Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
PREPARATION OF CARBAPOL COATED NANOPARTICLES BY EMULSION POLYMERIZATION TECHNIQUE
Nowadays there has been considerable interest in developing new routes alternative to injection for delivering macromolecules such as proteins and peptides. However, peptides and protein drugs are degraded before they reach the blood stream and can not cross the mucosal barrier. The mucoadhesive polymer coated nanoparticles can solve these problems. They were prepared by emulsion polymerization. M...
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1357
SUBTRACTIVE GENOMICS APPROACH FOR IN SILICO IDENTIFICATION OF NOVEL DRUG TARGETS AND EPITOPES FOR VACCINE DESIGN IN TREPONEMA PALLIDUM SUBSP. PALLIDUM STR. NICHOLS
In silico differential genomics helps to identify genes that encode for unique metabolism with relation to human. The genomic database provides a vast amount of useful information for the drug target identification. The subtractive dataset obtained comparatively between the human and the pathogen genome, differentially provides information about the genes that are likely to be essential to the pat...
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1585
FORMULATION AND EVALUATION OF IMMEDIATE RELEASE TABLET OF LAMIVUDINE, ZIDOVUDINE AND NEVIRAPINE
The present study outlines a systematic approach for Formulation and Evaluation of Immediate release Tablets of lamivudine and Zidovudine , Nevirapine- HAART triple therapy. The objective of this regimen is, To delay disease progression, To increase the duration of survival by achieving maximal and prolonged suppression of HIV replication, To restorate and preserve immunological function. Combinat...
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1635
HPTLC QUANTIFICATION OF N-OCTACOSANOL IN TINOSPORA CORDIFOLIA MIERS. STEM OBTAINED FROM DIFFERENT GEOGRAPHICAL SOURCES
n-octacosanol is a normolipidemic aliphatic primary alcohol obtained from the plant Tinospora cordifolia Miers. In the present study, the plant stems were collected from five accessions namely Anniyalam, Chennai, Hassan, Vishakhapatnam and Bangalore between June and August. Later a simple HPTLC method has been established for determination of n-octacosanol in methanolic extracts of all these geogr...
3474
1643
FORMULATION AND EVALUATION OF ONCE DAILY MATRIX TABLETS OF METOPROLOL SUCCINATE USING HYDROXYPROPYL METHYL CELLULOSE BY WET GRANULATION TECHNIQUE
The aim of the current study was to develop once-daily sustained-release matrix tablets of metoprolol succinate, Selective β1- blocker used in cardiovascular diseases. The tablets were prepared by the wet granulation method. Ethanolic solutions of ethylcellulose (EC), polyvinylpyrrolidone K30 were used as granulating agents along with hydrophilic matrix polymer hydroxypropyl methylcellulose (HPMC...
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PREPARATION AND EVALUATION OF MUCOADHESIVE MICROCAPSULES OF SODIUM VALPROATE
Mucoadhesive microcapsules of sodium valproate, an anticonvulsant used in the treatment of epilepsy and in migraine, have been prepared from sodium alginate, hydroxypropylmethyl cellulose-K4M, carbopol 934P & sodium CMC using 10% w/v calcium chloride solution by ionic gelation method. Drug: polymer ratios were 1:1 in all the formulations and polymer mixtures employed were 4:1, 5:1, 6:1, 7:1 ...
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1524
STUCTURAL AND SPECTROSCOPIC STUDY OF Cu(II) – TAURINE –HEXAMINE TERNARY COMPLEX: DETERMINATION OF THE STABILITY CONSTANTS IN METHANOL – WATER MIXTURES
Stoichiometry and apparent stability constant (KC) of the complex formed between Cu(II), hexamine and taurine were determined in water and methanol-water mixtures (% methanol w/w: 3.11; 6.15; 10.4; 15.2; 19.9 and 25.3) by UV–vis spectroscopy at 25o C and constant ionic strength (0.05 M, sodium chloride). Stoichiometry of the ternary complex (1:1: 2, metal: hexamine: taurine) is not modified with...
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1702
DEVELOPMENT OF INTEGRATED INDUSTRIAL PROCESS LAYOUT DESIGN FOR THE PRODUCTION AND QUALITY CONTROL FACILITY OF VARIOUS PHARMACEUTICAL FORMULATIONS
Objectives: To develop an integrated industrial production and quality control layout which facilitates the pharmaceutical industries for manufacturing, controlling quality of various types of pharmaceutical formulations in a single production unit. Methods: For designing the integrated process layout for the production and quality control, different operations and their sequences involved in t...
5382
2031
ANTIOXIDANT POTENTIAL OF THE WHOLE PLANT EXTRACT OF MOLLUGO PENTAPHYLLA LINN. ON ETHANOL INDUCED LIVER DAMAGE
The potential antioxidant effect ethanol induced liver damage was investigated using crude methanolic extract of the whole plant of Mollugo pentaphylla Linn. The standard drug used was ascorbic acid mg / kg/day. Serum cholesterol, triglycerides aspartate amino transferase (AST) and alanine amino transferase (ALT) levels were measured as antioxidant indicators. There was a significant reduction...
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PRIMARY FALLOPIAN TUBE ADENOCARCINOMA: A CASE REPORT
Purpose: Primary fallopian tube carcinoma (PFTC) is a rare tumor that histologically and clinically resembles to epithelial ovarian cancer (EOC). The purpose of this study is to present a case history, treatment & review the current available literature on PFTC. Material, methods and results: Early clinical presentation and prompt investigation often lead to diagnosis at an early stage. The...
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