Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
CANCER NANOTHERAPEUTICS – A REVIEW
Present study explains the cancer nano-therapeutics which is rapidly progressing and are being implemented to solve several limitations of conventional drug delivery systems such as nonspecific biodistribution and targeting, lack of water solubility, poor oral bioavailability. To improve the bio-distribution of cancer drugs, nanoparticles have been designed with optimal size and surface characteri...
5472
1824
PERMEATION ENHANCERS COMPATIBLE WITH TRANSDERMAL DRUG DELIVERY SYSTEMS OVERCOMING THE SKIN BARRIER FUNCTIONS: CURRENT AND FUTURE PROSPECTS
Transdermal drug delivery system (TDDS) provides a leading edge over injectables and oral routes by increasing patient compliance and avoiding the first-pass metabolism respectively. Transdermal delivery not only provides controlled, constant administration of the drug, but also allows continuous input of drugs with short biological half-lives and eliminates pulsed entry into the systemic circulat...
3919
1702
“AGATHIYAR KUZHAMBU”- NOT ONLY A PURGATIVE- AN OVERVIEW
The Siddha System of Medicine is one of the most ancient traditional medical systems was popular in the ancient Southern part of India. In this system, the herbals, metals, minerals and animal products have been used to prepare the medicines for treating diverse illness. Siddha medicines are divided into inner drug treatments and external drug treatments. Agathiyar Kuzhambu is one among the 32 int...
11453
2554
INFLUENCE OF THE SUPERDISINTEGRANTS IN NIFEDIPINE RELEASE FROM OSMOTIC PUSH-PULL TABLETS
Push-pull osmotic pumps are controlled drug delivery systems for drugs with a broad range of solubilities; especially drugs that are poorly water-soluble. The aim of the present study was to evaluate the performance of the superdisintegrants (SD), crospovidone (CPVP), croscarmellose sodium (CS), and sodium starch glycolate (SSG), in push-pull tablets containing Nifedipine (NP) as a model drug. We ...
4913
2161
EFFECT OF CO-PROCESS EXCIPIENTS IN FORMULATION OF ODTs USING A MODEL DRUG
Different types of excipients were compared, in terms of their effect in (oral disintegrated tablets-ODTs) to optimize drug delivery and manufacturability. Therefore, the influence of excipients on the quality of ODTs was investigated by formulating and evaluate ODTs using an equal dose of water-soluble Baclofen (B) and poorly water-soluble Meloxicam (M) as model drugs. ODTs of both drugs were pre...
4807
2394
DOSE DEPENDENT ANTIDIABETIC ACTIVITY OF HYDRO-METHANOLIC EXTRACT (3:2) OF FLOWER OF M. BALBISIANA IN STREPTOZOTOCIN INDUCED DIABETIC MALE RAT
Background: Musa balbisiana Colla (Musaceae family) is used as folkloric medicine throughout India. Objective: To search out the potent dose of a hydro-methanolic extract of Musa balbisiana flower for antidiabetic and antioxidative activities in streptozotocin-induced diabetic rat. Material and Methods: The extract of the said plant part was administered orally at the dose of 5, 10 or 20 mg /100 g...
3782
1631
A STUDY OF POSSIBLE PROTECTION BY NEFIRACETAM ON ESLICARBAZEPINE INDUCED MEMORY IMPAIRMENT IN TEMPORAL LOBE EPILEPSY
Memory impairment (MI) is commonly seen in epilepsy and is at times aggravated by antiepileptic therapy. Recent studies reported that co-administration of nootropic agent with an antiepileptic drug (AED) might decrease the MI. This study was designed to evaluate MI activity of Eslicarbazepine (ESL) in temporal lobe epilepsy (TLE) and to assess the protective effect of Nefiracetam (NEF) which is a ...
2972
1200
RECONSTITUTION OF ORAL ANTIMALARIAL SUSPENSIONS: AN UNRECOGNIZED FACTOR IN ANTIMALARIAL DRUG RESISTANCE
Malaria is a foremost universal public health problem, especially in the African region and development of resistance to the older and new generation malaria therapy, has become a persistent health threat requiring urgent solutions. This study intended to assess the ability of human subjects to accurately reconstitute antimalarial dry suspensions according to the manufacturer’s instructions. Two...
4152
1776
IN-VITRO NEUROPROTECTIVE ACTIVITY OF SILIBININ AGAINST MPTP (1-METHYL-4-PHENYL-1, 2, 3, 6-TETRAHYDROPYRIDINE) INDUCED NEUROTOXICITY MODEL
In the present study, we examined the effect of Silibinin on the accumulation of oxidative stress induced by MPTP by in-vitro. After decapitation, healthy rat brain was removed rapidly from the skull and rinsed with cold artificial cerebrospinal fluid (ACSF) which has been equilibrated with 95% O2 / 5% CO2 gas mixture. Group I brain was incubated in CSF serve as normal, Group II lenses brain was i...
2601
1250
ACUTE ORAL TOXICITY AND NEUROBEHAVIOURAL TOXICOLOGICAL EFFECTS OF METHANOLIC EXTRACT OF CHRYSOPHYLLUM PERPULCHRUM IN RATS
This study aimed to investigate the acute toxicity of methanolic extract of Chrysophyllum perpulchrum on biochemical, behavioral and histopathological variation in male Wistar rats. Acute toxicity of the methanol extract of Chrysophyllum perpulchrum was carried out on 36 male rats using different doses of the extract ranging from 500 to 2000 mg/kg body weight. Behavioral tests were used to determi...
2691
1376