Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
SCHIFF BASE: A REVIEW OF PHARMACOLOGICAL ACTIVITIES
Schiff bases are generally aldehyde or ketone-like compounds in which an imine or azomethine group replaces the carbonyl group. They are versatile and exhibit a broad range of pharmacological activities as antimicrobial, antibacterial, antifungal, antiviral, and anticonvulsant. Anti-cancer activity has been used widely for industrial purposes or therapeutic use. Thus, Schiff bases are highly desir...
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AN UPDATED STATUS OF ALANINE RACEMASE INHIBITORS: A REVIEW
Enzyme Alanine racemase is well known for performing a predominating role in mycobacterium cell wall synthesis. D-alanine provided by Alanine racemase serves as a peptidoglycan precursor, utterly vital for maintaining the growth and integrity of the cell wall. The lipid-rich mycobacterium cell wall is prevalent amidst prokaryotes with immense potential of becoming a therapeutic target for new drug...
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MOLECULAR DOCKING STUDY OF HEMAGGLUTININ PROTEIN OF INFLUENZA A VIRUS TO DEVELOP A NOVEL ANTI-INFLUENZA DRUG
The Hemagglutinin (HA) protein of the Influenza virus plays a vital role in viral replication. In this study, numerous small molecules were screened systematically against the HA protein to find a compound that can bind to it selectively. The HA protein’s three-dimensional crystal structure was obtained from RCSB PDB and inputted into the FTMap Web Tool to identify the best possible drug gable h...
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HERBAL BASED ANTI-MICROBIAL BOOSTER FOR THE TREATMENT OF RESISTANT MYCOBACTERIUM TUBERCULOSIS
Persistent Mycobacterium tuberculosis (Mtb) attributable to resistant strains has increased the burden leading to poor quality of life to the patients. Drugs of herbal origin have been identified as potential sources of new anti-tubercular agents for the treatment of this disease and emerging resistant strains of the bacterium. In this research, therefore, five herbs/plants that have been indicate...
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DIURETIC ACTIVITY OF ETHANOLIC EXTRACT OF IMPERATA CYLINDRICAL (L.) P. BEAUV. (POACEAE) LEAVES ON RAT
This work aimed to evaluate the diuretic activity of Imperata cylindrica (Poaceae) leaves on rat. The extract was administered orally at doses 100, 200 and 400 mg/kg. The 24h urine volume and its pH were measured, natriuresis and kaliuresis were dosed. The results show that I. cylindrica increases diuresis, natriuresis and kaliuresis, but doesn’t affect urine pH. Diuresis of 24 h urine increases...
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ANTI-ULCER ACTIVITY OF POLYHERBAL FORMULATION ACIDEZ IN EXPERIMENTALLY INDUCED GASTRIC ULCERS IN RATS
Aim and Objective: Acid-related health problems mostly affect the quality of life and are a major factor in morbidity and mortality in patients. This study is designed to evaluate the anti-ulcer activity of Polyherbal formulation ACIDEZ against experimentally induced gastric ulcers in rats. Methodology: To determine anti-ulcer activity, ulcers were induced by aspirin plus pylorus ligation and acet...
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SCREENING OF PGPR TRAITS AND MONOCROTOPHOS PESTICIDE DEGRADATION PROPERTIES OF ACTINOBACTERIAL ISOLATES
Bioremediation of organic compounds and heavy metals has been recognized to be a successful and effective technique in rhizoremediation of soil toxicity using the beneficial microbes which produce different metabolites and enzymes to degrade the toxic compounds/ pesticides available in the soil. In the present study, actinobacterial isolates were explored and identified for bioremediation of soil ...
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NATURAL ALKALOIDS AS POTENTIAL ANTIMALARIAL DRUGS FROM BAUHINIA PURPUREA LEAVES -AN IN-SILICO APPROACH
Malaria is the most important parasitic disease in humans, with transmission occurring in over 100 countries with a population of three billion people. Protozoan parasites of the genus Plasmodium cause it. These parasites are transmitted from one person to another by the female anopheles mosquito. Medicinal plants possess many phytochemicals of great therapeutic value, and many effectively kill ma...
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PHARMACOGNOSTICAL, PHYTOCHEMICAL AND PHARMACOLOGICAL STUDIES ON TUBER OF PUERARIA TUBEROSA
Medicinal herbs have an important role in illness prevention, and their promotion and usage are compatible with all current disease preventive techniques. Pueraria tuberosa, widely known as kudzu, is a climber with tuberculated woody stems. It has exhibited Cardio-tonic, Aphrodisiac, Abthyperglycemic Galactogogic, and anti-lipidemic characteristics Daidzin, Puerarin, Puerarone, Genistein, Puetuber...
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AMELIORATIVE EFFECT OF KALYANAKGHRITA (KG) ON WITHDRAWAL SYMPTOMS IN ALCOHOL-DEPENDENT MICE
Introduction: Alcohol de-addiction is challenging due to the severe alcohol withdrawal symptoms. This article reports ameliorative effect of KalyanakGhrita (KG) on ethanol withdrawal symptoms in animal model. Material and Methods: After approval from Animal Ethics committee, alcohol dependence was developed in pre Rota road trained Swiss mice by intermitted access of 20% ethanol in 14 days. After ...
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