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A COMPREHENSIVE INSIGHT INTO ARTIFICIAL BLOOD
In hospitals, blood transfusions are a common occurrence. Because blood-related products are limited and have a range of adverse side effects, researchers have worked on artificial blood components for nearly 40 years. It is crucial to develop effective and selective alternatives for natural blood products. Artificial blood is a useful idea in transfusion medicine wherein clearly defined compounds...
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ANTIMICROBIAL AND ANTIFUNGAL ACTIVITY OF BARK OF HARDWICKIA BINATA ROXB (FABACEAE / CAESALPINIACEAE)
Background and Objectives: This study was carried out with the objective to investigate the antibacterial and antifungal activity of the bark of Hardwickia binata Roxb. Materials and Methods: Methanolic extract of bark of Hardwickia binata Roxb. exhibited an inhibitory effect towards the pathogenic organisms. Antimicrobial activity the zone of inhibition values of methanolic extract of bark of Har...
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DIURETIC ACTIVITY OF ETHANOLIC EXTRACT OF IMPERATA CYLINDRICAL (L.) P. BEAUV. (POACEAE) LEAVES ON RAT
This work aimed to evaluate the diuretic activity of Imperata cylindrica (Poaceae) leaves on rat. The extract was administered orally at doses 100, 200 and 400 mg/kg. The 24h urine volume and its pH were measured, natriuresis and kaliuresis were dosed. The results show that I. cylindrica increases diuresis, natriuresis and kaliuresis, but doesn’t affect urine pH. Diuresis of 24 h urine increases...
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SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NOVEL QUINAZOLINE DERIVATIVES AS ACID PUMP ANTAGONISTS
Gastric acid hypersecretion is a major cause of gastric complications like hypergastrinemia, hyperhistaminemia and Zollinger-Ellison syndrome. Out of various drug treatments used, H2-receptor antagonists possess some limitations, such as the development of tolerance when used for a long period, having a short duration of action, and no complete inhibition of acid secretion in response to a meal. I...
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DEVELOPMENT AND VALIDATION OF STABILITY-INDICATING HPTLC ASSAY METHOD OF REMOGLIFLOZIN ETABONATE IN BULK AND MARKETED FORMULATION
Remogliflozin Etabonate (RE) is the latest addition to the sodium-glucose transport proteins 2 inhibitor class of drugs recently approved in India to manage type 2 Diabetes Mellitus. Literature survey revealed that no high-performance thin-layer chromatographic (HPTLC) method had been reported to date for this drug. The present work describes the development and validation of an HPTLC method for R...
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EFFECT OF HORMONAL CONTRACEPTIVES ON INFLAMMATORY BLOOD BIOMARKER C-REACTIVE PROTEIN
To compare the effect of combined oral contraceptive (COC) and progesterone-only injectable contraceptive (PIC) on the inflammation, we recruited 47 female participants (16 to 43 years old) in 3 groups: control participants (n=10), COC users (n=16) and PIC users (n=21). Using ELISA and Latex agglutination methods, we measured the effect of hormonal contraceptives on the inflammatory blood biomarke...
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SCREENING OF NATURAL PIGMENTS FROM SEAWEED KAPPAPHYCUS ALVAREZII AND ITS EFFICACY IN PHARMACEUTICAL PRODUCTS
This paper focused on research on seaweed contains good nutritional source of protein, carbohydrate, pigments, vitamins, and antioxidants and has low lipid content. The source of natural substances has considered more efficient bio-molecules in building immunity and improving resistance to cancer development, prevent infections were analyzed. Classical biochemical methods were applied for extracti...
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COMPARISON OF THREE TECHNIQUES FOR THE DIAGNOSIS OF MALARIA IN RESOURCE-LIMITED SETTINGS: A MINI-REVIEW
Objective of this article is to review three techniques, routinely used rapid diagnostic tests (lateral flow immune chromatography) versus nucleic acid amplification test (NAT) versus Paper-based microfluidics for DNA diagnostics of Malaria, as diagnostic tests in detecting malarial infection among febrile illnesses, suspected of malaria. The major constraint for implementing NAT as a routine scre...
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MORPHOMETRY OF HUMAN SCAPULA GLENOID FOSSA AND ITS SURGICAL ANATOMY: AN OBSERVATIONAL STUDY IN EASTERN ODISHA
Introduction: Scapulae bear a shallow articular concave fossa commonly known as glenoid cavity that accommodates the head of the humerus to form a shoulder joint. The size and shape of glenoid fossa is highly variable; hence, knowledge about morphological measurements is invariably essential for surgery and artificial prosthesis pertaining to shoulder joint pathology. Aim: Glenoid fossa morphome...
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EVALUATION OF DETRIMENTAL FACTORS OF DRINKING WATER AND THE EFFECT OF BLOOD GLUCOSE LEVELS AND ANXIETY STATUS: AN EXPERIMENTAL STUDY IN WISTAR ALBINO RATS USING ELEVATED PLUS MAZE
This study is focused on evaluating the detrimental factors of drinking water and its relation to blood glucose level and anxiety status of non-stressed experimental rats. The study was conducted on 30 adult Wistar albino rats. The control group was treated with filtered water by reverse osmosis unit, and test 1, test 2, test 3, and test 4 groups were treated with well water from rural area 1, r...
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