Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
SYNTHESIS AND EVALUATION OF MESOPOROUS SILICA NANOPARTICLES (MSN) LOADED COX-II INHIBITOR – MELOXICAM FOR TARGETED COLORECTAL CANCER TREATMENT
Polymer functionalised mesoporous silica nanoparticles hold great promise to enhance drug targeting and cell internalisation for cancer cells. Since the presence of abundant folate receptors on cancer cells, folic acid functionalised mesoporous silica nanoparticles (MSN) were used as folate marker and polyethyleneimine was used to improve cell internalisation. Meloxicam was loaded into the pores o...
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PREVENTION OF GASTRIC EROSION IN INDOMETHACIN ADMINISTERED RATS BY SELECTED ANTIOXIDANTS, VITAMINS AND MINERALS
This investigation was aimed to study the effect of few selected antioxidants, Vitamins and minerals for prevention of gastric erosion in indomethacin induced gastric mucosal damage in rats. Male Wistar rats, weighing between 200 -250 g were divided into 9 groups of 6 animals each (n = 6). The groups were treated respectively as follows Group I normal control and Group II disease control received ...
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ANTI – AGEING ACTIVITY OF MOONG BEAN SPROUTS
The present work was undertaken to justify that Vigna radiate (green moong bean) is helpful in reversing signs of memory loss in aged mice. Passive Avoidance Paradigm (PAP) and Elevated Plus Maze (EPM) were employed as exteroceptive behavioural models and ageing- induced amnesia served as interoceptive behavioural model. Moong bean sprouts (2% and 4% w/w MBS) were administered to mice along with ...
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GLYCOPROTIEN 11b/ 111a RECEPTOR INHIBITOR (TIROFIBAN) FOR FAILED THROMBOLYSIS IN ACUTE ST ELEVATION MYOCARDIAL INFARCTION
We studied the feasibility, safety, clinical benefit, efficacy and 30 day outcome in 50 patients receiving tirofiban in patients with failed thrombolysis in acute ST elevation myocardial infarction, and compared with 50 patients for age, gender and infarct location, who did not receive rescue treatment for different reasons. Tirofiban resulted in an overall ST segment elevation, resolution, at 240...
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IN VITRO ANTILEISHMANIAL ACTIVITY AND GC-MS ANALYSIS OF ETHYLACETATE FRACTION OF ALLIUM CEPA (EAFAC)
In this study, GC-MS analysis shown that ethyl acetate fraction of Allium cepa (EAFAC) (band one) consists of 55 compounds which shown antileishmanial activity. (IC50 73.1 ± 2.1 ug/ml) is the inhibitory concentration which is observed for ethyl acetate fraction of Allium cepa (EAFAC) (band one). Leishmania major is the specie used for this leishmanicidal assay. In this bioassay, Amphotericin B (I...
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DEVELOPMENT OF A NEW ADDITIONAL METHOD TO DISTINGUISH THE INVALID DRUGS AND DETECT DRUG VALIDITY
The threats and risks of the invalid drugs as expired, counterfeit (cheated drugs), Substandard, spurious, falsely labeled, falsified) .The risks and threats of the invalid drugs are many and wide vary, and the countries are trying to prevent these threats by some efforts as the regulatory institution's efforts and the recorded expire date on the drug container, but that are not enough to prevent ...
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DEVELOPMENT OF MEDICAL SAFETY DATA REPORTING PROGRAMS AND HEALTH EDUCATION CENTERS
The reporting of medical safety data (especially medical data related to drug effectiveness and patient safety) and the supplying of the health education and general medical culture are very important issues in any society. And as we all live in one world, so, we should deal with these issues as international issues not only as local issues, and there are reasons and problems make that only a few ...
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ASSESSMENT OF HEART HEALTHY PRACTICES AND CLINICAL RISK FOR COMPLICATIONS AMONG PATIENTS WITH HYPERTENSION AT SELECTED HOSPITAL IN CHENNAI
Background: Hypertension (HTN) is an important public health problem in both economically developed and developing nations. World Health Organization (WHO) data indicate that by 2025 the global burden of hypertension will increase by 60% to be 1.56 billion individuals worldwide and higher in the developed nations. Hence the present study is aimed to assess the heart healthy practices among patient...
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ENZYMES AS TARGETS FOR CANCER THERAPY
Cancer is a deliberating disease affecting people worldwide. Treatment of cancer has become a number one priority among medical specialists and different modes of treatment are being pursued. Various factors are involved in the proliferation of cancer thereby complicating its treatment. Certain enzymes or protein products within the cell can be up-regulated or down-regulated as the cancer progress...
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A REVIEW ON LAGERSTROEMIA SPECIOSA
Lagerstroemia speciosa is commonly known as crape myrtle belonging to the Lythraceae family. Lagerstroemia speciosa or Banaba is a medicinal tree traditionally used to lower blood sugar in the body. Its high content of corosolic acid makes it an effective anti-diabetic drug. Banaba is also recommended for kidney, bladder problems and hypertension. Leaves of the species have been traditionally used...
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