Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
FORMULATION AND CHARACTERIZATION OF SOLID DISPERSIONS OF A POORLY SOLUBLE FENOFIBRATE
Solid dispersion is one of these methods, which was most widely and successfully applied to improve the solubility, dissolution rates and consequently the bioavailability of poorly soluble drugs. The solid dispersions based on the concept that the drug is dispersed in an inert water-soluble carrier at solid state. Several water soluble carriers such as methyl cellulose, urea, lactose, citric...
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ANTIMICROBIAL POTENTIAL OF SOME INDIAN MEDICINAL PLANTS AGAINST DRUG-RESISTANT PATHOGENS
Many infectious diseases are known to be treated with herbal remedies throughout the history of mankind. Even today, plant materials continue to play a major role in primary health care as therapeutic remedies in many developing countries. Traditional system of medicine is found to have utilities as many accounts. Due to population rise adequate supply of drug and high cost of treatment in side ef...
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INDIA – A NEW CONTRIBUTOR TO THE PHARMACOVIGILANCE MOVEMENT
Every drug has two facets and the sinister side is becoming more apparent every day, sometimes resulting in product recalls by regulatory agencies due to serious adverse effects. Monitoring of unwanted side effects of allopathic drugs administered alone, and in combination with other drugs or dietary products causing drug-drug and drug-herbal/food interactions were lacking earlier, but information...
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FREQUENCY OF MILD AND SEVERE DEPRESSION CONSIDERING THE GENDER AND BLOOD GROUPS AMONG MEDICAL STUDENTS OF INTERNATIONAL MEDICAL AND TECHNOLOGICAL UNIVERSITY (IMTU), DAR ES SALAAM
Objective: Study to elucidate the relation between depression, gender and blood groups. Methods: The study was prepared on 279 medical students of IMTU, who have spent more than four months in the medical school. A Performa for testing depression scale was given to the students. Blood groups and gender were analyzed. Results: It was evident that few blood groups like A and O shown significan...
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SYNTHESIS, CHARACTERIZATION AND ANALGESIC ACTIVITY OF SEVERAL NEW N-SUBSTITUTED PHTHALIMIDE ANALOGUES
The synthesis, characterization and spectroscopic studies of new N-substituted pthalimide analogues 2–7 with analgesic activity were described. The compounds were synthesized using phthalic anhydride with various appropriate amines (Triazolamine, Benzocaine, p-Nitro-aniline, pyrazinamide, Phenazone and glycine) in reflux synthesizer. The purity of the compounds was determined by TLC. With the ph...
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TRANSGENIC LYCOPERSICUM ESCULENTUM MILL (TOMATO) PLANT AS BIOREACTOR FOR THE PRODUCTION OF HUMAN NEUTROPHIL PEPTIDE-1 (HNP-1): A USEFUL PROTEIN BASED PHARMACEUTICAL
The term ‘transgenic plant’ is defined as the plants that are produced in the lab by artificial insertion of genes sometimes from the same species and sometimes entirely from the different kingdom. A major advantage of transgenic plant because of which it gains a lot of importance in today’s world is developing it for producing pharmaceutically useful compounds. Hence, they are act...
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MODULATION OF TUMOUR NECROSIS FACTOR Α ATTENUATES NALOXONE-PRECIPITATED OPIOID WITHDRAWAL SYNDROME
The present study has been designed to investigate the effect of modulation of tumour necrosis α (TNF-α) on naloxone induced opioid withdrawal syndrome. Chronic morphine (5mg/kg,i.p) administration followed by a single injection of naloxone (8mg/kg, i.p) was used to precipitate opioid withdrawal syndrome in mice. Behavioral observations were made immediately after naloxone treatment. Withdrawa...
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SEROLOGICAL TESTING IN ASTHMA PATIENTS VISITING MAHAVIR HOSPITAL AND RESEARCH CENTRE
Background: The hypothalamic pituitary adrenal (HPA) axis in asthmatic patients is influenced by many factors. Stress, cytokines and exogenous corticosteroids play an important role in regulating the HPA axis and thus affecting the adreno corticotrophic hormone (ACTH) and cortisol levels among these patients. It is well accepted that the HPA axis represents a major immune-regulatory system that pl...
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NOVEL THERAPEUTIC OPTIONS FOR FAMILIAL HYPERCHOLESTEROLEMIA
Background: Familial Hypercholesterolemia (FH) is an autosomal dominant disorder caused by mutation in the LDL receptor gene and characterized by raised LDL-C, tendon xanthomata and premature atherosclerosis. Existing therapies for FH such as statins and LDL apheresis do not offer adequate lipid control in most patients, which has led to the search for more definite alternatives. Two new drugs hav...
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NEEM LEAF EXTRACT PREVENTS METHOTREXATE INDUCED GENOTOXICITY IN THE SOMATIC CELLS OF DROSOPHILA MELANOGASTER”
Background &Objective: To explore possible protective effect of neem leaf extract against methotrexate induced genotoxicity in the somatic cells (wing primordial) of Drosophila melanogaster. Methods: In the first phase of the experiment, neem leaf extract (NLE) at two doses was tested in the somatic cells (wing primordia) of Drosophila melanogaster (3rd instar trans heterozygous larvae resu...
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