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ISSN (Online): 0975-8232,
ISSN (Print): 2320-5148

International Journal Of
Pharmaceutical Sciences And Research

An International Journal published monthly
An Official Publication of Society of Pharmaceutical Sciences and Research

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Most Cited

CITATIONS REPORT: (Source- Google Scholar)
 
Year 202020212022Total
No. of Published Articles 745760548 2053
Citations 69926321 983
Projected Impact Factor 5.22.730.64  
Total Citations: 58203
 
Title
Views
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Cited
30.

MAPPING OF NATURAL KAPOSI SARCOMA INHIBITOR USING NETWORK BIOLOGY APPROACH

Identification of protein-ligand interactionnetworks on a proteome scale is crucial to address a wide range of biological problems such as correlating molecular functions to physiological processes and designing safe and efficient therapeutics. In this study we have developed a novel computational strategy to identify ligand binding profiles of proteins across gene families and applied it to predi...

Sadegh Saremy and Jayadeepa R. M.*

Institute of Computational Biology, Bangalore, Karnataka, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(3).853-57

853-857

2927

1170

32.

DEVELOPMENT OF FAMOTIDINE FLOATING DRUG DELIVERY SYSTEM USING NATURAL POLYMERS

In the present study,FDDS of Famotidine, a copmpetative inhibitor of histamine H2 receptors were prepared by using natural gums viz. xanthan gum and guar gum at different drug to gum ratio using sodium bicarbonate and citric acid as gas generating agents and lactose as diluent.FDDS tablets were prepared by wet granulation technique using PVP K30 as granulating agent. The prepared FDDS tablets were...

Mohammed Muqtader*, Farhat Fatima and Sadath Ali

Assistant Professor, Deccan School of Pharmacy, Zafargadh, P.O. Kanchanbagh, Hyderabad-58, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.3(3).863-67

863-867

3989

1278

20.

IONTOPHORESIS OF FLUVASTATIN SODIUM: STUDY OF VARIOUS FACTOR AND IN-VITRO PERMEATION

Fluvastatin sodium (FVS) is the first fully synthetic 3-hydroxy-3-methylglutaryl coenzyme (HMG-CoA) reductase inhibitors used for the treatment of hypercholesterolemia. It shows extensive first pass metabolism with short plasma half-life (3 hrs). The iontophoresis approach was used to determine the permeability of drug through isolated rat skin. In-vitro permeation of drug was determined by using ...

C.J. Tank*, G.K. Kapse , J.I. Sarvaiya

PARTH’’, Vanganga Society, Timbavadi, Ta.Dist. – Junagadh, PIN – 362015, Gujarat, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(9).3444-52

3444-3452

3407

1193

29.

COMPARATIVE STUDY OF OVERLAPPING GENES IN THE GENOMES OF MYCOPLASMA HOMINIS AND MYCOPLASMA PENETRANS

Overlapping genes are pairs of adjacent genes whose coding regions are partially or entirely overlapping. Overlapping genes in prokaryotes are a means to minimize genome size and increase the density of genetic information. Overlapping genes play an important role in genome reduction of Mycoplasmas during the course of their degenerative evolution. In this study overlapping genes in the genomes of...

Kandavelmani Angamuthu* and Shanmughavel Piramanayagam

Research and Development Centre, DBT Bioinformatics Facility, Department of Bioinformatics, Bharathiar University, Coimbatore – 641046, Tamil Nadu, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(9).3504-17

3504-3517

3547

1197

32.

DESIGN OF QUINOLONE DERIVATIVES AS POTENTIAL ANTIBACTERIAL USING MOLECULAR DESCRIPTORS

In the present work in mathematical modeling, quantitative structure activity relationship (QSAR) studies were performed on some quinolone derivatives as a potential antibacterial agent using statistical work. The regression analysis of the data has shown that the activities of the compound can be modeled excellently in bi-parametric model.A heurisimatedtic algorithm selects the best multiple line...

Kumar Nandan

Department of Chemistry, T.N.B. College, T. M. Bhagalpur University, Bhagalpur- 812007, Bihar, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(9).3532-35

3532-3535

2968

1103

39.

FORMULATION AND IN VITRO EVALUATION OF SALBUTAMOL SULPHATE SUSTAINED RELEASE TABLET BY USING FLOATING DRUG DELIVERY TECHNOLOGY

The present study involves in the preparation and evaluation of floating tablets of Salbutamol sulphate by direct compression method by using the hydrophilic polymer such as hydroxy propyl methyl cellulose (HPMC), Sodium carboxy methyl cellulose, Dextrin and Carbopol. Sodium bicarbonate, Tartaric acid and citric acid were incorporated as gas generating agent. The study aims to achieve different fo...

Arup Ratan Deb*, Padmakana Malakar , Nilufa Yeasmin and Siraj Ahmed

Department of Pharmaceutics, Moonray Institute Pharmaceutical Sciences , Mahbubnagar, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(9).3575-81

3575-3581

5707

1516

41.

NEW POTENTIAL ANTIMALARIAL AGENTS: SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME SCHIFF BASE LIGAND AS ANTIMALARIAL AGENTS

Plasmodium falciparum is the protozoan parasite responsible for the majority of life-threatening cases of human malaria, causing more than one million deaths a year. The global emergence of drug-resistant malarial parasites necessitates identification and characterization of novel drug targets. At present, α-carbonic anhydrase (CA) genes are identified in limited numbers of parasites in both prot...

Gopal Garg*, Ashish Acharya and Kuldeep Patel

VNS Institute of Pharmacy, Ratibad road, Bhopal- 462031, Madhya Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(9).3588-95

3588-3595

4091

1260

43.

STRUCTURE MODIFICATION OF RITONAVIR WITH CARBAZOLE; SYNTHESIS AND CHARACTERIZATION

The core moiety of ritonavir (2S, 3S, 5S)-5-(tert-butyloxycarbonyl)amino-2-amino-3-hydroxy-1,6-diphenylhexane (7) on condensation with oxirane of carbazole (8) in isopropyl alcohol at reflux and deprotected with mineral acid gave compound 10. Coupling of compound 10 with carbamate amino acid (11a-15c) in the presence of EDAC.HCl and HOBt at room temperaturegave ritonavir analogues containing carba...

V. Pandu Ranga Rao*, N. Senthil Kumar , Shankar B. Reddy , Aminul Islam and B. Hari Babu

Chemical Research and Development, APL Research Centre-II, Aurobindo Pharma Ltd., Medak District-502329, Andhra Pradesh, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(9).3601-07

3601-3607

3786

1552

46.

SYNTHESIS, CHARACTERISATION AND ANTIFUNGAL STUDIES OF Cu (II) HALIDE COMPLEXES OF SOME STERYL DERIVATIVES OF SUBSTITUTED BENZIMIDAZOLES

Complexes of Copper (II) halides with steryl derivative of 2- methylbenzimidazole (stmbz), 2-ethylbenzimidazole (stebz) and 2-benzylbenzimidazole (stbbz) of composition CuL2X2 (L = stmbz, stebz and stbbz and X = Cl, Br) have been prepared and characterised. The magnetic susceptibility e.p.r. data, electronic absorption pattern and i.r. spectral studies of complexes indicated distorted octahedral e...

L.K. Mishra* and Madhu Bala

Professor, Department of Chemistry (Retd.), Patna University, Patna- 800 005, Bihar, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.4(9).3620-24

3620-3624

3079

1290

1.

HISTAMINE SUBTYPE 3 RECEPTOR ANTAGONISTS: CURRENT STATUS WITH FUTURE PROSPECTS IN DRUG DISCOVERY AND DRUG DEVELOPMENT

The  histamine  H3 receptor is  an  G protein-coupled  receptor that regulates neurotransmission  in  the  central  nervous  system  and plays a major role in cognitive and homeostatic functions. The third histamine receptor was discovered in 1983 by a traditional pharmacological approach, consisting of assessing the inhibitory effect of histamine on its own release from depolarized rat...

Shreya Singh and Satyendra K. Rajput*

Amity Institute of Pharmacy, Amity University, NOIDA, Uttar Pradesh-201303, India

DOI: http://dx.doi.org/10.13040/IJPSR.0975-8232.6(2).502-09

502-509

8380

2396