Most Popular
FORMULATION AND EVALUATION OF FICUS BENGHALENSIS LOADED CANDY FOR TOOTHACHE
People utilise plants regularly all around the world for the treatment and prevention of a wide range of illnesses. One abundant plant found in India is the banyan tree, Ficus benghalensis Linn. Oral and dental hygiene is the primary factor of a human being to lead a healthy life. The aim of this study is to design Ficus benghalensis Linn. candy to improve patient oral health, toothache, and accep...
2128
941
EVALUATION OF CYANIDIN-3-O-GLUCOSIDE FROM DIFFERENT BLACK RICE VARIETIES OF MANIPUR UTILIZING FTIR SPECTROSCOPY AND HPTLC METHOD
Black rice is a rice species, Oryza sativa Linne (Gramineae), which is sticky, high in nutrients, and primarily grown in Asia. In recent years, the health benefits of black rice varieties have been reported due to the presence of a bioactive compound, anthocyanin, which has highly potent activity with high macronutrients. The present study aimed to evaluate and quantify the metabolites, focusing o...
2128
1005
DEVELOPMENT AND EVALUATION OF CYCLODEXTRIN BASED NANOSPONGE LOADED TAZORETENE GEL
The objective of the present study was to develop cyclodextrin-based nanosponge based topical gel of tazoretene using cross-linker diphenylcarbonate and Carbopol® Ultrez 10 NF polymer. The β-Cyclodextrin nanosponges were prepared using various concentrations of β-Cyclodextrin and diphenyl carbonate and characterized. Based on evaluation parameters the β-Cyclodextrin nanosponges formulations (N...
2127
1494
SYNERGISTIC CONVERGENCE: EXPLORING COMBINATIONS OF DIVERSE PHYSIOLOGICAL ACTIVITIES – A REVIEW
The development of effective therapeutic strategies for various remedial conditions often involves the exploration of synergistic interaction between two pharmacophores. The most frequent methods for multidrug therapy combining two or more active ingredients into a single, and creating hybrid molecular entities that can modulate numerous targets interaction gives a synergistic effect. As a result,...
2127
1555
REGULATION OF RAS-INDUCED HYPHAL FORMATION BY HISTONE ACETYLASE GCN5 IN CANDIDA ALBICANS
Candida albicans is the leading cause of superficial and systemic fungal infections in human beings and is very common in people with a weakened immune system. It can grow either as budding yeast, a pseudohyphae form, or in a true hyphal form, and the ability to switch between these three forms is important for its pathogenicity. To date, an in-depth study on the relationship between histone modif...
2127
1131
PHARMACOGNOSTICAL AND PHYTOCHEMICAL INVESTIGATION OF FUMARIA PARVIFLORA LAM.
The present paper deals with the pharmacognostical and phytochemical investigation of Fumaria parviflora Lam. whole plant. The qualitative and quantitative phytochemical analysis was carried out for the important bioactive constituents present in Fumaria parviflora Lam. (whole plant) in its Hydroalcoholic extract. The preliminary phytochemical analysis showed the presence of alkaloids, phenols, fl...
2124
1097
HERBAL BASED ANTI-MICROBIAL BOOSTER FOR THE TREATMENT OF RESISTANT MYCOBACTERIUM TUBERCULOSIS
Persistent Mycobacterium tuberculosis (Mtb) attributable to resistant strains has increased the burden leading to poor quality of life to the patients. Drugs of herbal origin have been identified as potential sources of new anti-tubercular agents for the treatment of this disease and emerging resistant strains of the bacterium. In this research, therefore, five herbs/plants that have been indicate...
2124
1065
REVIEW ON ACTIVITY OF CANNABIS TREATMENT ON PARKINSON’S DISEASE
As new treatments and medication are growing rapidly, neurologists are also toward expanding treating patients with idiopathic Parkinson's disease and facing questions regarding cannabis as a treatment elective, particularly for levodopa-safe Parkinson's symptoms. Cannabinoids compounds like delta-9-tetrahydrocannabinol (THC) and Cannabidiol (CBD) are the most abundant chemicals present. Whereas T...
2123
1085
SYNTHESIS AND BIOLOGICAL EVALUATION OF NOVEL CHALCONES WITH METHANE-SULFONYL END AS POTENT ANALGESIC AND ANTI-INFLAMMATORY AGENTS
In the present study, eleven new chalcones bearing a methanesulfonyl group at para position have been synthesized by the condensation of 4-methylsulphonylacetophenone with different para-substituted aromatic aldehydes. The structures of the newly synthesized molecules were elucidated by spectroscopic methods such as as1H NMR, 13C NMR, and mass. These compounds were screened for their anti-inflamma...
2122
1025
NOVEL SULFONAMIDE SCHIFF’S BASES AND THEIR ANTIMICROBIAL ACTIVITY
In the vision of chemistry, Schiff bases are excellent ligands and play a very important role in drug discovery and development. The Schiff bases and their complexes have been reported in the literature possessing wide applications in biological, clinical, and analytical fields. In outlook of this, new Schiff bases of Sulfonamide drug were synthesized by a very simple reaction and in good yield. T...
2122
1264