Most Cited
Year | 2020 | 2021 | 2022 | Total |
---|---|---|---|---|
No. of Published Articles | 745 | 760 | 548 | 2053 |
Citations | 699 | 263 | 21 | 983 |
Projected Impact Factor | 3.76 | 2 | 0.64 |
MODIFIED RELEASE FORMULATIONS TO ACHIEVE THE QUALITY TARGET PRODUCT PROFILE (QTPP)
Modified Release (MR) Formulations have a modification in the release mechanism. Modified release dosage forms are developed by altering drug absorption or the site of drug release in order to achieve predetermined clinical objectives. Modified drug release from dosage forms is complemented by the allied processes of drug design, of dosage administration, and of membrane transport and absorption o...
9570
1877
PHYTOCHEMICAL SCREENING AND DIURETIC ACTIVITY OF ALLIUM SATIVUM STEROIDAL AND TRITERPENOID SAPONIN FRACTION
Allium sativum L. (Liliacea) is a perennial bulb with a tall, erect flowering stem. The bulb of the plant has been used in many parts of the world as a stimulant, carminative, antiseptic, expectorant, anthelmintic and diuretic. This study has been planned to assess the diuretic activity of fresh garlic bulb extract targeting the steroidal and triterpenoidal saponin content. The rats were randomly ...
5908
1402
ESTIMATION OF TOTAL POLYPHENOLIC CONTENT IN AQUEOUS AND METHANOLIC EXTRACTS FROM THE BARK OF ACACIA NILOTICA
Plant polyphenols have been studied largely because of the possibility that they might underlie the protective effects afforded by fruit and vegetable intake against cancer and other chronic diseases. The objective of the present study is to estimate the total polyphenolic content in aqueous and methanolic extract prepared from the bark of Acacia nilotica plant species. Acacia nilotica (L.) Willd....
3552
1242
EVALUATION OF ANTI-MICROBIAL ACTIVITY AND WOUND HEALING OF KEFIR
Objective: Pseudomonas aeruginosa has emerged as an important cause of serious wound infection and death in burn patients. There are a limited numbers of antimicrobial agents affecting the bacterium due to its inherent resistance. Kefir is a natural probiotic which contains diverse spectrum of bacteria, yeasts and their metabolites with potential antimicrobial activity. Current study was designed ...
4709
1369
A STUDY ON PRELIMINARY PHYTOCHEMICAL AND DIURETIC ACTIVITY OF BARK OF THESPESIA POPULNEA
Thespesia populnea is a reputed ever green tree belonging to the family malvaceae; commonly known as Indian tulip tree. The plant is distributed tropical regions and coastal forest in India. It is well known and all the parts are used in traditional system of medicine. The plant has been used as astringent, antibacterial, hepatoprotective, haemostatic, anti-diarroheal and anti-inflammatory. The sh...
4304
1432
STUDY OF PHYTO CHEMICAL, ANALGESIC AND ANTI ULCER ACTIVITY OF EXTRACTS OF AERIAL PARTS OF CARDIOSPERMUM HALICACABUM LINN.
The dried aerial parts of Cardiospermum halicacabum Linn were subjected to extraction using the solvents (petroleum ether, chloroform, Ethyl acetate and ethanol) in increasing order of polarity. The prepared extracts were then subjected to preliminary phytochemical analysis. It was found plant possesses carbohydrates, alkaloids, sterols, flavanoids and saponins. All extracts were selected for furt...
2929
1279
ENHANCEMENT OF ANTIBACTERIAL ACTIVITY OF AMOXICILLIN BY SOME GHANAIAN MEDICINAL PLANT EXTRACTS
As part of our ongoing study to screen local herbs for their possible usefulness as anti-infectives, we assessed extracts from 16 medicinal plants for their antibacterial properties and their influence on the activity of amoxicillin. The minimum inhibitory concentrations (MIC) of amoxicillin against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli and Salmonella t...
3940
1376
ASPECTS OF VALIDATION IN HPLC METHOD DEVELOPMENT FOR PHARMACEUTICAL ANALYSIS – COMPARISON OF VALIDATION REQUIREMENTS BY FDA, USP AND ICH
The most important factor in developing pharmaceutical drug substances and drug products today is ensuring that the HPLC analytical test methods that are used to analyze the products generate reliable, reproducible and meaningful results. The US Food and Drug Administration (FDA) and United States Pharmacopeia (USP) have each documented the importance of this to the drug development process and ha...
8695
1991
DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR QUANTITATIVE ESTIMATION OF RITONAVIR IN BULK AND PHARMACEUTICAL DOSAGE FORMS
A simple, precise, specific and accurate reverse phase HPLC method has been developed for the determination of Ritonavir in bulk and pharmaceutical dosage forms. The chromatographic separation was achieved on Symmetry C18 (4.6 x 100mm, 3.5 μm) column using a mixture of Buffer: Acetonitrile (50:50) as the mobile phase at a flow rate 1.0 ml/min. Linearity was observed in concentration range of 50-1...
2951
1038
DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR QUANTITATIVE ESTIMATION OF RITONAVIR IN BULK AND PHARMACEUTICAL DOSAGE FORMS
A simple, precise, specific and accurate reverse phase HPLC method has been developed for the determination of Ritonavir in bulk and pharmaceutical dosage forms. The chromatographic separation was achieved on Symmetry C18 (4.6 x 100mm, 3.5 μm) column using a mixture of Buffer: Acetonitrile (50:50) as the mobile phase at a flow rate 1.0 ml/min. Linearity was observed in concentration range of 50-1...
4099
1315