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A REVIEW ON DIABETIC NEUROPATHY AND NEPHROPATHY
Diabetes is a major public health problem. Diabetes mellitus now affects large number of people in many developing countries than western countries where only two or three percent of the population is affected. With on estimated 33 million people in India alone affected by diabetes. It is a major epidemic of the twentieth century. Diabetes is a chronic disorder, which is associated with obesity, h...
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ANTIMICROBIAL AND ANTIOXIDANT PROPERTY OF COMMONLY FOUND MICROALGAE SPIRULINA PLATENSIS, NOSTOC MUSCORUM AND CHLORELLA PYRENOIDOSA AGAINST SOME PATHOGENIC BACTERIA AND FUNGI
In the present study, three algal species (Spirulina platensis, Chlorella pyrenoidosa and Nostoc muscorum (ATCC 2789) were used to investigate their antimicrobial and antioxidant properties against some human pathogenic bacteria and fungi (Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, Bacillus subtilis, Bacillus cereus, Micrococcus luteus and fungus Aspergillus luchuensis,...
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POTENTIAL ANTIBACTERIAL AND ANTINFUNGAL ACTIVITY OF AQUEOUS EXTRACT OF CYNODON DACTYLON
The use of medicinal plants in the world and especially in India, contributes significantly to primary health care. Whole plant of the Cynodon dactylon is traditionally used to treat painful and inflammatory condition. We have undertaken this study since no detailed scientific study was available regarding the antifungal and antibacterial activity of the aqueous extract of the whole plant. In ...
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FORMULATION DEVELOPMENT AND EVALUATION OF LAMOTRIGINE SUSTAINED RELEASE TABLETS USING 32 FACTORIAL DESIGN
The main objective of present investigation is to formulate the sustained release tablet of lamotrigine using 32 factorial design. Lamotrigine, a weakly basic and anticonvulsant drug belongs to BCS Class II, having high permeability and poor solubility. The sustained release tablets of lamotrigine were prepared employing different concentrations of HPMC K4M and HPMC K100M in different combinatio...
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REGULATORY DOSSIERS OF ASEM COUNTRIES
Demonstration of safety and efficacy of the drug product for human use is important before the drug product gets approval for import or manufacturing of new drug by regulatory authority in any country. Once the clinical and preclinical data have been collected, a New Drug Application (NDA) must be submitted to regulatory authority for approval. Globalization of pharmaceutical industry has created ...
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EFFECT OF SWARNAPRASHANA ON CHILD HEALTH: A REVIEW
Introduction: Gold preparations are highly prized and often utilized for their tonic and revitalizing effects in Indian systems of medicine. Gold has both preventive and curative medicinal properties. The Kashyap Samhita, under the name Swarnaprashana, describes the usage of gold internally in children via the oral route. After birth, it is indicated in Lehan karma (supplementary feeding to improv...
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FLAVONOIDS FROM ASTRAGALUS GENUS
In this review our main focus is on flavonoid groups which are one of the main active constituents found with other active constituents like saponins and polysaccharides, while poisonous groups are nitro-compounds, indolizidine alkaloids and the seleniferous derivatives in Astragalus genus. It is well established fact that flavonoid possess many biological activity such as antiallergic, anti-infla...
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EFFECT OF LACTOSE, L-HPC GRADES ON FLOW PROPERTIES OF MICRONIZED TADALAFIL FORMULATED AS SOLID DOSAGE FORM
Tadalafil belongs to BCS class IV and recommended for treatment of erectile dysfunction. Micronization technique is used by researchers to improve its solubilization and dissolution rate. The conventional tabletting excipients pose challenge especially with micronized drug particles. The current research work aimed to study the effect of some speciality excipients on flow properties of micronized ...
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SIMULTANEOUS ESTIMATION OF NORFLOXACIN AND TINIDAZOLE IN COMBINED TABLET DOSAGE FORM BY USING RP- HPLC METHOD
Simultaneous estimation method for Norfloxacin and Tinidazole in tablet dosage form had been developed by RP- HPLC. Both the drugs come under the category of antimicrobials and prescribed frequently in combination. The developed method is a gradient method which gives retention time of Norfloxacin and Tinidazole as 3.8min and 4.8min respectively. The separation was carried out on Supelco C18 (25cm...
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ANTI-ULCER EFFICACY AND SAFETY OF ANDA LEGHYAM A POLYHERBAL SIDDHA FORMULATION
Anda leghyam (AL) a herbo-animal Siddha formulation is administered for Gunmam (Acid peptic diseases) by many Siddha physicians popularly. Anti ulcerogenic activity of the AL has been studied using Aspirin-Pylorus ligation induced gastric ulcer methods (four groups/method, n=6, Aspirin 400mg/kg, Omeprazole 10mg/kg, AL 250,500mg/kg) in wistar albino rat models. Animals were sacrificed and their sto...
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