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IN-SITU OPHTHALMIC GEL FORMING SOLUTION OF MOXIFLOXACIN HYDROCHLORIDE FOR SUSTAINED OCULAR DELIVERY
Human eye is a challenging subject for topical administration of the drugs because of its peculiar anatomical arrangements of surface tissue and impermeability of the cornea. Topical instillation of drugs through eye drops is the most important and well-accepted route of administration for the treatment of various eye disorders. Conventional ophthalmic drug delivery systems often result in poor bi...
8547
2058
VARIATION IN β – SITOSTEROL CONTENT FROM CASSIA FISTULA L. FRUIT PULP COLLECTED FROM DIFFERENT GEOGRAPHICAL REGIONS
Cassia fistula L. (Fabaceae) fruits are reported to possess a wide range of therapeutic properties. In the present work, an HPTLC method has been developed and validated for estimation of β-sitosterol content in C. fistula fruit collected from different geographical regions in and outside India and its polyherbal formulation. Chromatographic separation was achieved on HPTLC plates pre-coated with...
8532
1935
SYNTHESIS AND BIOEVALUATION OF KETOCONAZOLE THIOSEMICARBAZONE ANALOGUES
Ketoconazole (KTZ) is a synthetic antifungal drug used to prevent and treat fungal infections, especially in immunocompromised patients such as those with AIDS. Resistance to ketoconazole has been observed in a number of clinical fungal isolates, including C. albicans. Thus new effective agents with less toxicity against fungal infection are urgently required. With this view, ketoconazole thiosemi...
8532
2020
COSMETICS UTILIZATION PATTERN AND RELATED ADVERSE REACTIONS AMONG FEMALE UNIVERSITY STUDENTS
Background: Cosmetics are articles applied to the human body for cleansing, beautifying, promoting attractiveness or altering appearance. In the last few years, the consumption of cosmetics has touched new heights and the curve is shooting upwards. Along with this, cosmetics are causing alarming adverse reactions to consumers and hence studying their utilization pattern and impact besides beautify...
8523
2119
A PHARMACOLOGICAL AND TOXICOLOGICAL REVIEW OF LAWSONIA INERMIS
Herbal medicines are in great demand in the developed as well as developing countries for primary healthcare because of their wide biological and medicinal activities, higher safety margins and lesser costs. Lawsonia inermis L. is commonly known as Henna or Mhendi and abundantly available in tropical and subtropical areas. Henna belongs to lythraceae, also known as the loosestrife family. Ancient ...
8510
3300
ANTIMICROBIAL ACTIVITY OF UPAVISHA AND ITS CLINICAL CORRELATION WITH CONTEMPORARY SCIENCE: A REVIEW
In Ayurveda, there are less toxic herbal drugs known as upavisha. Upavisha are mostly use in various diseases with many therapeutically preparations. As per Ayurveda, Upavisha is group of less toxic drug. These drugs are either not having all ten gunas or they have less potent gunas. The properties of these drugs are to cure acute and chronic disease. These groups also have antimicrobial/ anti- in...
8499
3417
ISOLATION AND CHARACTERIZATION OF MICROBES PRODUCING BACTERIOCIN FROM CURD, RAW MILK AND SOIL AND ITS PRESERVATIVE EFFECTS
Bacteriocins are proteinaceous substance produced by bacteria to inhibit the growth of similar or closely related bacterial strains. They are typically considered to be narrow spectrum antibiotics produced by both gram negative and gram positive range of bacteria which possess antimicrobial properties and inhibitory towards sensitive strains. Bacterocins are safer than antibiotic. They can be used...
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2797
BENZOTRIAZOLE: A HETEROCYCLIC MOLECULE WITH DIVERSIFIED PHARMACOLOGICAL ACTIVITIES
1,2,3-Benzotriazole (BTA) is a heterocyclic compound with three nitrogen atoms. The enormous investigations on derivatives of benzotriazole reveals wide applicability of this molecules for tagging and delivering huge number of heterocyclic nuclei. This molecule has been used for the analytical determination of silver as well as a restrainer in photographic emulsions. The effectiveness of 1,2,3-Ben...
8496
5080
ESTIMATION OF (-)-HYDROXYCITRIC ACID (HCA) IN GARCINIA LANCEAEFOLIA ROXB. USING NOVEL HPLC METHODOLOGY
ABSTRACT: (-)-Hydroxycitric acid (HCA) has been found to be the principal acid in genus Garcinia, which is a potential metabolic regulator of anti-obesity activity and inhibitor of lipogenesis. Presence of (-)-HCA as the principal acid has added importance to thegenus Garcinia. The present study deals with extraction and estimation of (-)-HCA from Garcinia lanceaefolia,collected from four administ...
8492
5256
IMPACT OF DIFFERENT CARBON SUPPLEMENT ON EXTRACTION OF C-PHYCOCYANIN (C-PC) FOLLOWED BY POLY-β-HYDROXYBUTYRATE (PHB) FROM NOSTOC MUSCORUM
The extraction of poly-β-hydroxybutyrate (PHB) and C-phycocyanin (C-PC) from Nostoc muscorum revealed that PHB yield after C-PC extraction was not found differ significantly as without C-PC extraction. Under photoautotrophic growth condition, the test cyanobacterium accumulates PHB and C-PC with a maximum yield of 40 and 57 mg l-1 respectively at the stationary phase, i.e. on day 21 of incubation...
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