Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
DEVELOPMENT OF RP-HPLC METHOD FOR SIMULTANEOUS EVALUATION OF UNIFORMITY OF DOSAGE UNITS FROM ASPIRIN AND DIPYRIDAMOLE EXTENDED-RELEASE CAPSULES
The aim of the present study is to develop a stability-indicating reverse-phase high-performance liquid chromatography method for the simultaneous estimation of Aspirin and Dipyridamole in combined extended-release dosage form 25/200mg, using a single unit of the capsule. Materials and Methods: Chromatographic separation was achieved with Agilent's high-performance liquid chromatography and X brid...
1328
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INVESTIGATION OF SOLVATION DYNAMICS AND HYDRATION PATTERN OF SIALIC ACID BY AB INITIO AND DFT METHOD
Sialic acid is the active site of neuraminidase virus and it proliferates the infection in the human body by cleaving it from the neuraminidase viral protein. The buried water molecule influences the binding between the ligand and the receptor. Hence, solvation dynamics and hydration pattern of sialic acid needs to be investigated to design the antiviral inhibitor. Cluster continuum solvation anal...
1313
635
STATISTICAL OPTIMIZATION OF ORALLY DISINTEGRATING TABLETS OF MEMANTINE HYDROCHLORIDE
Objective: The present work deals with the statistical optimization of memantine hydrochloride orally disintegrating tablets by the design of experimentation. The study was aimed at the development of a stable and robust formulation for the well-being of society for the treatment of Alzheimer’s disease, which is the most common form of dementia. Methods: Binder (X1), disintegrant (X2), and dilue...
1272
622
MOLECULAR DOCKING AND IN-SILICO ADME STUDIES OF NOVEL DERIVATIVE OF ERLOTINIB IN GLIOMA
Glioblastoma (GBM), with restricted therapy alternatives, is a catastrophic primary brain tumor. The receptor of the epidermal growth factor receptor (EGFR) in glioblastomas is recurrently enhanced, over articulated, or mutated, but up to 20 percent of GBM patients find it to be responded to kinase inhibition of EGFR. Several inhibitors of EGFR tyrosine kinase (TKI) failed clinically, due in part ...
2031
818
SCREENING MODELS OF LAXATIVE ACTIVITY
Substances that loose stools and boost bowel movements are laxatives, purgatives, or aperitives. They are used to treat constipation and to stop it. Constipation relates to infrequent or difficult to transfer bowel movements. Often the stool is hard and dry. Other symptoms may include abdominal pain, bloating, and feeling as if the bowel movement has not been fully passed. Hemorrhoid's anal fissur...
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AN OLD ADAGE MANAGEMENT PERSPECTIVE FOR DANDRUFF
Dandruff is a well-known and global consumer problem, characterized by flaking and scaling of the scalp, with itching and irritation. Although it is not a life-threatening disease, but it is directly related to individual self-esteem, confidence, and beauty. Approximately half of the population is suffering from dandruff and expending around billions of dollars, including hospital services and cou...
1576
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NANOPHYTOSOMES AN IMPERATIVE TECHNOLOGY FOR ENHANCING THE BIOAVAILABILITY OF BIOACTIVE CONSTITUENTS
Herbal medicine has been widely accepted as a promising approach for the treatment of various diseases with lower cost and minimized toxicity. Bioactive constituents isolated from the herbal source are equipped with synthetic drugs. The potency of any herbal medication is contingent on the delivery of the effectual level of the therapeutically active constituent. The integration of a novel drug de...
2097
913
RECENT FRONTIERS IN SELF MICRO EMULSIFYING DRUG DELIVERY SYSTEM: A REVIEW
Oral route has always been the preferred route of drug administration in many diseases. This route is limited to those drugs molecules that are permeable across the gastric mucosa and are sparingly soluble. Solubility is an important parameter to achieve the desired concentration of drug in systemic circulation for therapeutic response. As a consequence of modern drug discovery techniques, there h...
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1138
PROSTATE CANCER: RISK FACTORS, SCREENING, DIAGNOSIS AND TREATMENT
Prostate cancer is one of the most important cancer in men. In most cases, prostate cancer confirmed by histological and transrectal biopsy for the examination of prostatic tissue. Metastatic prostate cancer is second leading cause of death from cancer. Androgen deprivation therapy is common treatment in men with prostate cancer that may cause fatigue, increased body fatness, and loss of lean body...
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A REVIEW ON TRANSLATIONAL PERSPECTIVE AND EFFICACY OF DIFFERENT ENGINEERED THERAPEUTIC ANTIBODIES
From bench to bedside, clinical research had always played as a convenient tool in the field of cancer biology to inquire about the effectiveness of different anticancer drugs on different human-derived cancer cell lines. According to the American Cancer Society, nearly 4000 new cases and 1600 deaths predicted in 2019 in the United States. Besides, to these alarming statistics, rising cost and hea...
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