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A STUDY ON HEPATOPROTECTIVE ACTIVITY OF ETHANOL EXTRACT OF ZANTHOXYLUM ARMATUM DC (MUKTHRUBI) LEAVES IN EXPERIMENTAL ANIMAL
Zanthoxylum armatum is administered as a hepatoprotective agent during indigestion and hepatic related diseases by traditional healers. So, the aim of this study was to investigate the hepatoprotective activity of ethanol extract of Z. armatum (ZAE) in Paracetamol induced hepatotoxicity in albino rats in comparison with the activities of the known and potent hepatoprotective standard drug Silymari...
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COMPARATIVE ANTIOXIDANT POTENTIAL OF AQUEOUS AND ACETONE / WATER EXTRACTS OF GRAINS AND BRANS OF GRANIFEROUS SORGHUM [SORGHUM BICOLOR (L.) MOENCH] HYBRID GUANIPA 71 IN VITRO
Sorghum is an important food source with substantial nutritional value. An in vitro antioxidant evaluation of different extractions of graniferous sorghum [Sorghum bicolor (L.) Moench] hybrid Guanipa 71 was proposed here. Acetone / water extracts of both grains and brans revealed strong antioxidant properties by reducing Fe3+ (22.9% and 42.3%) and chelating Fe2+ (47.3% and 32.4%), respectively. Mo...
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IMPORTANT HUMAN GENES: THEIR LENGTH, LOCATION, PRODUCT, IMPORTANCE IN PROPER BODY FUNCTIONING AND INVOLVEMENT IN GENETIC DISORDERS
There are up to 25000 genes encoded by our genome however among them only some are being expressed on mass level. Some of these important genes are; ABO genes located at chromosome number 9, ALB genes located at chromosome number 4, BCL-2 genes located at chromosome number 18, CCR-5 genes located at chromosome number 3, CD4 genes located at chromosome number 12, CD8 genes located at chromosome num...
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NEUROPROTECTIVE EFFECT OF CURCUMIN WITH A FIXATOR OF ABSORPTION AGAINST BOTH ALUMINIUM NEUROTOXICITY AND ALZHEIMER’S DISEASE (EXPERIMENTAL STUDIES IN MICE)
The versatility of Aluminium chemistry will ensure its burgeoning use in the future in all manner of applications. This very same chemistry will also ensure its increased biological availability in all biota including Man. We do not know enough about the biological chemistry of a chronic and sub-acute exposure to Aluminium to be able to predict its impact on human health. Although the hypothesis o...
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A STUDY ON THE EFFECT OF ISOBARIC HYPOXIA ON ANTIOXIDANT ENZYME ACTIVITY AND LIPID PEROXIDATION IN RAT BRAIN
In the present work, an attempt was made to study the effect of isobaric hypoxic hypoxia (10%) on rat brain. Since literatures support generation of free radicals during post ischemic/hypoxic period, here hypoxia followed by reoxygenation is dealt with as the single problem. Subsequently, as brain shows regional variations in its function and metabolic activities an attempt was made to study effec...
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ASSESSMENT OF CYTOTOXICITY, ANTIOXIDANT AND FREE RADICAL SCAVENGING ACTIVITIES OF THE ETHYLACETATE EXTRACT OF CALLIANDRA PORTORICENSIS ROOT BARK
Calliandra portoricensis a medicinal plant, is widely use in the treatment/management of various diseases in Nigeria. The ethyl acetate extract of the Calliandra portoricensis root bark were tested to evaluate the cytotoxicity, antioxidant (in vitro) and free radical scavenging activity. The different assay methods, including total antioxidant activity, free radical (nitric oxide, hydroxyl radical...
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ON SOME TOPOLOGICAL INDICES OF TRIANGULAR SILICATE AND TRIANGULAR OXIDE NETWORKS
A topological index is a numeric quantity from the structural graph of a molecule. It has become a very useful tool in the prediction of pharmacological, toxicological and physico - chemical properties of a compound. In this paper, we have computed some topological indices of triangular silicate TsL (n) and triangular oxide TOL (n) networks....
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POSTMENOPAUSAL OSTEOPOROSIS- AN UPDATED REVIEW
Osteoporosis is a major growing public health problem with impact that crosses medical, social, and economic lines. Osteoporosis in older women is the 2nd most cause of death in America thus it is one of the essential area to be understand in medical science and need to update time to time. The objective of the present review is to update all aspect of osteoporosis in postmenopausal women, includi...
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IMPACT OF TEACHING CLINICAL ASPECTS OF CARDIOVASCULAR PHARMACOLOGY AT BEDSIDE
Introduction: Medical students of present era have to prove their efficiency in every step of life. To do so one has to become a competent doctor. This is possible only with the proper knowledge and application of the rational therapeutics in clinical practice. This can happen when the students are motivated and taught medicine in such a way that can produce better learning. The clinical aspect of...
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POTENTIAL DRUG CANDIDATES FOR TREATMENT OF COVID-19
The late December of 2019 witnessed an outbreak of viral pneumonia of unknown etiology (VPUE) in the Wuhan city of Hubei province, China. Later it was identified as a novel strain of β-genus Coronavirus, which is similar to the Severe Acute Respiratory Syndrome (SARS) virus, which was a global pandemic during 2002-03. This novel coronavirus is rapidly spreading with an R0 of 2 and has an incubati...
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