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A REVIEW ON DIABETIC NEUROPATHY AND NEPHROPATHY
Diabetes is a major public health problem. Diabetes mellitus now affects large number of people in many developing countries than western countries where only two or three percent of the population is affected. With on estimated 33 million people in India alone affected by diabetes. It is a major epidemic of the twentieth century. Diabetes is a chronic disorder, which is associated with obesity, h...
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PHYTOCONSTITUENTS, PHARMACOLOGICAL ACTIVITIES OF MARSILEA MINUTA L. (MARSILEACEAE) – AN OVERVIEW
Herbal drugs play an important role in the treatment of much illness. The plant has tremendous biological effects and applied in the different system of traditional medication for the treatment of various diseases. Marsilea minuta is one of the most popular foreground plants for aquariums that grows about two to three inches tall in shallow water and has attractive little markings on the tiny, va...
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VIRTUAL SCREENING, SYNTHESIS OF NEWER HETEROCYCLES AS PPAR γ AGONISTS WITH ANTIDIABETIC ACTIVITY
Recent decades have experienced a sharp increase in the incidence and prevalence of diabetes mellitus. The major therapeutic approach is to diabetes is to reduce gastrointestinal glucose production and absorption through the inhibition of carbohydrate digesting enzymes such as α-amylase and α-glucosidase. The agonists of PPAR γ is of great interest to the pharmaceutical industry since they regu...
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REVIEW ON THE FIXED DOSE COMBINATION DRUGS AND THEIR INCOMPATIBILITIES
Incompatibility is an undesirable reaction that occurs between drugs, excipients, or with container. This may be therapeutic, chemical and physical incompatibility. Fixed dose combination provides challenge in product development due to incompatibility of two drugs. So severe degradation of drug in presence of each other. Formulation and stability difficulties arise with incompatible combination. ...
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PHYTOCHEMICAL AND PHARMACOLOGICAL PROFILE OF MORINGA OLEIFERA LAM.
Moringa oleifera, a miracle plant, is praised for beneficial health nutrients and has potential cholesterol-lowering activity. Almost all the parts of the Moringa oleifera plant have potential bioactivity. The main active constituents of Moringa oleifera are flavonoids, alkaloids, phenols, vitamins, minerals, proteins, glycosides, Glucosinolates and Isothiocyanates, terpenes, saponins, tannin...
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ETHNOBOTANY AND ANTIOXIDANT DETERMINATION OF PHOEBE COOPERIANA FRUIT-A HIGHLY UTILIZED WILD FRUIT IN ARUNACHAL PRADESH, INDIA
The fruit of Phoebe cooperiana U.N Kanjilal ex A. Das is highly priced and one of the most preferred folk food among the Indigenous people of Arunachal Pradesh, India. The methanol extract of fruit collected from East Siang District of Arunachal Pradesh, India were evaluated for total phenolic content, total flavonoid content and antioxidant potential. The methanol extract of fruit were subjected ...
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ADVERSE DRUG REACTION MONITORING AND REPORTING: KNOWLEDGE, ATTITUDE AND BELIEF OF PHYSICIANS & PHARMACISTS OF RAS AL KHAIMAH, UNITED ARAB EMIRATES (UAE)
Adverse drug reactions (ADR) contribute significantly in health care cost through increased patient morbidity and mortality. Thus, there is an urgent need to create awareness among health care professionals towards ADR monitoring and reporting. The aim of our study is to assess the knowledge, attitude and belief of physicians and pharmacists towards ADR. This is a prospective cross-sectional surve...
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FORMULATION DEVELOPMENT AND EVALUATION OF LAMOTRIGINE SUSTAINED RELEASE TABLETS USING 32 FACTORIAL DESIGN
The main objective of present investigation is to formulate the sustained release tablet of lamotrigine using 32 factorial design. Lamotrigine, a weakly basic and anticonvulsant drug belongs to BCS Class II, having high permeability and poor solubility. The sustained release tablets of lamotrigine were prepared employing different concentrations of HPMC K4M and HPMC K100M in different combinatio...
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FLAVONOIDS FROM ASTRAGALUS GENUS
In this review our main focus is on flavonoid groups which are one of the main active constituents found with other active constituents like saponins and polysaccharides, while poisonous groups are nitro-compounds, indolizidine alkaloids and the seleniferous derivatives in Astragalus genus. It is well established fact that flavonoid possess many biological activity such as antiallergic, anti-infla...
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ANTIMICROBIAL AND ANTIOXIDANT PROPERTY OF COMMONLY FOUND MICROALGAE SPIRULINA PLATENSIS, NOSTOC MUSCORUM AND CHLORELLA PYRENOIDOSA AGAINST SOME PATHOGENIC BACTERIA AND FUNGI
In the present study, three algal species (Spirulina platensis, Chlorella pyrenoidosa and Nostoc muscorum (ATCC 2789) were used to investigate their antimicrobial and antioxidant properties against some human pathogenic bacteria and fungi (Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, Bacillus subtilis, Bacillus cereus, Micrococcus luteus and fungus Aspergillus luchuensis,...
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