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NEURODEGENERATIVE DISORDERS: ROLE OF MEDICINAL PLANTS IN TREATMENT
Neurons are the nervous system's basic components that involve the spinal cord and brain. Neurons do not usually replicate or substitute them because the body cannot replace them as they get impaired or die. Neurological conditions are untreatable and disabling diseases that result in irreversible deterioration/death of the human brain's nerve cells or neurons. Treating these conditions with exten...
2054
1138
SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF SOME NOVEL TRIAZOLE DERIVATIVES
Triazole is a diunsaturated heterocyclic compound that contains two nitrogen groups as heteroatoms. In the present study, an attempt was made to synthesize various derivatives of substituted 1, 2, 4-triazol-3-yl) benzene-1-ol and assess their antimicrobial efficiency. The synthesized compounds were subjected to physical characterization and spectral analysis by IR and NMR for structure elucidation...
2054
1079
TO EVALUATE THE CHEMICAL CONSTITUENTS OF SHODITHA (PURIFIED) AND ASHODHITHA (RAW) DATURA METEL LINN ROOT – A ANALYTICAL STUDY
Datura (Datura metel Linn.) is a herbaceous leafy annual and short-lived plant of the Solanaceae family. It's commonly known as Angel's trumpet, Devils apple, Jimson weed, stinkweed, and Thorn apple. The traditional system of medicine enlightened the importance of Datura metel Linn. of its great medicinal value. The roots, leaves and flowering tops have been used in India for their narcotic and an...
2053
1083
REVEALING SILYMARIN: HPTLC METHOD DEVELOPMENT AND VALIDATION
Silymarin, an intricate blend of flavonolignans obtained from Silybum marianum, or milk thistle, has drawn a lot of interest because of its possible medical uses. This study reports on the development and validation of an analytical technique that employs high performance thin layer chromatography (HPTLC) to estimate silymarin in pharmaceutical dosage forms (tablet) and bulk drug. Chloroform: meth...
2053
1215
CYTOTOXICITY, ANTIMICROBIAL ACTIVITIES AND CHEMICAL PROPERTIES OF TEN PLANTS FROM THE BENIN PHARMACOPOEIA USED FOR ORAL CARE
This study aims to valorizeten medicinal plants traditionally used for oral care in Benin by producing scientific data on their toxicities, antimicrobial activities, and chemical properties. The ten medicinal plants (Zanthoxylum zanthoxyloides, Vitellaria paradoxa, Prosopis africana, Dialium guineense, Pseudocedrela kotschyi, Parkia biglobosa, Azadirachta indica, Diospyros mespiliformis, Anogeissu...
2052
887
IMPACT OF CHAT GPT IN PHARMACEUTICAL EDUCATION
Introduction: This paper will provide an overview of the uses, advantages and disadvantages of using ChatGPT in the pharmacy. A new era of personalised and interactive learning is beginning in pharmaceutical education because of ChatGPT (Generative Pre-trained Transformer). Through the use of AI technology, ChatGPT provides adaptive tutoring that enables students to advance at their own speed and ...
2052
1030
NANOSTRUCTURED LIPID CARRIERS –A PROMISING CARRIER FOR IMPROVING ORAL BIOAVAILABILITY OF DRUGS
To deliver both conventional as well as novel drugs, the oral route was considered as the most preferable one because it reduces patient’s non-compliance, well accepted by the patients, and can also eliminate the discomfort and pain accompanied by parenteral preparations. Even while oral formulations offer numerous advantages, several drawbacks substantially affect bioavailability. In recent yea...
2051
1415
IN-VITRO CYTOTOXIC STUDY ON ROOT EXTRACTS OF APAMA SILIQUOSA LAMK.
The demand for herbal medicines is growing at a drastic rate due to their improved pharmacological actions, minimal side effects, and cost-effectiveness. The ever-increasing cost of chemotherapy ruined the economic stability of many families. This led to the discovery of herbal medicines for cancer treatment. Tribes of Western Ghats have been using the roots of Apama siliquosa for cytotoxic activi...
2051
1178
IN-VITRO BIOACTIVE POTENTIAL OF ENDOPHYTIC FUNGI CURVULARIA LUNATA ISOLATED FROM MEDICINAL PLANT FICUS RELIGIOSA
Several studies undertaken in the recent past have demonstrated that endophytic fungi are capable of producing a number of important bioactive secondary metabolites, hitherto known only from plants, thereby raising the potential of using endophytes as alternative sources for these metabolites. Occasionally, the compounds produced by endophytic fungi are similar to those produced by the respective ...
2050
1054
ANTI-INFLAMMATORY, ANTI-CANDIDAL ACTIVITY AND IN-SILICO PREDICTION OF PHARMACOKINETIC PROPERTIES OF NARDOSTACHYS JATAMANSI
The earlier reports on Nardostachys jatamansi show contain a various class of chemical constituents that have influenced the anti-inflammatory and anti-candidal activities. The present study reports the evaluation of anti-inflammatory and anti-candidal activities of N. jatamansi and also studies pharmacokinetic properties using in-silico model. In ongoing research work, we used individual extracts...
2050
1012