important medicinal plant valued all over the world. It have both anti-cancer (pro-oxidant ability) and radioprotective (antioxidant ability) effects respectively. The LAMP-based molecular was constructed based on genomic DNA of P. hexandrum that amplif...
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