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CEREBROVASCULAR ACCIDENT ASSOCIATED HEMIPARESIS AND HEMIPLEGIA: COPING STRATEGIES AND SUPPORT
Background: Cerebrovascular Accident (CVA) ranks as the third leading cause of mortality globally and contributes significantly to chronic adult disabilities. Hemiparesis, the most prevalent post-stroke mobility impairment, affects approximately 75% of stroke survivors, substantially reducing their quality of life. This study aims to investigate CVA-associated Hemiparesis and Hemiplegia, focusing ...
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FORMULATION AND EVALUATION OF SOLID-SELF NANO EMULSIFYING DRUG DELIVERY SYSTEM OF FAMOTIDINE
The main objective of the study was to formulate and evaluate solid self nano emulsifying drug delivery systems (SNEDDS) of famotidine (BCS class-IV drug), a histamine receptor antagonist used in case of ulcers, Zollinger-ellison syndrome. Liquid SNEDDS was formulated using oils like oleic acid, arachis oil, surfactants like Tween 20, Tween 80, etc., and co-surfactants like Transcutol-P, polyethyl...
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SARS COV, MERS COV, SARS COV-2 AND TREATMENTS: A BIBLIOMETRIC ANALYSIS
As the incidences of Coronavirus (SARS CoV-2) infections have been increasing at a rapid pace, the need for its containment and treatment has taken center stage for numerous research institutions. The similarity of SARS CoV-2 with that of SARS CoV has led to a jumpstart in the research activities on corona-virus on the same. The number of research articles appearing since the time SARS CoV-2 was d...
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PHARMACOGNOSTICAL EVALUATION OF TERMINALIA CHEBULA FRUIT EXTRACT AGAINST RESPIRATORY TRACT INFECTIOUS PATHOGENS
To evaluate the antibacterial activity of methanolic extract of Terminalia chebula, commonly called Haritaki was tested against respiratory tract infection-causing bacteria. The antibacterial activities were assessed by agar well diffusion, broth dilution and time-kill methods. It showed the best antibacterial activity against Klebsiella pneumoniae among the tested respiratory infection-causing ba...
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SCREENING OF ANTI-BACTERIAL ACTIVITY OF BROWN SEAWEEDS FROM SOUTH EAST COAST OF INDIA
Three different species of seaweeds collected from south east coast of India such as Sargassum plagiophyllum, Padina gymnospora and Turbinaria conoides for evaluating anti-bacterial activity against selected gram-positive and gram-negative bacteria. Extracts prepared using solvents namely hexane, ethyl acetate, methanol, and water against human pathogenic strains of Proteus vulgaris, Staphylococcu...
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BIOSYNTHESIS AND CHARACTERIZATION OF GOLD NANOPARTICLES FROM CEIBA PENTANDRA (L.) GAERTN BARK AND EVALUATION OF ITS ANTIBACTERIAL AND ANTICANCER ACTIVITY
The present investigation was aimed at synthesis, characterization and in-vitro antibacterial and anticancer activities of synthesized gold nanoparticles using bark extract of Ceiba pentandra (L.) Gaertn. The synthesized AuNPs were confirmed by a UV-vis spectrometer through observing the surface plasmon resonance peak at 535 nm. Various other techniques, such as Fourier transform infrared spectros...
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HOME REMEDIES, DIETARY AND LIFESTYLE CHANGES DURING COVID-19 PANDEMIC
December 2019 has become one of the most surprising days in the whole world in light of the flare-up of a most infectious sickness brought about by novel Covid or Severe Acute Respiratory Syndrome Corona virus 2 (SARS-CoV-2). This study is conducted to assess the benefits of the use of home remedies to prevent the cause of Covid-19 and evaluate the assessment of dietary changes and physical activi...
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ABELMOSCHUS ESCULENTUS L. MITIGATES NAFLD PATHOLOGIC PHENOTYPES IN C57BL/6J MOUSE MODEL
Purpose: Lifestyle modification is recommended as a primary strategy for the management of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH). Recently, metabolic regulations of diets containing parts of Abelmoschus esculentus (okra) were investigated using the NAFLD mouse model. Methods: Five groups of C57BL/6J mice (n = 6) were arranged. Each received a distinct d...
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ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF ASCOMYCIN CONTENT IN TACROLIMUS API BY USING RP HPLC
A quick and affordable analytical method validation for the determination of Ascomycin content in Tacrolimus API by HPLC UV-detector was developed with respect to the accuracy, precision, linearity, selectivity, robustness, limit of quantification, limit of detection, according to ICH guidelines. The extraction of samples was performed using HPLC –LC Solutions Chemstation system manufactured by ...
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IN-VITRO EVALUATION OF THE TOTAL PHENOLIC, FLAVONOID CONTENTS AND FREE RADICAL SCAVENGING POTENTIAL OF RUMEX HASTATUS
Objective: The aim of this study was to screen various solvent extracts of leaves of Rumex hastatus to display in-vitro antioxidant activity, total phenolic, and flavonoid contents in order to find possible sources for future novel antioxidants in food and pharmaceutical formulations. Materials and Methods: A detailed study was performed on antioxidant activity of various Rumex hastatus leaves ext...
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