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U.V SPECTROPHOTOMETRIC METHOD FOR THE ESTIMATION OF MESALAZINE IN BULK AND ITS PHARMACEUTICAL DOSAGE FORMS
Mesalazine is used, either orally or rectally, as an anti-inflammatory agent in treating ulcerative colitis and, to a lesser extent, Crohn's disease. Mesalazine is a white to pinkish crystalline powder. It is slightly soluble in cold water and alcohol; more soluble in hot water, soluble in hydrochloric acid. A simple UV spectrophotometric method was developed for the determination of Mesalazine (M...
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DESIGN, SYNTHESIS AND EVALUATION OF ANTITUBERCULAR ACTIVITY OF AMINO AZETIDINONES FROM ISONIAZID
Azetidin-2-one analogues are reported to exhibit various pharmacological activities like cholesterol absorption inhibitory activity, human tryptase, thrombin and chymase inhibitory activity, vasopressin V1a antagonist activity, antidiabetic, anti-inflammatory, antiparkinsonian and anti-HIV activity in addition to antimicrobial.1-6 In the present study, Isoniazid (INH), the established antituberc...
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THE VALUE OF DOXYCYCLINE IN ACETIC ACID INDUCE ULCERATIVE COLITIS IN RATS
Ulcerative colitis is an idiopathic chronic inflammatory disease of the colon for which a lot of treatment modalities are present, however, significant side effects are associated with them and there is a need for a search for other treatment options. This study was aimed to investigate the therapeutic role of Doxycycline in experimentally induced colitis in rats. Animals were categorized into 5...
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DEVELOPMENT AND VALIDATION OF ANALYTICAL METHODS FOR SIMULTANEOUS ESTIMATION OF DEXTROMETHORPHAN AND QUINIDINE BY RP-HPLC AND UV-SPECTROMETRY
Objectives of study: To develop and validate new, rapid, selective, precise, accurate and economical, isocratic RP-HPLC and UV spectrophotometric method for simultaneous estimation of Dextromethorphan and Quinidine in bulk and in tablet formulations. Methods: A RP-HPLC was developed for the simultaneous estimation of Dextromethorphan and Quinidine on Phenomenex C-8 column with the mobile phase of ...
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PHYTOTHERAPY IN FUNGI AND FUNGAL DISEASE: A REVIEW OF EFFECTIVE MEDICINAL PLANTS ON IMPORTANT FUNGAL STRAINS AND DISEASES
Infectious diseases are among the most important common diseases worldwide that bring stupendous costs for human community. Medicinal plants are considered a rich source of antimicrobial agents and therefore can be used as antimicrobial remedies because of producing secondary metabolites. This article was designed to review the effective medicinal plants on fungi and fungal disease. In this study,...
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FORMULATION OF CLINDAMYCIN NANO-EMULSION
Nano-emulsions consist of fine oil-in-water or water-in-oil dispersions, having droplets covering the size range of 10 - 600 nm. The aim of this study is to formulate nano-emulsion of Clindamycin by using Emulsion Phase Inversion method and olive oil as the oil phase. Pseudo ternary phase diagram was first developed by using distilled water, olive oil and mixture of surfactants (Tween®80 and Span...
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A SURVEY ON ANTICANCER PROPERTIES OF INDIAN MEDICINAL PLANTS – A BROAD SPECTRUM ANALYSIS
Several plants across the world possess specific therapeutic and diagnostic properties. The identification of the properties among them is the most difficult task. Several researchers have used several methodologies to express the therapeutic properties in the plants. The interest of scientists among the anticancer studies has been increasing widely as cancer has become one of the deadliest diseas...
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PHYTOCHEMICAL AND ANTIOXIDANT STUDIES OF JUSTICIA GENDARUSSA BURM. F. AN ETHNOMEDICINAL PLANT
Present investigation deals with the phytochemical and antioxidant studies of Justicia gendarussa Burm.f. (family Acanthaceae), a medicinally important herb. Biochemical studies highlighted that in leaf tissue, quantities of soluble carbohydrate, amino acid and ascorbic acid are of 307 mg/g, 34.93 mg/g and 619µg/g, respectively. In stem bark, quantities of soluble carbohydrate, amino acid and a...
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VIRTUAL SCREENING, SYNTHESIS OF NEWER HETEROCYCLES AS PPAR γ AGONISTS WITH ANTIDIABETIC ACTIVITY
Recent decades have experienced a sharp increase in the incidence and prevalence of diabetes mellitus. The major therapeutic approach is to diabetes is to reduce gastrointestinal glucose production and absorption through the inhibition of carbohydrate digesting enzymes such as α-amylase and α-glucosidase. The agonists of PPAR γ is of great interest to the pharmaceutical industry since they regu...
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1912
ASSESSMENT OF NUTRITIONAL STATUS OF SCHOOL CHILDREN IN RURAL AND URBAN AREAS OF BANKURA, WEST BENGAL
The health and nutritional status of school children is an index of national investment in the development of its future manpower. Malnutrition affects the child’s physical and cognitive growth and increases the susceptibility to infections while having an adverse impact on economic growth of the country indirectly. The objective of this study is to assess the nutritional status of rural and urb...
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