Most Cited
| Year | 2020 | 2021 | 2022 | Total |
|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 548 | 2053 |
| Citations | 699 | 263 | 21 | 983 |
| Projected Impact Factor | 3.76 | 2 | 0.64 |
PRODUCTION AND PURIFICATION STRATEGIES FOR LACCASE
Laccase belongs to polyphenol oxidases, which is a very wide family of copper-containing atoms in the center, which serves as the catalytic site. It is biochemically a glycoprotein with molecular mass being between 50kda to 130kda and 30% carbohydrate content, in addition to this it has three types of copper atoms. It is one of the most important enzymes due to its role in the food industry. It ac...
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NANOEMULSION: A PROMISING AND NOVEL NANOTHERAPEUTIC VEHICLE FOR TRANSDERMAL DRUG DELIVERY
Transdermal delivery of therapeutics has been identified by scientific researchers as an alternative choice of drug administration, owing to its unique and tremendous benefit over conventional and oral administrations, but its exploration has been limited because of the “skin barricade” as its major challenge. A special formulation that is capable of meeting up and overcoming its associated ch...
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MEDICINAL SIGNIFICANCE OF BENZIMIDAZOLE ANALOGUES: A REVIEW
Benzimidazoles are well known biologically active N-containing heterocycles, widely used as drugs such as antifungal, antibacterial, antiparasitic, and antihelmintic. In addition, N1 and C2-substituted benzimidazoles and their derivatives have been found to be potent biologically active compounds as well. Further, N1-substituted benzimidazoles have exhibited anti-microbial, antihelmintic activitie...
2087
730
ANTIPSORIATIC EFFECTS OF CLOBETASOL LOADED SOLID LIPID NANOPARTICLES ON IMIQUIMOD INDUCED PSORIASIS IN BALB/C MICE
The aim of the current investigation was to prepare and investigate the potential of Clobetasol (CP) loaded solid lipid nanoparticles based gel (SLN-gel) for the dermal delivery and to evaluate its anti-psoriatic efficacy by comparing with conventional ointment formulation. This study will provide an insight into the use of nanocarriers, esp. SLNs loaded with CP for the effective treatment of psor...
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PRELIMINARY PHYTOCHEMICAL SCREENING AND GC-MS ANALYSIS FOR IDENTIFICATION OF BIOACTIVE COMPOUNDS FROM ABUTILON FRUTICOSUM GUILL AND PERR. A RARE AND ENDEMIC PLANT OF INDIAN THAR DESERT
Present work was aimed to determine, identify, and characterize the bioactive chemical compounds from methanolic leaves extract of Abutilon fruticosum by GC-MS analysis. Fresh disease-free leaves were collected shade dried and powdered for extraction with HPLC grade methanol. Preliminary phytochemical screening of methanolic leaves extract was performed using standard methods to determine the pres...
2054
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IN-VIVO EFFECT OF WITHACOAGULIN AND COAGULIN C ISOLATED FROM WITHANIA COAGULANS DUNAL FRUITS ON BLOOD PRESSURE OF ALBINO RATS
The present study was designed to evaluate the in vivo effect of withacoagulin and coagulin C isolated from Withania coagulans Dunal fruits on blood pressure of albino rats. DOCA (10 mg/kg; i.p.) along with diet high in sodium chloride salt was used to induce hypertension in rats. Comparative effects of withacoagulin and coagulin C isolated from Withania coagulans Dunal fruits were observed. Femal...
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STRUCTURAL ELUCIDATION OF CHITOSAN BASED HETEROCYCLIC COMPOUNDS OF ANTI-MICROBIAL AND ANTI-CANCER ACTIVITY
Schiff bases from chitosan and 5-nitro salicylaldehyde-aniline complexes represented the important structural subject in excess of biologically active molecules, including synthetic. The introduction of 5-nitro salicylaldehyde at C-2 nitrogen position and aniline at C-6 oxygen position of chitosan. The structure-activity relationship (SAR) of the double Schiff based chitosan, synthesized from the ...
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FORMULATION AND EVALUATION OF FEBUXOSTAT FAST DISSOLVING TABLETS USING STERCULIA FOETIDA SEED STARCH AS EXCIPIENT BY LYOPHILIZATION TECHNIQUE
The present work is focused on the formulation of Febuxostat fast dissolving tablets by lyophilization technique using natural starch extracted from Sterculia foetida seeds. Starches were extracted using the alkali method, i.e., sodium hydroxide at 0.1%, 0.25%, and 0.5% concentrations and water from Sterculia foetida seed powder. These starches were evaluated for phytochemical and physicochemical ...
2048
865
DEVELOPMENT OF STABILITY INDICATING HIGH-PERFORMANCE THIN LAYER CHROMATOGRAPHIC METHOD FOR SIMULTANEOUS ESTIMATION OF TENELIGLIPTIN AND METFORMIN: APPLICATION TO ALKALINE DEGRADATION KINETIC STUDY
Stability indicating the HPTLC method was developed for simultaneous estimation of teneligliptin and metformin by using aluminum plates precoated with silica gel 60 F224 (Merck) and mobile phase toluene: methanol: GAA: TEA (5:4:0.5:0.5) with scanning wavelength of 257 nm. The developed method was validated for linearity, stability, accuracy, precision, robustness, LOD and LOQ as per ICH guidelines...
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DEVELOPMENT, CHARACTERIZATION AND EVALUATION OF NANOCRYSTALS OF NITROFURANTOIN
Nitrofurantoin is a broad-spectrum bactericidal antibiotic that affects both gram-negative and gram-positive bacteria. Nitrofurantoin exhibits bacteriostatic or bactericidal effects by inhibiting the synthesis of DNA, RNA, protein, and cell wall synthesis. Nanocrystals of NFT were prepared by a cold high-pressure homogenization technique. To improve the dissolution rate, the drug was formulated in...
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