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INCREASED ENZYMATIC ACTIVITY OF THYROID PEROXIDASE-TREATMENT FOR CONGENITAL HYPOTHYROIDISM
Congenital Hypothyroidism may be defined as a heterogeneous group of disorders characterized by goiter or cretinism due to an absolute or relative deficit of the enzyme Thyroid Peroxidase (TPO), and it is action. Chronic hypothyroidism also leads to goiter and cretinism associated with end gland damage, dysfunction, cancer, and failure, including the retina, kidney, nervous system, heart, and vasc...
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DEVELOPMENT AND IN-VITRO EVALUATION OF CENTELLA ASIATICA AND SILVER SOLUTION COATED SUTURES FOR ANTIBACTERIAL ACTIVITY
The research aim is to develop and evaluate Centella asiatica Chloroform extract and silver-coated suture against the most common organisms that cause surgical site infections (SSI) by in-vitro methods. This prospective study is to coat the Centella asiatica (CA) extract to the suture along with the silver nitrate solution. In this study, a suture filament was formulated with Poly Lactic Glycolic ...
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PHYSICO CHEMICAL AND ELEMENTAL ANALYS IS OF THE WHOLE PLANT POWDER OF AZOLLA MICROPHYLLA
Introduction: Anabaena azollae (AM) is used as a biofertilizer feed for cattle; much research is developing toward identifying the elements and their role in food supplements for human consumption. Objective: The study was to characterize the whole plant powder of the A. microphylla concerning physicochemical and elemental analysis. Material and Methods: The whole plant powder was subjected to phy...
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CLINICAL STUDY ON THE IMMUNOMODULATORY EFFECT OF NIDIGDHIKADILEHA ON PRANAVAHA SROTO DUSHTI W. S. R. UPPER RESPIRATORY TRACT INFECTIONS IN CHILDREN
Aim of study: A Randomized controlled trial was planned to evaluate the Clinical efficacy of Nidigdhikadileha an Ayurveda multi-dimensional herb preparation in children suffering from Recurrent Respiratory tract infection in children. Nidigdhikadileha contains Nidigdhika (Solanum Xanthocarpum), Pippali (Piper longum), Amrita (Tinospora cardifolia), and Nagar (Zingiber officinale). All these drugs ...
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CARBON NANOTUBES AS AN EFFECTIVE METHOD FOR ANTI-CANCER DRUG DELIVERY: A REVIEW
Cancer is a diverse category of diseases involving the growth of unchecked cells. Cancer cells uncontrollably divide and expand, creating malignant tumours that can invade surrounded parts of the body. Carbon nanotubes (CNTs) consist solely of a carbon atom organized into a tubular form in a sequence of condensed benzene rings. These sheets are rolled at a particular and distinct angle and the pro...
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GLUTATHIONE AND ANTIOXIDANT STUDY IN TESTES OF WISTAR RATS AFTER DIETARY COPPER DEFICIENCY
Copper is an essential trace element involved in a plethora of functions being a component of several enzymes. Copper deficiency affects people of all age groups, including infants, children, pregnant women, and men. Deficiency occurs due to numerous factors hindering the absorption/uptake of copper. Male Wistar rats (35-50 gm) were divided into four groups: Group 1: Negative control – fed with ...
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ENHANCEMENT OF THERAPEUTIC ACTION OF ANTI-HYPERLIPIDEMIC DRUGS BY USING A NOVEL NANOSUSPENSION-BASED APPROACH
Hyperlipidemia is an elevated condition of lipid levels in the body and is known to speed up a process of atherosclerosis that may prove fatal in the development of various cardiovascular diseases. The figures of the patient with hyperlipidemia are constantly increasing which is rising a serious risk factor for a group of cardiovascular diseases. Although various pharmacotherapy for hyperlipidemia...
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AN OVERVIEW OF THE DEVELOPMENT OF INSULIN DRUG DELIVERY BY POLYMERIC NANOPARTICLES
Anti-diabetic medications, like insulin and glucagon-like peptide1(GLP-1) and its analogues are critical for diabetics to maintain blood glucose control. The difficulty of current insulin-based therapies for Type I & II diabetes mellitus, as well as the risks connected with fluctuations in blood glucose levels (hyperglycemia and hypoglycemia), served as the impetus for the establishment of "s...
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COMPARATIVE ANALYSIS OF PHYSICO-CHEMICAL PROPERTIES OF SOIL OF VIZAG NEAR BHEEMILI RIVER (ESTUARINE), WATER OF ANTARVEDI ANDHRAPRADESH STATE
Environmental changes influence Physical and Chemical reactions such as pH, Temperature, EC and chemical properties such as Dissolved Oxygen, Organic matter, Silica provide important information on Soil and Water quality different sources of variations and their effects on activities and biodiversity of Soil and Water. In the present study, the Physico-Chemical parameters of Soil sample from Vizag...
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CONVENTIONAL AND NON-CONVENTIONAL TECHNIQUES FOR EXTRACTION OF FLAVONOIDS FROM SELECTED PLANTS
Medicinal plants are enriched with biological substances that are proven to be a direct or indirect source of modern drugs. The relevance of the exploration of new natural reservoirs of pharmaceutical potential has increased immensely after COVID-19. The present study deals with the extraction of flavonoids from selected plants i.e. Ricinus communis, Euphorbia hirta and Croton bonplandinum from ...
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