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THE EFFICACY OF CUCURBITANE TYPE TRITERPENOIDS, GLYCOSIDES AND PHENOLIC COMPOUNDS ISOLATED FROM MOMORDICA CHARANTIA: A REVIEW
Momordica charantia Linn. which has been used mainly for edible purposes at different countries of the world including South East Asia and has also been extensively used in traditional medicines for the cure of various ailments. M. charantia belongs to the cucurbitaceae family. Extensive research has been carried out on the fruit, leaves, and seeds of the plant. Most importantly, all these researc...
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MOLECULAR CHARACTERIZATION OF PSEUDOMONAS AERUGINOSA ISOLATES RECOVERED FROM HUMAN PATIENTS IN HIMACHAL PRADESH (INDIA) FOR SELECTIVE GENES: EXTENDED SPECTRUM β-LACTAMASE (ESBL), AMPICILLIN CLASS C (AMPC) AND METALLO β-LACTAMASE (MBL) GENES
The present study highlights the occurrence of β-lactamase (bla) genes belonging to different classes: extended spectrum β-lactamase genes (blaTEM, blaSHV, blaCTX-M and blaPER), metallo β-lactamase genes (blaNDM and blaGIM and Ampicillin class C genes (blaPDC and blaCMY) in P. aeruginosa isolates by PCR amplification. The isolates were recovered from human patients of Indira Gandhi Medical Coll...
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NUTRITIONAL AND PHARMACOLOGICAL IMPORTANCES OF GENUS COSTUS: A REVIEW
The Genus Costus (Linn.) is an important medicinal plant belonging to the family Costaceae. The Genus as a whole is often called Spiral Ginger. The genus is represented by about 175 species distributed throughout the world. The aerial parts of the plant and the rhizomes are edible, the rhizome being good source of carbohydrate, starch, amylase, protein and lipid. Moreover the rhizome is an alterna...
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EXTRACTION AND CHARACTERIZATION OF THE GUM ISOLATED FROM ARAUCARIA HETEROPHYLLA
Objective: Nature has given ginormous resources to mankind since time immemorial. Amidst of various natural sources, products from plant origin endure more of commercial importance. Gums and resins are plant based reserves occupying a prime place among Non-Wood Forest Produce (NWFP). It is a most challenging aspect to isolate and characterise eco rich gums and resins from trees which can be widely...
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ORAL DISINTEGRATING TABLETS OF CILOSTAZOL-HP-β-CD INCLUSION COMPLEX
Low solubility and biovariability associated with cilostazol (CLZ) pose serious formulation problems despite several advancements in dosage form design. The present research work amalgamates two different solubility enhancement techniques, viz. spray drying and cyclodextrin inclusion complexation to produce amorphous composites of CLZ with increased solubility and dissolution characteristics. FTIR...
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ISOLATION AND CHARACTERISATION OF STIGMAST-5-EN-3-OL (β-SITOSTEROL) FROM CALOTROPIS PROCERA LATEX ETHYL ACETATE FRACTION FOR IMMUNOMODULATORY ACTIVITY
Aim of this study was to identify and characterise the bioactive principles from the latex of Calotropis procera which could influence cellular and humoral aspects of immune system which may influence immune disorders. Calotropis procera R.Br. (Asclepiadaceae), commonly known as milk weed or swallow-wort, is a medicinal plant widely used as a folk medicine in India. It exhibits a wide spectrum of ...
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A FACTORIAL STUDY ON FORMULATION DEVELOPMENT OF EFAVIRENZ TABLETS EMPLOYING Β CYCLODEXTRIN- POLOXAMER 407- PVP K30
Efavirenz, a widely prescribed anti retroviral drug belongs to class IΙ under BCS and exhibit low and variable oral bioavailability due to its poor aqueous solubility. Its oral absorption is dissolution rate limited and it requires enhancement in the solubility and dissolution rate for increasing its oral bioavailability. The objective of the study is to evaluate the feasibility of formulating ef...
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PHARMACOGNOSTIC EVALUATION AND ANTIMICROBIAL STUDIES ON MORINGA OLEIFERA LAM. (MORINGACEAE)
The pharmacognostic evaluation, anatomy and antimicrobial potentials of the leaf, stem and root of Moringa oleifera Lam were evaluated. Powdered extracts obtained from the various plant organs were used for the analytical standardization. The methanolic plant extracts were assayed for antimicrobial activities using the Agar well diffusion method. This was compared with standard antibiotics, Gentam...
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FORMULATION AND EVALUATION OF HYDROCHLOROTHIAZIDE AND RAMIPRIL MOUTH DISSOLVING TABLET USING DIFFERENT SUPERDISINTEGRANTS
The purpose of this research was to develop mouth dissolve tablets of Hydrochlorothiazide and Ramipril, were prepared by direct compression technique. Ramipril is an Angiotensin Converting Enzyme (ACE) inhibitor. It is an inactive prodrug that is converted to ramiprilat in the liver, the main site of activation, and kidneys. Thiazides such as hydrochlorothiazide promote water loss from the body (d...
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POTENTIAL OF BRYOPHYTES AS THERAPEUTICS
Bryophytes, a small group of lower plant phylogenetically placed between algae and the vascular plants comprise of hornworts, liverworts, and mosses. They are the second largest group of land plants and extremely rich in a variety of biologically active compounds viz. terpenoids, phenols, glycosides, and fatty acids. This small slow-growing group of plants is stockroom of naturally occurring mater...
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