ETHNOMEDICINAL USE OF PTERIDOPHYTES IN REPRODUCTIVE HEALTH OF TRIBAL WOMEN OF PACHMARHI BIOSPHERE RESERVE, MADHYA PRADESH, INDIA
This paper describes the utilization of pteridophytes for the treatment of various gynecological and other related problems by the indigenous women of Pachmarhi Biosphere Reserve in Madhya Pradesh. The present study reveals that 23 species of pteridophytes belonging to 15 families and 18 genera are traditionally used by tribal women of Korku, Gond, Bharia, Bhil, Mauria, Maria, Paria, Bhatara and B...
The present research work was aimed at the enhancement of solubility of Candesartan by Self Emulsifying Drug Delivery Systems (SEDDS). Candesartan is a BCS class II drug having low aqueous solubility and high permeability; hence its bioavailability is solubility rate limited. The saturated solubility of Candesartan in various oils and surfactants was determined. The excipients were screened and se...
ASSESSMENT OF DRUG USE PRACTICES AND COMPLETENESS OF PRESCRIPTIONS IN GONDAR UNIVERSITY TEACHING REFERRAL HOSPITAL
Background: Rational drug use is a tool through which safe, effective and economic medication is provided. Rational prescribing ensures adherence to treatment and protects drug consumers from unnecessary adverse drug reactions. Rational dispensing on the other hand, promotes the safe, effective and economic use of drugs. Objectives: The aim of this study was to assess drug use practices and com...
DEVELOPMENT OF A SELF MICRO-EMULSIFYING TABLET OF CYCLOSPORINE- A BY THE LIQUISOLID COMPACT TECHNIQUE
Purpose: The aim of this study was to enhance the dissolution rate of Cyclosporine A, a poorly water-soluble drug by developing a self micro-emulsifying (SME) tablet formulation by using the liquisolid compact technique. A liquisolid system is formed by converting a liquid formulation into a dry, free-flowing and compressible powder mixture with selected carrier material and coating material. This...
The ophthalmic in-situ gels now days proved an palpable sustained drug delivery in various eye diseases. The formulation of in-situ gels for eye which carries the advantages like easy for administration, reduces frequency of dose and improves patient compliance. The formation of in-situ gels depends on phase transition system or sol-gel transition system. The formulation approaches like temperatur...
The ethanolic extract of bark of Dalbergia sissoo Roxb. was investigated for its activity against Indian earthworms Pheretima posthuma and nematode Ascardi galli. Various concentrations (10, 20, 50 mg/ml) of ethanolic extract were tested, which involved determination of time of paralysis and time of death of the worms. It was compared with Piperazine citrate (15 mg/ml) and Albendazole (20 mg/ml) a...
Cardiovascular disease remains a leading cause of death in most industrialized countries. Therefore, finding ways to reduce the mortality of cardiovascular disease remains an important public health goal. This review deals with medicinal plants possessing cardioprotective and cardiotonic activity. This review work explains chemical and pharmacological status of various cardioprotective plants incl...
Thespesia populnea is a reputed ever green tree belonging to the family malvaceae; commonly known as Indian tulip tree. The plant is distributed tropical regions and coastal forest in India. It is well known and all the parts are used in traditional system of medicine. The plant has been used as astringent, antibacterial, hepatoprotective, haemostatic, anti-diarroheal and anti-inflammatory. The sh...
Vitamin A is an essential vitamin which is required in the vision process, epithelial maintenance, mucous secretion and reproduction obtained from carotenoids. Carotenoids have been considered to provide benefits in age-related diseases, against some forms of cancer (in especial lung cancer), strokes, macular degeneration, and cataracts. Till date, more than 600 carotenoids are known and 50 of t...
HPTLC METHOD FOR SIMULTANEOUS DETERMINATION OF NAPROXEN SODIUM AND SUMATRIPTAN SUCCINATE IN PHARMACEUTICAL DOSAGE FORM
A rapid and simple high performance thin layer chromatography (HPTLC) method with densitometry at 230 nm was developed and validated for simultaneous determination of Naproxen sodium and Sumatriptan succinate from pharmaceutical preparation. Separation was performed on aluminum-backed silica gel 60F254 HPTLC plates as stationary phase and using a mobile phase comprising of methanol:distilled water...