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COLD-ACTIVE EXO-INULINASE ENZYME: ISOLATION AND SCREENING OF ENDOPHYTIC MICROBES FROM FRUITS
Microbial inulinases have a great potential for industrial use in the production of fructose from inulin. Optimization of the growth parameters of the microbes is essential to obtain inulinase in sufficient quantity. The present work aims to obtain inulinase from different fruits of endophytic bacteria and optimize its growth parameters. In a total of 22 isolates and among them, each one isolates ...
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PREVALENCE AND KNOWLEDGE ABOUT OVER THE COUNTER (OTC) MEDICINE USE AMONG PREGNANT WOMEN IN THE ASIR REGION OF SAUDI ARABIA
Self-medication with OTC drugs is observed in many countries and deserves due concern as it may adversely affect maternal and fetal health. This practice may have an association with socio-demographic factors and knowledge about OTC medicine. A descriptive study was done using a questionnaire that collects information on socio-demographic status, prevalence and knowledge of OTC medicine use among ...
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ESTIMATION OF PHYTOCHEMICAL CONSTITUENTS IN THREE PLANTS WIDELY USED FOR TRADITIONAL TREATMENT OF ASTHMA IN MYANMAR
The crude drug powder extracts from three plants Datura metel L., (Solanaceae), Leucas cephalotes (Roth.). Spreng, Piper betel L., (Piperaceae) were screened for estimating phytochemical constituents. Phytochemical analysis of the extracts revealed that glycoside; tannin, saponin, carbohydrate and phenolic compounds are present in Piper and Leucas species. Besides glycoside, tannin, saponin, carbo...
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FORMULATION AND EVALUATION OF GASTRO RETENTIVE MUCOADHESIVE FILM OF RITONAVIR
Objective: The research work aims to formulate and evaluate the Gastro retentive mucoadhesive film of Ritonavir using polymers like HPMC K15M, Polyvinyl alcohol, and PEG 400 as a plasticizer by solvent casting method for treatment of AIDS. Method: Prepared gastro retentive mucoadhesive films were evaluated for various parameters such as in-vitro unfolding behavior of film, Folding endurance, Perce...
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BAEL (AEGLE MARMELOS) AN ASTONISHING HERB OF INDIA: A REVIEW
Aegle marmelos (L.) is an important plant with various medicinal values. It is commonly known as Bael (or Bel), belonging to the family Rutaceae. Bilwa is used to cure a variety of diseases. All the parts of this plant-like fruit, leaves, bark, stem and roots are used in different diseases, a variety of alkaloids are found in it. Compounds purified from the fruit have been proven to have biologica...
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IN-VITRO ANTI-BACTERIAL POTENCY AND PHYTOCHEMICAL ANALYSIS OF ANACARDIUM OCCIDENTALE L. LEAF AGAINST SOME GASTROINTESTINAL TRACT INFECTION-CAUSING BACTERIA
Bacterial infections are one of the prominent causes of health problems and mortalities around the world. Medicinal plants are a rich source of antimicrobial agents and provide a safer and cost-effective way of treating bacterial infections. The objective of the present investigation was to evaluate the anti-bacterial potential of petroleum ether and methanol extracts of Anacardium occidentale L. ...
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ANALYSIS OF PHYTOCHEMICAL CONSTITUENTS, ANTI-MICROBIAL ACTIVITY AND MOLECULAR CHARACTERIZATION OF MEDICINAL WEED SONCHUS OLERACEUS L. USING RAPD MARKER
In present study, Himalayan weed Sonchus oleraceus extracts are screened for the occurrence of bioactive compounds, anti-microbial activity, and its molecular characterization using RAPD. The agar well diffusion method was used to detect anti-microbial activity of aqueous, methanol, chloroform and ethyl acetate extracts of S. oleraceus. The anti-microbial activity of different extract was checked ...
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EXTENSIVE STUDY ON RETT SYNDROME: A CASE REPORT
Rett Syndrome is an extremely rare, post-natal, and serious genetic neurodevelopmental syndrome that occurs mostly in female children. It occurs due to the mutations in the MeCP2 gene of the X chromosome. Children with Rett syndrome are usually diagnosed within 24 months of their age. The mutation takes place on the S421 site of the MeCP2 gene. The information for coding MeCP2 protein is obtained ...
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PHYTOCHEMICAL EXPLORATION OF ANISOMELES MALABARICA R. BR. LEAVES BY SOLVENT EXTRACTION AND GC-MS
Medicinal plants belong to the Labiatae family, commonly known as the mint family. This family comprises the Anisomeles malabarica, which contain biologically important phytochemicals. Focus on solvent extraction of selected medicinal plant parts and its phytochemical analysis gives an insight for herbal drug discovery. A heat continuous percolation experiment was conducted for 24 hours using thre...
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PREPARATION AND EVALUATION OF EXTENDED-RELEASE MICROSPHERES OF QUETIAPINE FUMARATE
The objective of present study was to develop extended release microspheres of quetiapine fumarate using Eudragit RS 100 and Eudragit RL100 to reduce the dosing frequency. The quetiapine fumarate-loaded Eudragit microspheres were formulated by a solvent evaporation method. A 32 factorial design was employed to study the effect of concentration of sodium lauryl sulfate (SLS) and drug: polymer ratio...
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