BIOGENIC SYNTHESIS OF MYCONANOPARTICLES FROM MUSHROOM EXTRACTS AND ITS MEDICAL APPLICATIONS: A REVIEW
Mushroom extracts such as proteins, amino acids, polysaccharides and vitamins implicated as the reducing, stabilizing and capping agents in synthesis of myconanoparticles. Therefore, it is just a little attempt to study the journalism of this important of myconanoparticle. For this literature survey, basically library data was collected and digital resources were also included. From these sources ...
Kinetics and stoichiometry S-oxidation reaction of sodium monohydrate Mezlocillin (Mezl) using potassium hydrogen peroxomonosulfate in aqueous solutions using iodometric titration were studied. Baypen®-powder Mezl sodium monohydrate in flacons for preparation of solution for injections (Mezl 1.0 g). A new iodometric method for the quantitative determination of sodium monohydrate Mezl in Baypen® ...
Neonatal sepsis is one of the commonest cause of neonatal mortality in the developing world which can be classified into early onset sepsis (EOS) which occurs in the first 7 days of life and late onset sepsis (LOS) which occurs ≥7 days of life. E. coli has been reported to be one of the significant and most common nosocomial pathogen which may cause septicemia, pneumonia and meningitis in the ne...
MEASUREMENT OF pH OF THE DIGESTIVE VACUOLE ISOLATED FROM THE PLASMODIUM FALCIPARUM-INFECTED ERYTHROCYTE BY DIGITONIN PERMEABILIZATION
The acidic pH of the digestive vacuole (DV) of P. falciparum is thought to play a major role in the mechanisms of digestion of host erythrocyte hemoglobin, detoxification of heme, and chloroquine (CQ) action and resistance. However, a definitive measurement of the DV pH has been technically difficult. A previous study by Abu Bakar (2015) measured the DV pH by using fluorescein isothiocyanate-dextr...
CONVOLUTION STUDY AND THE ALCOHOLIC BEVERAGE EFFECT ON LANSOPRAZOLE DELAYED-RELEASE CAPSULES AND APPLICATION OF SIMILARITY FACTOR TO TWO-STAGE IN – VITRO DISSOLUTION PARADIGM
Lansoprazole, a proton pump inhibitor, is used to treat ulcers in the stomach and duodenum. In order to protect this acid labile drug from being degraded in the gastric medium, the marketed oral dosage forms are formulated into delayed release pellets and tablets. The aims of this research were (1) to investigate the principal site of drug release and absorption rate between an over-the-counter (O...
SYNTHESIS NEW MOLECULARLY IMPRINTED POLYMERS FOR THE SELECTIVE ELECTRODES OF ISOPROPAMIDE FROM PHARMACEUTICAL SAMPLES
Liquid electrodes of polymers imprinted with Isopropamide (ISP) were synthesized based on precipitation polymerization mechanism. The molecularly imprinted polymer (MIP) and non-imprinted polymers (NIP) were synthesized using (ISP) as a template. In the polymerization process, 2-Hydroxyethyl meth acrylate (2-HEMA) and 2-Vinyl pyridine (2-VP) were used as monomers. Di-vinylbanzene (DVB) was used as...
In the present work, we have measured natural radioactivity in twelve building materials samples for four kinds (Brick, cement, gypsum and sand) obtained from some Iraqi governorates by using High Purity Germanium (HPGe) radiation detectors system. The results of measurements have shown that the average values specific activity concentrations for 238U, 232Th and 40K which were equal to (24.236 ± ...
Nanoparticles have advantages, such as small size, high surface area, and modification using functional groups for high capacity or selectivity. Nanoparticles with Proteins are especially worthy of notice because they can be used for site specific targeting. Particulate systems like nanoparticles have been used as a physical approach to alter and improve the pharmacokinetic and pharmaco-dynamic pr...
THREE-DIMENSIONAL QUANTITATIVE STRUCTURE ACTIVITY RELATIONSHIP STUDIES ON DIVERSE STRUCTURAL CLASSES OF NATURAL FLAVONOIDS AS AMV AND HIV REVERSE TRANSCRIPTASE INHIBITORS USING CoMFA AND CoMSIA
In this study, comparative molecular ﬁeld analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) were performed on a series of 73 experimentally reported natural flavonoid derivatives as AMV and HIV Reverse transcriptase (RT) inhibitors with pIC50 values ranging from 4.00 to 5.92. Based on alignment, highly predictive CoMFA and CoMSIA were obtained with cross-validated q...
The NSAIDs are popular in reducing acute and chronic inflammation as they have no abuse liability. QSAR (Quantitative structure-activity relationship) approach is a very useful and widespread technique for drug design. 2D QSAR models are based on descriptors derived from a two-dimensional graph representation of a molecule. The 2D QSAR study was performed on selected twenty-four compounds from syn...