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A STUDY OF EPIDEMIOLOGICAL, ETIOLOGICAL AND CLINICAL FACTORS IN HYPER-PIGMENTATION POPULATION IN NORTH GUJARAT
Background: Hyperpigmentation (HP) is a common dermatological disease. Indian population presents in a variety of dermatological pigmentation. Effects of Nutrients and metabolites factor are important for skin hyperpigmentation condition. Aims and Objectives: In this study, we aimed to evaluate the status of Haemoglobin, vitamin B12, Ferritin, and TSH levels in people with hyperpig-mentation from...
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NOVEL SULFONAMIDE SCHIFF’S BASES AND THEIR ANTIMICROBIAL ACTIVITY
In the vision of chemistry, Schiff bases are excellent ligands and play a very important role in drug discovery and development. The Schiff bases and their complexes have been reported in the literature possessing wide applications in biological, clinical, and analytical fields. In outlook of this, new Schiff bases of Sulfonamide drug were synthesized by a very simple reaction and in good yield. T...
2110
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HERBAL BASED ANTI-MICROBIAL BOOSTER FOR THE TREATMENT OF RESISTANT MYCOBACTERIUM TUBERCULOSIS
Persistent Mycobacterium tuberculosis (Mtb) attributable to resistant strains has increased the burden leading to poor quality of life to the patients. Drugs of herbal origin have been identified as potential sources of new anti-tubercular agents for the treatment of this disease and emerging resistant strains of the bacterium. In this research, therefore, five herbs/plants that have been indicate...
2110
1063
STRESS, ANXIETY AND DEPRESSION AMONG PHYSIOTHERAPY STUDENTS: A NARRATIVE REVIEW
Physiotherapy students are a valuable human resource in the realm of medicine. Mental health of physiotherapy students deteriorates due to challenging learning environment and ongoing battle to become certified healthcare providers. Anxiety, stress and depression lead to decreased productivity, poor quality of life and suicidal thoughts. This study shed light on a narrative review of the impact of...
2110
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MOLECULAR DESIGN AND ANTI-BREAST CANCER ACTIVITY OF TUPICHINOL E IN HER2+ BREAST CANCER AND EGFR SENSITIZED TO OSMERTINIB THERAPY
The epidermal growth factor receptor is a tyrosine kinase receptor and its overexpression triggers cancers. EGFR inhibition is one of the most unique and popular technique for cancer treatment. There are various approved EGFR inhibitors like osmertinib, lapatinib, afatinib, etc. Huge natural products are discovered every year and Rhamnocitrin derivative Tupichinol E obtained from the Northern Sikk...
2110
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FORMULATION, OPTIMIZATION AND EVALUATION OF FEBUXOSTAT LOADED SNEDDS FOR TREATING GOUT
Febuxostat (FXT), used for treating gout, is poorly soluble and is susceptible to enzymatic degradation when administered as tablets. The current study aims to formulate, optimize and develop a stable Liquid self-nanoemulsifying drug delivery system (L-SNEDDS) and Solid SNEDDS to improve solubility, resulting in enhanced bioavailability and further to formulate Self-Nano emulsifying Osmotic Pump T...
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INVESTIGATION OF THE ANTI-CANCER POTENCY OF NANOMEDICINE, GREEN SYNTHESIZED FROM SPIRULINA PLATENSIS, AGAINST BREAST CANCER
Breast cancer is the most common type of cancer found in women. Although considerable advances have been achieved in the diagnosis and treatment of breast cancer, medical research routinely thrives towards the development of newer technologies for the treatment of breast cancer. The current study aimed at the development of nanomedicine, in the form of silver nanoparticles from the aqueous extract...
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RELATIONSHIP BETWEEN SOCIAL SKILLS AND PROBLEM BEHAVIOUR ON ACADEMIC PERFORMANCE OF THE CHILDREN WITH MILD INTELLECTUAL DISABILITY IN INCLUSIVE EDUCATION IN TRICHY DISTRICT
Background: Children with mild intellectual disabilities demonstrate wide diversity in academic and behavioural performance. They develop adequate social, personal, and communication skills. As adults, they function in a variety of contexts. Persons with moderate intellectual disabilities have limited intellectual abilities, have problems in abstracting and generalizing, and are not ready for muc...
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FLOATING MICROSPHERES: A NOVEL EMERGING TREND IN GASTRO RETENTIVE DRUG DELIVERY
Oral Conventional dosage forms offer no control over the release of drug from the dosage form, which leads to variations in plasma drug levels; gastric emptying and gastric resident time are two another important factors that have a significant effect on the therapeutic efficacy of drug and it causes changes in the retention time of the drug. Accordingly, Floating microspheres is one of the most d...
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FORMULATION AND IN-VITRO DRUG RELEASE STUDY OF CONTROLLED RELEASE TABLET OF NIMODIPINE
At present more than 200 oral continued/controlled/ expanded/altered discharge details are accessible in the worldwide market. In India, notwithstanding, just constrained items are financially affordable. Making a stride ahead from assembling traditional dose structures, the advancement of controlled drug delivery systems. Controlled drug delivery systems have been created to improve the following...
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