Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
SYNTHESIS AND BIOLOGICAL ASSESMENT OF QUINAZOLONE BASED AMIDE LINKAGE CONTAINING THIAZOLIDINONE AND THEIR DERIVATIVES
A number of substituted quinazolones are well known for their pharmacological activities like anti-inflammatory, antibacterial and analgesic etc. The present work deals with synthesis of quinazolone based thiazolidinone in order to enhance the biological properties. A Series of (2-(substituted phenyl)-4-oxothiazolidin-3-yl) -4- (4-oxo-2-phenyl quinazolin-3(4H)-yl) benzamide (6a-6h) were synthesi...
3672
1536
SPREADING OUT OF ACECLOFENAC SUSTAINED RELEASE MICROCAPSULES BASED ON HPMC 50 CPS BY EMULSION SOLVENT EVAPORATION TECHNIQUE
Sustained released Aceclofenac microcapsules based on synthetic hydrophilic polymer hydroxypropyl methylcellulose (HPMC) were developed in this study in an attempt to design a dosage form that would manifest desirable release profile. W/O emulsion solvent evaporation technique was employed. Various release retarding agents were used to provide the analgesic and anti-inflammatory action of aceclof...
3872
1721
PRECLINICAL EFFICACY AND SAFETY OF HERBAL FORMULATION FOR MANAGEMENT OF WOUNDS
Background: Medicinal plants in Tripathi hills and other developing countries have been scientifically demonstrated to have medicinal benefits but few or none have been translated to products for clinical use. Most herbal products developed by local herbalist and sold to the public are not standardized and lack efficacy and safety data to support use. Objective: to evaluate the medicinal plants...
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1538
ROLE OF ACUTE PHASE PROTEINS STATUS IN CHRONIC ALCOHOLIC LIVER DISEASES
Back ground: Alcoholic cirrhosis is a condition of irreversible liver disease due to the chronic inflammatory and toxic effects of ethanol on the liver. Acute alcoholic hepatitis occurs in habitual drinkers, often a period of increased alcohol intake. Although, the clinical features may mimic acute viral hepatitis. Progression of liver fibrosis to cirrhosis is dangerous as well as potentially life...
3809
1556
AMPLIFICATION AND SEQUENCING OF MITOCHONDRIAL DNA (HVR-I) EXTRACTED FROM 1200 YEARS OLD HUMAN BONE SPECIMEN
Ancient DNA help in better understanding the evolution and migration pattern of humans throughout the world. The present work is a preliminary effort, to extract and amplify the ancient DNA from human bone samples provided by the Anthropological survey of India collected from the Himalayan region in 1952. Many technical difficulties arise during DNA extraction, PCR amplification and sequencing w...
4252
1443
QUALITY ASSESSMENT OF UNANI POLYHERBAL FORMULATION “HABB-E-AZARAQI” BY CONTEMPORARY SCIENTIFIC PARAMETERS
Demand of the Unani herbal drugs is becoming universal as the people are becoming more and more cognisant about the natural benefits of medicines with plant origin. Herbal drugs being easily affordable are becoming the first preference for the common man over purchasing the expensive modern pharmaceuticals. The WHO estimates that 80% of the world population rely on the medicines of plant origin fo...
6707
2229
LIQUID CHROMATOGRAPHIC SEPARATION AND ANALYSIS OF TELMISARTAN AND HYDROCHLOROTHIAZIDE IN PHARMACEUTICAL FORMULATIONS
An accurate, simple and precise RP-HPLC method for the simultaneous determination of telmisartan and hydrochlorothiazide in pharmaceutical formulations was developed and validated. Chromatographic separation of two drugs was achieved on a Kromasil C18, (250x4.6nm, 5µm) column by using the mobile phase consisted of methanol, tetrahydrofuran and water in the ratio 55:05:40 at a flow rate of 1mL/min...
4169
1659
INCIDENCE AND COMPARATIVE ANALYSIS OF ADVERSE DRUG REACTIONS IN DOTS
To assess the adverse drug reactions (ADRs) induced by antitubercular drugs used in Directly Observed Treatment Short Course (DOTS) from previously reported 8 articles from referred sources. Articles related to adverse drug reactions induced by first line anti- tuberculosis drugs in DOTS therapy published during 2002 to 2012 were searched. The incidence rate of each type of ADR from entire ADRs we...
3848
1456
HERB-DRUG INTERACTION: AN OVERVIEW
Plants have always provided an important source of medicines. They may be used by natives in folk medicine and later adopted by conventional western medicine as their efficacy was confirmed. Any pharmacological modification caused by herbal substances to another prescription medication (diagnostic, therapeutic or other action of a drug) in or on the body. An herb might increases or decreases the e...
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4679
CHITOSAN-BASED INTRATUMORAL INJECTABLE NANOPARTICLES FOR GENE DELIVERY TO PANCREATIC CANCER CELLS
One of the obstacles to effective intratumoral gene delivery lies in low transfection efficiency of non-viral vectors. Thus, in this study we evaluate the application of Diethyl methyl chitosan (DEMC) in intratumoral gene delivery of pancreatic cancer. DEMC/ pEGFP nanoparticles are prepared by polyelectrolyte complexation. After nanoparticle characterization via atomic force microscopy (AFM), in i...
3669
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