Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
SYNTHESIS, CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF NOVEL THIOPHENE ACRYLATE DERIVATIVES
This study deals with the synthesis and evaluation of antimicrobial activity of some novel Thiophene acrylate compounds. Totally fourteen compounds have been synthesized with different heterocyclic moieties on the Thiophene acrylate in order to study their influence on the antimicrobial activity. These compounds demonstrated potent to weak antibacterial activity against Gram-positive bacteria...
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SCHWANNOMA PRESENTING AS A GYNAECOLOGICAL MASS WITH PREGNANCY- A CASE REPORT
Schwannomas are usually benign tumors that result from the proliferation of the perineural cells. Since these tumors are very rare, misdiagnosis is common. Clinically, these tumors may present as a cranial neuropathy, abdominal or soft tissue mass, intracranial lesion, or with spinal cord compression. Histologically, these tumors are encapsulated, highly vascular, and composed of a homogenous patt...
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CLINICAL EFFECTIVENESS OF GLUCOSAMINE AND CHONDROITIN SULPHATE IN TREATMENT OF OSTEOARTHRITIS
Osteoarthritis is a form of arthritis, and is the most common form of arthritis. Persons suffering from osteoarthritis have symptoms of pain, stiffness, decreased range of motion of affected joints. Although NSAIDS are the most commonly prescribed agents for this disorder but can cause of serious adverse effects. Two compounds Glucosamine and chondroitin which are extracted from animal products ha...
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2038
COMPARATIVE STUDY OF ANTIBIOTICS FOR THEIR ANTIMICROBIAL SUSCEPTIBILITY IN CLINICAL ISOLATES
Objective: Antibiotics resistance patterns for many bacteria have changed significantly; causing poor clinical outcomes. The objective of the study was to measure the susceptibility of different antibiotics against specific clinical isolates for surveillance purpose. Method: Kirby-Bauer disc diffusion method was used to evaluate the susceptibility pattern of four antibiotics (commercially availabl...
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HOMOLOGY MODELLING, SECONDARY STRUCTURE PREDICTION AND PHYLOGENETIC COMPARATIVE ANALYSIS OF PHOSPHOLIPASE A2FROM DIFFERENT ORGANISMS
Phospholipase A2 is the enzyme that catalyzes the hydrolysis of the sn-2 fatty acyl bond of phospholipids, liberating free fatty acids and lysophospholipids. These enzymes are found in mammalian tissues, insects, reptiles, urochordates, invertebrates and echinoderms. Some of the PLA2 are toxic in nature. Venom from snakes and insects is largely composed of melittin, which is a stimulant of PLA2...
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SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF N-ARYLQUINOXALIN-2-AMINES BEARING BENZIMIDAZOLE DERIVATIVES
In the present study reports synthesis and development of 3-Chloro – N - ((5-chloro-1-tosyl-1H-benzo [d] imidazol – 2 - yl) methyl) - N arylquinoxalin-2-amines (5a-e) from 3-chloro-N-p-tolyl quinoxalin -2-amine (3) condensed with proporgyl bromide followed by adding 4-chloro-N1-tosylbenzene-1,2-diamine,by adopting simple procedure. All titled compounds were screened for their anti bacterial ac...
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ANTIMICROBIAL ACTIVITY OF AMYCOLATOPSIS ORIENTALIS JAR10 FROM AGRICULTURAL FIELD
Actinomycetes are versatile and prolific source of microbial natural products with great advantage in medicine and agriculture. Recently there is growing interest in exploring biological active compounds from rare actinomycetes. Usually rare actinomycetes are regarded as strains of actinomycetes whose isolation frequency by conventional methods is much lower than that of Streptomycetes strains. ...
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SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF N-{4-[(6-CHLORO-4-OXO-4H-CHROMEN-3-YLMETHYLENE) IMINO] PHENYL}-2-(SUBSTITUTED PHENOXY ACETAMIDE) DERIVATIVES
Some N-{4-[(6-chloro-4-oxo-4H-chromen-3-ylmethylene) imino] phenyl}-2-(substituted phenoxy) acetamide derivatives (3) were synthesized by reacting N-{4-[(6-chloro-4-oxo-4H-chromen-3-ylmethylene) imino] phenyl}-2-chloroacetamide (2) with some substituted phenol in dry acetone in the presence of K2CO3 and catalytic amount of KI. The chemical structures of the compounds were elucidated by IR, 1H-NMR ...
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DEVELOPMENT AND VALIDATION OF HPTLC METHOD FOR ESTIMATION OF FLUOXETINE IN ITS CAPSULE FORMULATION
An HPTLC method for estimation of Fluoxetine in its capsule formulation has been developed. It employs aluminium backed silica gel 60 F254 TLC plates, (20 cm × 10 cm, layer thickness 0.2 mm) prewashed with methanol and mobile phase comprising of toluene: 2-propanol: ammonia 2:2:0.4 (v/v/v). The developing solvent was run upto 80 mm in Camag chamber previously saturated with 10.0 mL of solvent mix...
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ORTHOSIPHON STAMINEUS INCREASES METABOLISM OF AMINOPYRINE IN FEMALE RAT HEPATOCYTES BY INHIBITING PROTEIN KINASE- A
Orthosiphon stamineus (Family: Lamiaceae) has becoming one of the popular medicinal plants in Malaysia due to its high beneficial effects in treating diabetes mellitus, hypertension and kidney stones. The present study was conducted to evaluate the mechanism of O. stamineus in affecting metabolism of aminopyrine in female rat hepatocytes via second messenger pathway. Liver perfusion was used to is...
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