Most Popular
CYTOTOXICITY, ANTIMICROBIAL ACTIVITIES AND CHEMICAL PROPERTIES OF TEN PLANTS FROM THE BENIN PHARMACOPOEIA USED FOR ORAL CARE
This study aims to valorizeten medicinal plants traditionally used for oral care in Benin by producing scientific data on their toxicities, antimicrobial activities, and chemical properties. The ten medicinal plants (Zanthoxylum zanthoxyloides, Vitellaria paradoxa, Prosopis africana, Dialium guineense, Pseudocedrela kotschyi, Parkia biglobosa, Azadirachta indica, Diospyros mespiliformis, Anogeissu...
2058
890
IN-VITRO CYTOTOXIC STUDY ON ROOT EXTRACTS OF APAMA SILIQUOSA LAMK.
The demand for herbal medicines is growing at a drastic rate due to their improved pharmacological actions, minimal side effects, and cost-effectiveness. The ever-increasing cost of chemotherapy ruined the economic stability of many families. This led to the discovery of herbal medicines for cancer treatment. Tribes of Western Ghats have been using the roots of Apama siliquosa for cytotoxic activi...
2058
1184
SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF SOME NOVEL TRIAZOLE DERIVATIVES
Triazole is a diunsaturated heterocyclic compound that contains two nitrogen groups as heteroatoms. In the present study, an attempt was made to synthesize various derivatives of substituted 1, 2, 4-triazol-3-yl) benzene-1-ol and assess their antimicrobial efficiency. The synthesized compounds were subjected to physical characterization and spectral analysis by IR and NMR for structure elucidation...
2058
1083
ANTI-INFLAMMATORY, ANTI-CANDIDAL ACTIVITY AND IN-SILICO PREDICTION OF PHARMACOKINETIC PROPERTIES OF NARDOSTACHYS JATAMANSI
The earlier reports on Nardostachys jatamansi show contain a various class of chemical constituents that have influenced the anti-inflammatory and anti-candidal activities. The present study reports the evaluation of anti-inflammatory and anti-candidal activities of N. jatamansi and also studies pharmacokinetic properties using in-silico model. In ongoing research work, we used individual extracts...
2058
1013
HYPERTROPHIC CARDIOMYOPATHY
Hypertrophic cardiomyopathy (HCM) is a genetic disorder that is characterized by left ventricular hypertrophy unexplained by secondary causes and a nondilated left ventricle with preserved or increased ejection fraction. It is commonly asymmetrical, with the most severe hypertrophy involving the basal interventricular septum. The histological features of HCM include myocyte hypertrophy and disarra...
2057
1064
AN ANTIPLASMODIAL ACTIVITY OF LEAVES EXTRACTS OF CASSIA OBTUSIFOLIA AND HYPTIS SUAVEOLENS FROM GHANA
A number of the population in developing countries use herbs and herbal products to treat various diseases including malaria. However, most of them have not been evaluated for their efficacy and toxicity and their use is not standardized in some instances. Poly-herbal extracts may yield better treatment outcomes compared to extracts from a single plant due to the combined effects of bioactive comp...
2057
1083
NANOSUSPENSION – A PROMISING TECHNIQUE FOR POORLY SOLUBLE DRUGS
Most pharmaceutical drugs create problems during formulation as they are insoluble or poorly soluble in aqueous and non-aqueous mediums. It was proved that reducing the drug particle size increases the drug's Solubility, Dissolution and Bioavailability. Many conventional techniques may be used, but the desired amount of particle size may not be achieved, and Solubility, Dissolution and Bioavailabi...
2056
1071
NANOSTRUCTURED LIPID CARRIERS –A PROMISING CARRIER FOR IMPROVING ORAL BIOAVAILABILITY OF DRUGS
To deliver both conventional as well as novel drugs, the oral route was considered as the most preferable one because it reduces patient’s non-compliance, well accepted by the patients, and can also eliminate the discomfort and pain accompanied by parenteral preparations. Even while oral formulations offer numerous advantages, several drawbacks substantially affect bioavailability. In recent yea...
2056
1418
ANTI-ALBUMIN DENATURATION, TRYPSIN INHIBITION AND RBC MEMBRANE STABILIZATION AS POSSIBLE MECHANISM FOR ANTI-INFLAMMATORY ACTIVITY OF METHANOL LEAF EXTRACTS OF SOLANUM SPECIES
In view of rising concern of problem associated with synthetic drugs against inflammation, current research has been focused towards safer, effective and natural compounds. Hence, we aimed at assessing the anti-inflammatory effect of four plants from Solanum species (S. seaforthianum, S. diphyllum, S. sisymbriifollium and S. anguivi) through albumin denaturation assay, trypsin inhibition and RBC m...
2056
1338
PUNICA GRANATUM L. WINE – HEALTH BENEFITS
Punica granatum L. is the reddish colour fruit, commonly known as Pomegranate. It is known to have many health and therapeutic benefits which can be used as agent. The pomegranate juice is also used to prepare wine. The present study was carried out to determine the optimum fermentation parameters of pomegranate wine preparation. The antimicrobial and antioxidant activity of various wine preparati...
2056
720