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PHARMACOGNOSTICAL EVALUATION OF TERMINALIA CHEBULA FRUIT EXTRACT AGAINST RESPIRATORY TRACT INFECTIOUS PATHOGENS
To evaluate the antibacterial activity of methanolic extract of Terminalia chebula, commonly called Haritaki was tested against respiratory tract infection-causing bacteria. The antibacterial activities were assessed by agar well diffusion, broth dilution and time-kill methods. It showed the best antibacterial activity against Klebsiella pneumoniae among the tested respiratory infection-causing ba...
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BIOSYNTHESIS AND CHARACTERIZATION OF GOLD NANOPARTICLES FROM CEIBA PENTANDRA (L.) GAERTN BARK AND EVALUATION OF ITS ANTIBACTERIAL AND ANTICANCER ACTIVITY
The present investigation was aimed at synthesis, characterization and in-vitro antibacterial and anticancer activities of synthesized gold nanoparticles using bark extract of Ceiba pentandra (L.) Gaertn. The synthesized AuNPs were confirmed by a UV-vis spectrometer through observing the surface plasmon resonance peak at 535 nm. Various other techniques, such as Fourier transform infrared spectros...
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DEVELOPMENT AND EVALUATION OF HYDROCORTISONE-LOADED NIOSOMAL GEL
Objective: The present research work was to formulate optimize and evaluate hydrocortisone-loaded niosomal gel for the management of rheumatoid arthritis. Method: Niosomal gel was successfully prepared by lipid-thin film hydration process and optimized by using 23 full factorial designs using three independent variables (tween 80 concentration, cholesterol concentration, and sonication time) and t...
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ANALYTICAL METHOD DEVELOPMENT AND VALIDATION OF ASCOMYCIN CONTENT IN TACROLIMUS API BY USING RP HPLC
A quick and affordable analytical method validation for the determination of Ascomycin content in Tacrolimus API by HPLC UV-detector was developed with respect to the accuracy, precision, linearity, selectivity, robustness, limit of quantification, limit of detection, according to ICH guidelines. The extraction of samples was performed using HPLC –LC Solutions Chemstation system manufactured by ...
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HOME REMEDIES, DIETARY AND LIFESTYLE CHANGES DURING COVID-19 PANDEMIC
December 2019 has become one of the most surprising days in the whole world in light of the flare-up of a most infectious sickness brought about by novel Covid or Severe Acute Respiratory Syndrome Corona virus 2 (SARS-CoV-2). This study is conducted to assess the benefits of the use of home remedies to prevent the cause of Covid-19 and evaluate the assessment of dietary changes and physical activi...
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SCREENING OF ANTI-BACTERIAL ACTIVITY OF BROWN SEAWEEDS FROM SOUTH EAST COAST OF INDIA
Three different species of seaweeds collected from south east coast of India such as Sargassum plagiophyllum, Padina gymnospora and Turbinaria conoides for evaluating anti-bacterial activity against selected gram-positive and gram-negative bacteria. Extracts prepared using solvents namely hexane, ethyl acetate, methanol, and water against human pathogenic strains of Proteus vulgaris, Staphylococcu...
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A REVIEW ON HUMAN IMMUNODEFICIENCY VIRUS INFECTION AND RETROVIRUSES
Human Immunodeficiency Virus or HIV is generally known, is a unique type of virus (retrovirus). HIV is a slow virus that causes acquired immunodeficiency syndrome, a human condition in which the progressive failure of the immune system allows opportunistic infections and life-threatening cancers to spread. Retroviruses are a single positive susceptible RNA virus with a DNA mediator and binding par...
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IN-VITRO EVALUATION OF THE TOTAL PHENOLIC, FLAVONOID CONTENTS AND FREE RADICAL SCAVENGING POTENTIAL OF RUMEX HASTATUS
Objective: The aim of this study was to screen various solvent extracts of leaves of Rumex hastatus to display in-vitro antioxidant activity, total phenolic, and flavonoid contents in order to find possible sources for future novel antioxidants in food and pharmaceutical formulations. Materials and Methods: A detailed study was performed on antioxidant activity of various Rumex hastatus leaves ext...
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CEREBROVASCULAR ACCIDENT ASSOCIATED HEMIPARESIS AND HEMIPLEGIA: COPING STRATEGIES AND SUPPORT
Background: Cerebrovascular Accident (CVA) ranks as the third leading cause of mortality globally and contributes significantly to chronic adult disabilities. Hemiparesis, the most prevalent post-stroke mobility impairment, affects approximately 75% of stroke survivors, substantially reducing their quality of life. This study aims to investigate CVA-associated Hemiparesis and Hemiplegia, focusing ...
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FORMULATION AND EVALUATION OF SOLID-SELF NANO EMULSIFYING DRUG DELIVERY SYSTEM OF FAMOTIDINE
The main objective of the study was to formulate and evaluate solid self nano emulsifying drug delivery systems (SNEDDS) of famotidine (BCS class-IV drug), a histamine receptor antagonist used in case of ulcers, Zollinger-ellison syndrome. Liquid SNEDDS was formulated using oils like oleic acid, arachis oil, surfactants like Tween 20, Tween 80, etc., and co-surfactants like Transcutol-P, polyethyl...
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