Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
DESIGN AND SYNTHESIS OF BI-METALLIC PORPHYRIN ARRAY
Porphyrins are ever-present large class of naturally occurring macrocyclic compounds with many significant biological representatives comprising heme and chlorophyll. Novel bi-metallic porphyrins derived from [5-(4-hydroxyphenyl)-10,15,20-tri(4-methyl phenyl) porphyrin] and salicylideneamino-2-(N,N-dimethylamino) ethane copper (II) perchlorate was obtained in good yields. The results from various ...
3464
1561
SPECTRAL STUDIES OF NEW ORGANOMETALLIC SCHIFF BASE COMPLEXES AND THEIR ANTI-FUNGAL ACTIVITY
Synthesis of new organometallic Schiff bases complexes with general formula [ML)xH2O] [where M = Mn(II), Ni(II), Cu(II) Pd(II) and Pt(II), L=2,2'-{(1R,1'S)-1,1'Ferrocen-2,4-dien-1-yl-2,2'-diyl bis [(Z)methyl-ylidenenitrilo]}bis(3-iodophenol)] have been prepared and characterized by elemental analysis, magnetic susceptibility, Conductivity IR, UV-Visible, Mass spectra and TGA/DTA. Organometallic Sc...
3889
1687
DESIGNING NATURAL AGONISTS FOR THYROID HORMONE RECEPTOR ALFA-1
Hypothyroidism is a common disorder of endocrine system in which the thyroid gland does not produce enough thyroid hormone. The most common cause of hypothyroidism is inflammation of the thyroid gland, which damages the gland’s cells. It can affect growth, cellular processes and many other body functions. As more damage accumulates, the risk of Hypothyroidism increases. In order to make an impac...
3725
1582
STUDIES ON THE SYNTHESIS AND IN-VITRO ANTIMICROBIAL ACTIVITY EVALUATION OF SOME NOVEL β-LACTAMS CONTAINING SULFA DRUGS
The present study aims to synthesize 2-azetidinone derivatives; 4-(3-chloro-1-(4-substituted-phenyl)-4-oxoazetidin-2-yl)-2-methoxyphenyl-acetate (c1-c6) and 2-allyl-4-(3-chloro-1-(4-Substituted-phenyl)-4-oxoazetidin-2-yl)-6-methoxyphenyl4-methylbenzenesulfonate (d1-d6) by electrocyclisation of imines with chloroacetylchloride in the presence of triethyle - amine and 1, 4-dioxane. The synthesized c...
7755
1522
IDENTIFICATION OF HUMAN cAMP DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT INHIBITORS
Cyclic adenosine monophosphate (cAMP) dependent protein kinase plays a major role in cell signaling pathway. Over expression of extracellular cAMP dependent protein kinase catalytic subunit caused tumorgenesis in prostate. This protein may provide a base for the design of clinically applicable therapeutic strategies. In order to develop potential inhibitor of cAMP dependent protein kinase catalyti...
3358
1476
STUDIES ON THE DEVELOPMENT AND EVALUATION OF COLON SPECIFIC DRUG DELIVERY SYSTEM CONTAINING MEBEVERINE
The main aim of this study was to develop Mebeverine colon specific drug delivery system with increased stability of drug in stomach and small intestine. This stability of drug was achieved by coating of the drug core with Chitosan and Ethyl cellulose polymers by direct compression using tablet punching machine. Mebeverine was a drug whose therapeutic role is in the treatment of Irritable Bowel Sy...
4389
1733
SYNTHESIS, SPECTRAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF COPPER(II), COBALT(II) AND ZINC(II) COMPLEXES OF 6-METHOXY-3-FORMYLCHROMONE
A new series of Cu(II), Zn(II) and Co(II) complexes have been synthesized from 6-Methoxy-3-phenyliminomethyl-chromen-4-one, a Schiff base derived from 6-Methoxy-4-oxo-4H-chromene-3-carbaldehyde and aniline. The nature of bonding and the structure of the complexes have been deduced from IR, UV, 1H NMR spectroscopy. The biological activity of the ligand and metal complexes have been examined against...
3766
3018
ENVIRONMENTAL FRIENDLY WETCHEMICAL SYNTHESIS AND CHARACTERIZATION OF TRANSITION METAL DOPED PARTICLE
Transition metal doped zinc oxide particles were synthesized in aqueous phase adopting a low cost, easy and environmental friendly route. The precursors used in the preparation of Co doped ZnO (Zn0.95Co0.05O) and ZnO (Zn0.9oCo0.1O) by wet process are zinc acetate dehydrates cobalt chloride, sodium hydroxide, di-ethylene glycol and double distilled water. The doped ZnO particles were characterized ...
10512
1371
METHOD DEVELOPMENT AND VALIDATION FOR THE ESTIMATION OF PLERIXAFOR BY RP-HPLC METHOD IN BULK DRUG AND PHARMACEUTICAL DOSAGE FORM
A simple, precise and accurate RP-HPLC method was developed for the determination of Plerixafor in bulk and pharmaceutical dosage forms. The estimation was carried out on Xterra RP 18 (4.6 x 250mm, 5µm) column using a mixture of Methanol: Water (50:50% v/v) as the mobile phase at a flow rate of 0.8ml/min, the detection was carried out at 215nm. The method was validated for linearity, accuracy, pr...
5193
1859
SELF-REPORTED CHRONIC ILLNESSES AND USE OF PRESCRIPTION MEDICINES (PM) AMONG ELDERLY MALAYS- A COMMUNITY BASED STUDY
This study explored self-reported chronic illnesses and use of prescription medicines (PM) by elderly Malays in the community. The study was a population based cross sectional study conducted among 490 Malay subjects aged ≥ 60 years in the semi-urban and rural areas in Perak, Malaysia. The study was conducted using pre-validated questionnaires after getting informed consent from the study partic...
3766
1397