Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.87 | 4.57 | 2.15 | 1.07 | 0.58 | 0.38 |
DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR THE ESTIMATION OF DOXOFYLLINE AND TERBUTALINE IN PURE AND IN ITS FORMULATION
A new simple, rapid, and sensitive reversed-phase liquid chromatographic method was developed for the estimation of doxofylline and terbutaline in the tablet dosage form. The chromatographic separation was achieved on ODS C18column (150 × 4.6 mm, 5 µm) at ambient temperature and effluent monitored at 257 nm. The mobile phase consists of ammonium acetate buffer (pH adjusted to 3 with o-phosphoric...
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FORMULATION AND EVALUATION OF SPHERICAL CRYSTALS OF INDOMETHACIN FOR THE IMPROVEMENT OF SOLUBILITY AND MICROMERITIC PROPERTIES
Indomethacin, an anti-inflammatory drug, exhibits poor water solubility and flow properties. Spherical agglomerates were prepared by crystallo-co agglomeration technique. Crystallization medium used for spherical agglomerates of Indomethacin consisted of acetone (good solvent); water (poor solvent); dichloromethane (bridging liquid). HPMC, PVP and PEG6000 this polymer were used in the agglomeratio...
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IN-VITRO EVALUATION OF EFFECT OF HYDROALCOHOLIC MEDIA ON DRUG RELEASE FROM SUSTAINED RELEASE FORMULATION
In the recent development, worldwide consumption of alcohol has shot up in the past decade as a part of lavish and Gen next lifestyle changes. There have been innumerable instances of people consuming alcoholic beverages and drugs at the same time. Hence in our study, Diclofenac and Metformin were selected as representatives of highly prescribed and overused drugs. Hence, the present study was pla...
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IMPACT OF CELL SENESCENCE ON AGE – RELATED NEURODEGENERATIVE DISORDERS: THE MECHANISM TO THERAPY- A REVIEW
Aging is a natural phenomenon; it is a well-known fact that everyone is aging as time passes. A major contributor to this process is cell senescence. Cell senescence can be a result of the exposure to stress such as oxidative stress, epigenomic damage or DNA damage, or it can be due to telomere shortening is also known as end replication problem. It was first observed by Hayflick. Senescent cells ...
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1872
RECENT ADVANCES IN THE SYNTHESIS OF PHARMACOLOGICALLY BENIGN COUMARIN AND INDOLE HETERO-STRUCTURED DERIVATIVES: A REVIEW
Indole and coumarin are the most versatile and cogent heterocyclic scaffolds which are not only decisively used in the synthesis of various organic compounds but also play a consequence role in natural product synthesis, modulation of biofilm formation, virulence and stress responses. In last few decades, an individual has witnessed considerable activity towards the synthesis of indole derivatives...
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CANCER NANOTHERAPEUTICS – A REVIEW
Present study explains the cancer nano-therapeutics which is rapidly progressing and are being implemented to solve several limitations of conventional drug delivery systems such as nonspecific biodistribution and targeting, lack of water solubility, poor oral bioavailability. To improve the bio-distribution of cancer drugs, nanoparticles have been designed with optimal size and surface characteri...
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1859
PERMEATION ENHANCERS COMPATIBLE WITH TRANSDERMAL DRUG DELIVERY SYSTEMS OVERCOMING THE SKIN BARRIER FUNCTIONS: CURRENT AND FUTURE PROSPECTS
Transdermal drug delivery system (TDDS) provides a leading edge over injectables and oral routes by increasing patient compliance and avoiding the first-pass metabolism respectively. Transdermal delivery not only provides controlled, constant administration of the drug, but also allows continuous input of drugs with short biological half-lives and eliminates pulsed entry into the systemic circulat...
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“AGATHIYAR KUZHAMBU”- NOT ONLY A PURGATIVE- AN OVERVIEW
The Siddha System of Medicine is one of the most ancient traditional medical systems was popular in the ancient Southern part of India. In this system, the herbals, metals, minerals and animal products have been used to prepare the medicines for treating diverse illness. Siddha medicines are divided into inner drug treatments and external drug treatments. Agathiyar Kuzhambu is one among the 32 int...
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INFLUENCE OF THE SUPERDISINTEGRANTS IN NIFEDIPINE RELEASE FROM OSMOTIC PUSH-PULL TABLETS
Push-pull osmotic pumps are controlled drug delivery systems for drugs with a broad range of solubilities; especially drugs that are poorly water-soluble. The aim of the present study was to evaluate the performance of the superdisintegrants (SD), crospovidone (CPVP), croscarmellose sodium (CS), and sodium starch glycolate (SSG), in push-pull tablets containing Nifedipine (NP) as a model drug. We ...
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EFFECT OF CO-PROCESS EXCIPIENTS IN FORMULATION OF ODTs USING A MODEL DRUG
Different types of excipients were compared, in terms of their effect in (oral disintegrated tablets-ODTs) to optimize drug delivery and manufacturability. Therefore, the influence of excipients on the quality of ODTs was investigated by formulating and evaluate ODTs using an equal dose of water-soluble Baclofen (B) and poorly water-soluble Meloxicam (M) as model drugs. ODTs of both drugs were pre...
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