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ORAL DISINTEGRATING TABLETS OF CILOSTAZOL-HP-β-CD INCLUSION COMPLEX
Low solubility and biovariability associated with cilostazol (CLZ) pose serious formulation problems despite several advancements in dosage form design. The present research work amalgamates two different solubility enhancement techniques, viz. spray drying and cyclodextrin inclusion complexation to produce amorphous composites of CLZ with increased solubility and dissolution characteristics. FTIR...
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MUCOADHESIVE BUCCAL DRUG DELIVERY SYSTEM: A REVIEW
As an alternative to injection pharmaceutical researcher and scientist are trying to explore transdermal and transmucosal route over the last few years. To overcome the deficiency associated with the other route of administration buccal region of oral cavity is an alternative target for the administration of choice of drug. The disadvantages relative with the oral drug delivery is the extensive pr...
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A REVIEW ON SOME SELECTED TRADITIONAL INDIAN MEDICINAL PLANTS OF IMMUNOMODULATORY POTENTIAL AND THEIR THERAPEUTIC USE IN RHEUMATOID ARTHRITIS
Rheumatoid arthritis is a very common auto-immune inflammatory disorder, causing disability in developed and developing countries. Conventional drugs are not only costly but are also associated with very serious adverse effects. Several Indian medicinal plants have been traditionally used for their anti-arthritic effect since time immemorial. Present review focused on the immunomodulatory potentia...
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FORMULATION AND EVALUATION OF TRANSDERMAL PATCHES OF 18-Β-GLYCYRRHETIC ACID
An attempt was made to formulate and evaluate the 18-β-glycyrrhetic acid (GA) transdermal drug delivery system. Preformulation studies on the drug 18-β-glycyrrhetic acid were done which included description, solubility and compatibility studies. Solvent casting technique was used to prepare the transdermal patches. Four formulations were made with 400mg of 18-β-glycyrrhetic acid and by using po...
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AN IDENTIFICATION OF CROP DISEASE USING IMAGE SEGMENTATION
Agriculture forms a vital part of India’s economy. More than 50% of India’s population is dependent on agriculture for their livelihood. In India, many crops are cultivated, out of which wheat is one of the most important food grains that this country cultivates and exports. Thus it can be seen that wheat forms a major part of the Indian agricultural system and India’s economy. Hence, the ma...
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DERMATOPHYTOSIS: INFECTION AND PREVENTION -A REVIEW
The growing impact of infections caused by dermatophytes i.e. Trichophyton, Microsporum and Epidermophyton is not upto the mark in their treatments via conventional methods due to resistance, side effects, and high toxicity. Over prescription and overuse of traditional antifungal agents, high side effects, less eco-friendly nature, high manufacturing costs, high management costs etc., have stimula...
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BIOACTIVITY OF MORUS ALBA L. EXTRACTS-AN OVERVIEW
Recently white mulberry has attracted a lot of interest as source of bioactive constituents used in phytopharmacy and in functional food formulation. In practice, active compounds are separated from plant material by extraction process using different solvents and extraction conditions. The most commonly solvents used for extraction are water, ethanol, methanol, acetone, ether and their mixtures. ...
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A PEDICULICIDAL ACTIVITY OF CLOVE OIL
The humans head lice are a nuisance for millions of people worldwide with high prevalence in children. Head lice have been treated by methods that include the physical removal of lice, various domestic treatments and conventional insecticides. None of these methods render complete protection and there is clear evidence for the evolution of resistance and cross-resistance to conventional insecticid...
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A STUDY ON PHYTOCHEMICAL INVESTIGATION OF DRYNARIA QUERCIFOLIA LINN RHIZOME
In the present research investigation we extracted the powdered rhizome of Drynaria quercifolia linn by Soxhletion method using different solvents. Then extracts were subjected to preliminary phyto-chemical investigation. The proximate analysis was carried out for the plant rhizome powder. The total ash value was 9.93%, Acid insoluble ash value was 4.49%, and Water-soluble ash value was 6.96% and ...
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ASSESSMENT OF KNOWLEDGE, ATTITUDE, AND PRACTICE TOWARDS EMERGENCY CONTRACEPTIVES AMONG FEMALE COLLEGE STUDENTS AT MEKELLE TOWN, TIGRAY REGION, ETHIOPIA: A CROSS SECTIONAL STUDY
Background: Death related to unintended pregnancy associated events is a series public health concern in Ethiopia. This is very common in young adolescents for whom life is full of adventure and temptation with very little knowledge about the consequences of their reckless activities. Emergency contraceptives are the only method that can be used within short time after sexual intercourse, offering...
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