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FORMULATION AND EVALUATION OF SOLID-SELF NANO EMULSIFYING DRUG DELIVERY SYSTEM OF FAMOTIDINE
The main objective of the study was to formulate and evaluate solid self nano emulsifying drug delivery systems (SNEDDS) of famotidine (BCS class-IV drug), a histamine receptor antagonist used in case of ulcers, Zollinger-ellison syndrome. Liquid SNEDDS was formulated using oils like oleic acid, arachis oil, surfactants like Tween 20, Tween 80, etc., and co-surfactants like Transcutol-P, polyethyl...
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QUANTITATIVE ESTIMATION OF MINERAL CONTENT FROM EDIBLE FLOWERS OF ALLIUM CEPA, CUCURBITA MAXIMA AND CARICA PAPAYA: A COMPARATIVE STUDY
Edible flowers have been an integral part of human nutrition for centuries, being used as garnishes of individual dishes and also consumed fresh. This study determines and compares the essential and trace mineral composition of the three edible flowers of Allium cepa (onion), Carica papaya (papaya) and Cucurbita maxima (pumpkin) with four other commonly consumed edible flowers. Also, a comparative...
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FLOWERS – THE NOBLE ROLE OF THE MOST BEAUTIFUL, PLENTIFUL, BUT NEGLECTED BIO-RESOURCE IN INDIA
The Greek words “angeion” (vessel) and “sperma” (seed) constitute angiosperm which together define enclosed seeds. The angiosperms differ from closely related gymnosperms in seed being naked and not enclosed within a fruit. Moreover, angiosperms are distinguished plants having colorful flowers. Having originated about 130 million years ago, the flowering plants are more diverse and largest...
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IN-VITRO ANTHELMINTIC EFFECTS OF MEDICINAL PLANT CASSIA FISTULA EXTRACT ON THE TEGUMENT OF FASCIOLA GIGANTICA BY LIGHT MICROSCOPE
The efficacy of alcoholic Cassia fistula leaves extract on the tegument of Fasciola gigantic was studied by light microscopy. Live liver fluke Fasciola gigantica parasites were collected from the infected liver and bile duct of freshly slaughtered domestic goat (Capra hircus) at the local zoo abattoir in Udaipur. Liver flukes F. gigantica were maintained in 0.9% physiological saline and divided in...
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A STUDY ON THE NOSE TO BRAIN DRUG DELIVERY SYSTEM
Drugs have been controlled by the nasal route for remedial & therapeutic use since ancient times. Enthusiasm & importance for the basic impacts of drugs directed via the nasal route has developed to last decades. Intra-nasal drug organization provides an attractive substitute for achieving the important beneficial impacts of drugs virtually similar to the parenteral route, that may be impr...
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COMPLETENESS ASSESSMENT OF HANDWRITTEN MEDICAL PRESCRIPTIONS IN SOUTHEAST KINSHASA COMMUNITY PHARMACIES
Medical prescription carefully conceived is essential to provide effective health care to the patient. It is a medicolegal document that should be legible, clear and complete. However, several studies have shown that prescription errors remain common worldwide, particularly in low-income countries the such Democratic Republic of Congo. This study aimed to explore the completeness of medical prescr...
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NEUROPROTECTIVE EFFECT OF MADHUCA LONGIFOLIA LEAF EXTRACT AGAINST COLCHICINE: AN EXPERIMENTAL STUDY ON COGNITIVE DYSFUNCTION AND BIOCHEMICAL ALTERATIONS IN MICE
The goal of the research was to explain as a cognition enhancer the traditional claim of Madhuca longifolia (Sapotaceae) leaves. Dementia was activated by intracerebrovascular colchicine administration for 28 days. Madhuca longifolia leaves ethanolic extract was evaluated in mice for cognition-enhancing activity in colchicine-induced dementia using elevated plus maze (EPM), actophotometer, and bio...
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DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR SIMULTANEOUS DETERMINATION OF GLIPIZIDE AND MOMORDICININ IN RAT PLASMA
Momordicinin (MMR) is a major triterpenoid compound from Momordica charantia Linn fruit having antidiabetic potential, whereas glipizide (GPZ) is a well-known molecule in treatment of diabetes mellitus. The primary objective of the study is to develop and validate a simultaneous RP-HPLC method for upcoming pharmacokinetic studies to analyze herb-drug interactions. The study uses the protein precip...
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THE PHARMACOLOGICAL ACTIONS OF IRIFLOPHENONE-3-C-β-D GLUCOSIDE: AN OVER VIEW
Iriflophenone 3-C-β-D glucoside is a Benzophenone derivative which can be obtained from various plant sources like Aquilaria crassna, A. sinensis, A. malaccensis, Cyclopia genistoides, Mangifera indica, Dryopteris ramosa etc. It can act as an important herbal active constituent as it has various pharmacological actions, such as Antidiabetic, anti-inflammatory, antioxidant, and antimicrobial agent...
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MICROCYSTIN-BASED NANO DRUG FROM ANABAENA CYLINDRICA FOR TREATMENT OF HEPATOCELLULAR CARCINOMA
Hepatocellular carcinoma (HCC) is liver cancer characterized by high prevalence and low survival rate. Hence, there is an urgent need to screen resources to develop therapeutic drugs to treat patients suffering from HCC. In this context, the current study involves developing a microcystin conjugated nano-drug from cyan bacteria Anabaena cylindrica to target the tumor liver cells. The microcystin m...
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