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ANTIMICROBIAL AND ANTI-INFLAMMATORY POTENTIAL OF THE LEAF EXTRACTS, COLUMN FRACTIONS AND COMPOUNDS OF THE MEDICINAL PLANT JASMINUM FLEXILE VAHL
The medicinal plant Jasminum flexile is reported in traditional medicine as an antidiabetic and anti-inflammatory agent. There is no scientific report on the antibacterial and anti-inflammatory activity of extracts of Jasminum flexile. This study investigated the antibacterial and anti-inflammatory potential of the hydroethanol extract of leaves of Jasminum flexile, its column fractions and consti...
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EFFECT OF CUSTOMIZED DASH DIET AND LIFESTYLE MODIFICATION ON BLOOD PRESSURE AMONG STAGE-1 HYPERTENSIVE INDIVIDUALS
This study aims to evaluate the impact of a personalized DASH diet and lifestyle modifications on blood pressure levels in individuals diagnosed with stage-1 hypertension. An observational study with purposive sampling was carried out over one-year duration, specifically from April 2022 to March 2023. Data was gathered through a self-structured interview schedule questionnaire and subjected to des...
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COMPARISON OF SARS CoV-2 RT-PCR TEST WITH RAPID ANTIGEN DETECTION KIT AND OTHER NON SPECIFIC TEST
Background: Severe Acute Respiratory Syndrome Corona Virus Disease 2019 (COVID-19) is responsible for the COVID-19 pandemic causing respiratory illness worldwide. Hence there is an urgent need for simple, rapid, and accurate tests for diagnosis. Performance characteristic of Rapid Antigen detection test for identifying sensitivity and specificity with gold standard Real-Time Polymerase Chain React...
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EVALUATION OF ANTILIPIDEMIC POTENTIALS OF PHASEOLUS VULGARIS ON ALLOXAN-INDUCED DIABETIC RATS
Healthy diet has been known to play a key role in managing and preventing diseases. The health benefits of consuming common beans (Phaseolus vulgaris) are widely acknowledged and are ascribed mostly to their high dietary fiber contents and polyphenols. Various animal experimental studies have shown that polyphenol in common beans has antioxidant properties and other biological activities. This stu...
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DE RITIS RATIO OF COVID-19 PATIENTS ADMITTED DURING FIRST, SECOND AND THIRD WAVE
Background: To date, the 2019 novel coronavirus pneumonia (COVID-19) is the greatest public medical issue in the world. World Health Organization (WHO) declared this outbreak a “public health emergency of international concern” on January 31, 2020. Therefore, it bodes well to look for a potential biomarker that could quickly and effectively distinguish serious cases early. Of the total confirm...
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MACHINE LEARNING STRATEGIES FOR DRUG DISCOVERY AND DEVELOPMENT
This review paper provides a comprehensive overview of the role of machine learning (ML) in drug discovery and development within the pharmaceutical industry. It begins by outlining the foundational concepts of machine learning, highlighting its ability to enhance decision-making and improve accuracy through data analysis. The paper emphasizes the growing adoption of ML techniques across the pharm...
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STUDY ON REMOVAL EFFICIENCY OF DIFFERENT MICROORGANISMS IN ANTIBIOTIC-PRODUCING PHARMACEUTICAL INDUSTRIES WASTEWATER
Antibiotic yield has been raised by numerous pharmaceutical firms in response to the rising population, the COVID-19 outbreak, and the introduction of several new diseases. Several heavy metals are used in the antibiotics' formulation. The release of antibiotics and heavy metal ions has wreaked havoc on the ecosystem. The issue with heavy metals is that the bulk of them last a long time in the env...
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DEVELOPMENT OF VALIDATED HPTLC METHOD FOR SIMULTANEOUS ESTIMATION OF FERULIC ACID AND ELLAGIC ACID
A simple, precise, accurate and rapid high performance thin layer chromatographic method has been developed and completely validated for the estimation of ellagic acid and ferulic acid in herbal formulation. Quantification was carried out with pre-coated silica gel aluminium plate G60F254 (10x10cm) as stationary phase, mobile phase consisting of Ethyl acetate: toluene: formic acid: methanol (3.5:...
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CHRONOTHERAPY THROUGH REGULATION OF CIRCADIAN RHYTHMS- AN OVERVIEW
The objective of chronotherapy is to optimize medical treatments taking into account the body's circadian rhythms. Drug delivery systems that precisely control the release rates or target drugs to a specific site have an enormous impact on the health care system. Over the past few years, pharmaceutical industry has focused its research in the development of various Chrono therapeutic delivery s...
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A SYSTEMATIC REVIEW ON EMULGEL
A topical drug delivery system involves applying medication to the skin for therapeutic effects or to treat skin disorders. Traditional gels often struggle to deliver hydrophobic drugs effectively, a challenge that can be overcome with emulgels. Emulgels, which combine emulsions and gels, create a dual-release control system that enhances medication efficacy. This innovation is essential in topica...
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