Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
IN-VITRO MUTAGENIC, GENOTOXIC AND ANEUGENIC POTENTIAL OF OMEPRAZOLE
The aim of this investigation was to re-evaluate the in-vitro mutagenic, genotoxic, and aneugenic potential of omeprazole through the Ames test, comet (SCGE), and cytokinesis-block micronucleus assays (CBMN), as previous reports on the mutagenic and genotoxic effects of omeprazole are scarce and inconclusive. The results of this study indicated a negative mutagenic effect through the Ames test. Co...
2948
1428
GENOMIC STRUCTURAL IDENTIFICATION AND IMMUNOINFORMATICS STUDIES FOR SARS‐COV‐2
Coronaviruses are a group of viruses that belongs to the Coronaviridae family. These viruses have helical symmetry, enveloped, positive-sense, single-stranded RNA genome with nucleocapsid that causes diseases in birds and mammals. SARS-CoV 2 complete genome has genome size of 29,903 bp, having nine genes identified as Orf1a Polyprotein, Orf1ab Polyprotein, ORF3a Protein, ORF7a Protein, ORF8 Protei...
4144
998
SYNTHESIS AND CHARACTERIZATION OF 6 – HYDROXY – 3, 4 -DIHYDROQUINOLINONE CILOSTAZOL IMPURITY-A AS PER INDIAN PHARMACOPOEIA
Impurity profile study is critical for getting market approval of finished dosage forms from regulatory authorities. There are many manufacturing firms (small and medium scale) in India that they cannot afford the high priced USP reference standards for analysis. So, the availability of cheaper affordable IP reference standards will help them adhere to quality guidelines for active pharmaceutical ...
2927
2533
FORMULATION AND CHARACTERIZATION OF CLOZAPINE ADHESIVE PATCHES USING VARIOUS PRESSURE SENSITIVE ADHESIVES AND PERMEATION ENHANCERS
The present research work was intended to develop and characterize the transdermal adhesive patch of clozapine using different types of acrylate, polyisobutylene and silicon adhesives. Various permeation enhancers such as 1, 8 – cineole, D-limonene, Azone, IPM and Oleic acid were also evaluated to achieve desired permeation rate and hence to attain the improved bioavailability as compared to ora...
1956
1202
ANALYSIS OF BIOLOGICALLY ACTIVE COMPOUNDS IN JIMSON WEED LEAFS
Jimson weed (Datura stramonium) members of the Solanaceae plant family; serve as major folklore medicinal herbs. The biologically active compounds spectrum in leaves of Datura stramonium L. was investigated by GC-MS with NMR & FTIR analysis. Steroids, terpenoids, anticholinergic alkaloids, atropine, and scopolamine, are detected. Twenty of them are new constitutions for the species, and eight ...
2308
1294
DEVELOPMENT, OPTIMIZATION AND IN-VITRO CHARACTERIZATION OF GLICLAZIDE NANOSPONGE TABLETS FOR ORAL ADMINISTRATION
Poor bioavailability by the oral route is noticeable with the majority of new active pharmaceutical ingredients due to its dissolution rate-limited absorption. Gliclazide is an oral anti-hyperglycemic drug, though it is a class II drug, results in poor oral bioavailability. The present investigation was undertaken to prepare polymeric nanosponges of an oral anti-hyperglycemic drug Gliclazide to ac...
2190
1458
STRUCTURE BASED VIRTUAL SCREENING IN SEARCH OF POTENTIAL INHIBITORS AGAINST HGPRT AS TARGET FOR PLASMODIUM FALCIPARUM
Malaria is a parasitic infectious disease transmitted through the bite of female Anopheles mosquitos. Every year, approximately 210 million Peoples are suffering from this dangerous disease, and around 440,000 individuals pass from this infectious disease. Recently, the Indonesia Ministry of Health declared that the malaria pre-elimination stage should be reached by 2020 and be free of malaria tra...
1952
1126
EFFECT OF INCENSE SMOKE ON THE BEAS-2B AND EB-3 CELLS
Usage of incense smoke has aesthetic importance. But, studies have shown that incense smoke has oxides of carbon, nitrogen, sulphur, which has ill effects on human health. Polyphenol analysis showed the presence of phenol-like compounds in the water extracts of the incense. This study was conducted to understand the impact of exposure of cells to these types of smokes by performing viability test ...
2352
1091
IMPROVED BIOAVAILABILITY OF LINAGLIPTIN BY RESVERATROL IN RATS- INVOLVEMENT OF PERMEABILITY GLYCOPROTEIN (P-gp) INHIBITION
The maintenance of an appropriate serum concentration of a drug is important to ensure therapeutic efficacy. Functional alterations of drug transporters may influence the serum concentration of drugs through changes in its pharmacokinetics and pharmacodynamics (PK/PD). In this study, we have focused on the influence of functional alterations in the intestinal P-glycoprotein (P-gp) on the PK of lin...
2028
1249
SYNTHESIS AND 2D-QSAR STUDY OF SOME NOVEL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES AS ANTITUBERCULAR AGENTS
In the present work, a series of some novel substituted benzimidazole derivatives were efficiently synthesized, and a thin layer chromatography study confirmed the completion of the reaction on silica gel-G plates. The characterization was done through recording spectra of FTIR using Jasco FTIR-460 plus spectrophotometer, recording spectra of 1HNMR with the help of spectrometer, specifically BRUKE...
2121
1064