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IMPORTANCE OF ADHATODA VASICA NEES IN TRADITIONAL SYSTEM OF MEDICINES: A REVIEW
Adhatoda vasica Nees, belonging to the Acanthaceae family and commonly referred to as vasa or vasaka, is a prominent herbal remedy within Ayurvedic, Unani, and Homeopathic medicine systems. Vasaka is widely distributed across India and tropical regions in Southeastern Asia. This plant is recognized for its rich reservoir of phytoconstituents, notably vitamin C and various alkaloids. Alkaloids such...
2072
1345
EFFECT OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS ON RESERPINE INDUCED PARKINSONISM IN RATS
Parkinson's disease is a chronic progressive neuro-degenerative disease caused by selective degeneration of dopaminergic neurons in the dense part of the substantia nigra pars compacta. It is characterized by motor and non-motor symptoms, especially the gradual reduction of postural symptoms, instability, tremor and memory impairment, local neuron loss, which mainly occurs in the substantia nigra....
2070
1012
STUDIES ON FORMULATION AND EVALUATION OF IBUPROFEN MATRIX DRUG DELIVERY SYSTEM BY USING “BEE PROPOLIS” (APIS MELLIFERA L.)
Ibuprofen is a Non-steroidal anti-inflammatory (NSAID) class drug and is used to treat pain, minor aches, fever, inflammation, and arthritis. Ibuprofen has an oral dose of 300 mg minimum and 3200 mg maximum in a day and is the main reason for the increase in its dosing frequency; many of the Ibuprofen formulations are of three times a day dosing and is the main reason for the development of such a...
2070
1408
COMPARATIVE STUDY OF THE PROTECTIVE EFFECT OF THE LEAVES OF MURRAYA KOENIGII AND CENTELLA ASIATICA IN EXPERIMENTALLY INDUCED INFLAMMATORY BOWEL DISEASE IN ANIMALS
Ulcerative colitis was defined as a common intestinal infla-mmatory disease characterized by upregulation of pro-inflammatory cytokines and oxidative stress. The leaves of Murraya koenigii and Centella asiatica had been used in traditional medicine to treat the disease. The present study aimed to perform a comparative protective efficacy evaluation between Murraya koenigii and Centella asiatica on...
2068
1018
IMPACT OF CHAT GPT IN PHARMACEUTICAL EDUCATION
Introduction: This paper will provide an overview of the uses, advantages and disadvantages of using ChatGPT in the pharmacy. A new era of personalised and interactive learning is beginning in pharmaceutical education because of ChatGPT (Generative Pre-trained Transformer). Through the use of AI technology, ChatGPT provides adaptive tutoring that enables students to advance at their own speed and ...
2068
1031
TO EVALUATE THE CHEMICAL CONSTITUENTS OF SHODITHA (PURIFIED) AND ASHODHITHA (RAW) DATURA METEL LINN ROOT – A ANALYTICAL STUDY
Datura (Datura metel Linn.) is a herbaceous leafy annual and short-lived plant of the Solanaceae family. It's commonly known as Angel's trumpet, Devils apple, Jimson weed, stinkweed, and Thorn apple. The traditional system of medicine enlightened the importance of Datura metel Linn. of its great medicinal value. The roots, leaves and flowering tops have been used in India for their narcotic and an...
2067
1092
IN-SILICO ANALYSIS OF MTA1 AS DRUG TARGET AGAINST NATURAL ANTIOXIDANTS
The protein MTA1 with histone deacetylase activity is a member of the nucleosome remodeling complex encoded by the mta1 gene is frequently overexpressed in biologically aggressive epithelial neoplasms. MTA1 is a nuclear co-regulatory molecule that is highly expressed in many cancers and correlates with tumor metastasis and progression. MTA1 alters signaling events in the tumor micro-environment. M...
2067
1123
EFFECTS OF POLY-UNSATURATED FATTY ACIDS ON LEUKOCYTE TELOMERE LENGTH AND INFLAMMATORY MARKERS IN D-GALACTOSE TREATED WISTAR ALBINO MALE RATS
The present study aimed at analyzing the effects of PUFA in D-galactose treated Wistar albino male rats by determining leukocyte telomere length using real-time quantitative PCR, Il-6, and high sensitive C-RP levels estimation using ELISA. D-galactose is administered for 42 days orally (100 mg/kg), and on 43rd-day, blood is collected from tail vein and plasma is separated and subjected for IL-6 an...
2066
1257
FORMULATION AND CHARACTERIZATION OF IN-SITU GEL FOR OPHTHALMIC FORMULATION CONTAINING CIPROFLOXACIN HYDROCHLORIDE
Ophthalmic delivery for eye drops which currently cover to 90% of available ocular dosage forms are ideal for the treatment of eye diseases but having limitations of poor therapeutic response and low bioavailability. Objectives: The objectives of present research was to develop of formulation and characterize sustained release in-situ ocular gels containing ciprofloxacin hydrochloride using pH ind...
2066
1609
DRUG UTILIZATION TRENDS OF ORAL ANTI-DIABETIC AGENTS AMONG DIABETES MELLITUS TYPE 2 PATIENTS IN A TERTIARY CARE HOSPITAL
Diabetes is a group of metabolic diseases and emerged as a major healthcare problem. According to the International Diabetes Federation (IDF), India has a large number of people suffering from diabetes, which will increase to almost 101 million by the year 2030. The pharmacotherapies of diabetes mellitus are diversified in their mechanism of action, safety profiles and tolerability. Drug utilizati...
2064
966