Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
CHARACTERIZATION AND QUANTIFICATION OF ETHYLHEXYLGLYCERIN
Ethylhexylglycerin is an alkyl glyceryl ether. This means that the ethyl hexyl group is bound to glycerin at one end by an ether linkage. it has been used as a common ingredient in bath products, body and hand products, cleansing products, deodorants, eye makeup, foundations, hair care products and suntan products. The compound is synthesized by esterfication of 2-Ethylhexanol and epichlorohydrin,...
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A JOURNEY OF DIETARY NITRATE AS A HEALTH PROMOTER
Dietary nitrate has been demonstrated to have a range of beneficial vascular effects, including reducing blood pressure, reduction in pulse wave velocity, regulation of cerebral blood flow, enhancing exercise performance in healthy individuals, stimulating angiogenesis and vasculogenesis etc. Earlier studies with nitrate or nitrite also demonstrate the synergistic effects against ischaemia-reperfu...
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MOLECULAR MODELLING AND MOLECULAR DOCKING STUDIES OF CYP450 INHIBITORS
The present study explains computational methods to design 3D structure of “Cytochrome P450 4A11” of Homo sapiens enzyme using the sequence available from Uniprot (Uniprot KB - Q02928). Homology modelling study was performed to generate a 3D model of Cytochrome P450 protein. The model was developed by using Modeler 9.17 software tool. The developed model was further docked with already existin...
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3D QSAR AND MOLECULAR DOCKING STUDIES OF FLAVONOIDS AS SPLEEN TYROSINE KINASE INHIBITORS
Spleen tyrosine kinase (Syk) is a member of tyrosine kinase family protein. Syk protein plays a vital role during intracellular signal transduction from high affinity IgE receptor (FcεRI) in allergic reaction. Flavonoids are well known compounds for their anti-allergic properties. In this present work, thirty-four structurally similar flavonoids are investigated as Syk inhibitors by using 3-dimen...
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SYNTHESIS, EVALUATION AND POLYMORPHISM STUDIES OF NEW BENZIMIDAZOLE DERIVATIVES AS POTENT ANTIBACTERIAL AGENTS
Ten, 2-substituted benzimidazole derivatives were prepared and assessed against two Gram-positive bacteria (Streptococcus mutans, Staphylococcus aureus) and two Gram-negative bacteria (Psuedomonas aeruginosa, Escherichia coli). The derivatives were obtained by the condensation of 2-((1H-benzo[d] imidazol-2-yl) thio) acetohydrazide(4) with different substituted aromatic aldehydes and their structur...
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EVALUATION OF RENAL EFFECTS OF HYDRO-ALCOHOLIC EXTRACT OF PORTULACA OLERACEA (WHOLE PLANT) IN ALLOXAN INDUCED DIABETIC RATS
Herbal plants are effective in the treatment of various diseases. More or less they are unscientifically and improperly used. These plants deserve detailed studies in the light of modern medicine. Having detailed investigation and documentation of herbal plants used in local health traditions and after that doing pharmacological evaluation of these plants and...
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HYDROCOTYLE SIBTHORPIODES EXTRACT LOADED IN CHITOSAN NANOCAPSULE AS AN EFFECTIVE ANTIBACTERIAL AGENT AGAINST FEW PREVALENT MICROBES IN WOUND
Hydrocotyle sibthorpiodes is a known medicinal plant and is used for treatment against many bacterial and fungal pathogens in a conventional application form. The present study was intended to enhance the activity of H. sibthorpiodes plant extract against four bacterial species in combination with clove oil and silver nanoparticles by preparing a chitosan based nanocapsule that cause chronicity in...
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CHARACTERIZATION AND STABILITY OF EXTRACELLULAR ALKALINE PROTEASES FROM HALOPHILIC AND ALKALIPHILIC BACTERIA ISOLATED FROM SALINE HABITAT OF LONAR SODA LAKE, INDIA
Culture dependent phenotypic characterization analyses were applied to study the protease producing bacteria from Indian Soda (Lonar crater). The uniqueness of the Lonar lake water is its salinity and alkalinity. A total of one hundred and fourteen bacterial cultures were isolated from the water and sediment samples collected from the hyper alkaline saline environment of Lonar lake. The thirty two...
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PROGNOSTIC UTILITY OF LILLE SCORE IN ALCOHOLIC HEPATITIS
Background: Alcoholic liver disease is a spectrum of alcohol induced injury that includes fatty liver, alcoholic hepatitis and alcoholic cirrhosis. Corticosteroids are used in cases of severe alcoholic hepatitis with Maddrey’s Discriminant Function score > 32. However, many of the patients who are being managed by corticosteroids are non responders and mortality increases in such patients. Li...
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MOLECULAR DOCKING STUDIES OF THE COMPOUNDS FROM PERGULARIA DAEMIA AND TERMINALIA CATAPPA L. LEAF EXTRACTS WITH CYP2E1,GST,UDP-GLUCURONYL TRANSFERASE AND Nrf2 BINDING SITE IN KEAP1, IL-6
Objective: Pergularia daemia and Terminalia catappa L.. Leaf extracted with hydroethanol and the extracts were separated by silica gel column chromatography. The selected column fractions are used in GC-MS analysis, from the GC-MS results eight phytochemical compounds are selected based on their biological activities. In the present work we predict the interaction of the selected targeted protei...
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