Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
AN UPDATE ON NOVEL TECHNOLOGIES, IN-VITRO AND IN-VIVO MODELS FOR TUBERCULOSIS AND TUBERCULOUS MENINGITIS
Tuberculosis is a bacterial infection which is caused by the bacteria Mycobacterium tuberculosis. It is next to AIDS and causes morbidity and mortality. These bacteria can stay in the host’s body for decades. In this article we have mentioned about the pathogenesis of pulmonary tuberculosis followed by the pathogenesis of tuberculous meningitis wherein the bacteria first enter to the lungs which...
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POLYCYSTIC OVARIAN SYNDROME AND ITS METABOLIC CONSEQUENCES: A MINI REVIEW
Polycystic ovarian syndrome (PCOS) is a reproductive metabolic disorder affecting nearly 20% females, globally. Though Rotterdam consensus is widely used for assessment, it lacks definite diagnostic guidelines. Absence of PCOS guidelines for adolescent and post-menopausal women might be influencing the prevalence data. The prevalence varied with ethnicities and found high in urban than rural. Amon...
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NFκβ INHIBITION MECHANISM OF DEOXYELEPHANTOPIN AND ISODEOXYELE-PHANTOPIN WITH QSAR AND MOLECULAR DOCKING
Deoxyelephantopin and isodeoxyelephantopin are member of a group of compounds, sesquiterpene lactones, that include proven anticancer agents against many types of cancer cells. Many sesquiterpene lactones suppress cancers by inhibiting NFκβ. This study explores the inhibitory interaction between deoxyelephantopin and isodeoxyelephantopin on NFκB using QSAR and molecular docking. Physicochemical...
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TO EVALUATE THE USE AND SAFETY OF BLOOD THINNING AGENTS IN TERTIARY CARE HOSPITAL
Objective: To ensure the basic principles of drug utilization and the use and safety of blood thinning agents in tertiary care hospital. Experimental design: The study included 224 patients’ and was conducted in a tertiary care hospital and we were focused on to find out the drug-drug interactions of anticoagulants, antiplatelet, and thrombolytic agents, to study the major area involvement for b...
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THE HEPATIC CYP3A4 UPREGULATED INCREASED METABOLISM IN RESPONSE TO PHYSICAL ACTIVITY AT HIGH ALTITUDE
The present study was designed to assess the pharmacokinetics of drug metabolized by hepatic cytochrome 3A4 (CYP3A4) in human volunteers with physical activity at the high altitude hypobaric hypoxic environment. The International Physical Activity Questionnaire short form 7 (IPAQ SF-7) was used to measure the physical activity. The total of 24 healthy male volunteers participated in this study; fo...
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CRISPR-Cas9 MEDIATED GENOME EDITING IN ESCHERICHIA COLI
Clustered regularly interspaced palindromic repeats are the centerpiece of a robust adaptive bacterial immune system that forms the basis for the CRISPR-Cas9 genetic engineering technology. CRISPR-associated protein-9 (Cas9) is part of this immune system that seeks out, cuts, and degrades viral DNA. By taking advantage of the CRISPR-Cas9 system, a tool has been developed to delete or insert DNA in...
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AN IN-VITRO PHAGE THERAPY – IN OPPOSITION TO FOOD POISON ENGENDERED STAPHYLOCOCCUS AUREUS VIA PRECISE BACTERIOPHAGE FROM TIRUNELVELI DISTRICT, TAMIL NADU
Staphylococcus aureus, the facultative anaerobic and opportunistic Bacterium has been characterized as the pathogen with diversified molecular adaptability leading to the emergence of MDR. Advanced use of alternate antibiotics is increasing the scenario of the emergence of Methicillin-Resistant Staphylococcus aureus (MRSA) to Oxacillin Resistant Staphylococcus aureus (ORSA) after that generating a...
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THE EFFECT OF MEDIA AND FERMENTATION CONDITION TOWARD ANTIBACTERIAL ACTIVITIES OF BACILLUS SP. DA11 ASSOCIATED WITH SARCOPHYTON SP.
The emergence of antibiotic-multidrug resistant microorganisms is an essential issue in the health sector. Consequently, the exploration of new antimicrobial compounds from many promising resources is urgently required. Soft coral-associated bacteria are potential as antimicrobial compound producers. This study aims to get the best medium and fermentation conditions in the production of secondary ...
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COMPOUNDS FROM TROPIDIA CURCULIOIDES AS INDUCERS OF APOPTOSIS IN CANCER CELLS
Arunachal Pradesh (AP), the North-eastern state of India, is a natural habitat of 550 species of orchids including 37 species of medicinal importance. Though these plants are used extensively by locals for various ailments, very few scientific investigations have been conducted to establish their pharmacological potential. In the present study, we selected Tropidia curculioides, a relatively unexp...
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SURVEILLANCE AND ASSESSMENT OF ADVERSE DRUG REACTIONS AND COMPARISON WITH THE RETROSPECTIVE STUDIES IN A SECONDARY CARE HOSPITAL
Adverse drug reactions are considered to be among the leading causes of morbidity and mortality. Approximately 5-25% of hospital admissions are due to ADR’s, and 6-15% of hospitalized patients experience serious adverse drug reactions (SADR’s), causing significant prolongation of hospital stay. The adverse drug reactions reported were classified based on Wills and Brown classification, Causali...
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