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QUALITY EVALUATION OF PARACETAMOL TABLETS OBTAINED FROM THE COMMON SHOPS (KIOSKS) IN ADDIS ABABA, ETHIOPIA
The effectiveness of drugs is directly related to the quality thus quality evaluations of medications throughout the production process and distribution are very essential. Counterfeit medications are known to have poor quality as the medications are in the market without the consent of the regulatory body. A total of 11 samples of paracetamol tablets were collected from kiosks, one from each sub ...
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A REVIEW ON THE ROLE OF PHARMACOGENOMICS IN DRUG DISCOVERY AND DEVELOPMENT
Pharmacogenomics (constitute both branch i.e pharmacology and genetic) is the study of the role of genetics in drug response. It deals with the effect of genetic variation on drug response in patient by correlating the gene expression with the pharmacokinetic parameter i.e absorption, distribution metabolism and excreation. The Pharmacogenomics is used in the research to increase the safety and ef...
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β-LACTAMS: A MINI REVIEW OF THEIR BIOLOGICAL ACTIVITY
Synthesis of heterocylic compound has always drawn the attention of chemist over the years mainly because of their important biological properties. Particularly, the role of β–lactam which are endowed with unique structure and potent biological activity. The β-lactam heterocycles are considered as an important contribution of science to humanity since they have been constituents of living orga...
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A STUDY ON DIHYDROFOLATE REDUCTASE AND ITS INHIBITORS: A REVIEW
Dihydrofolate reductase (DHFR) was discovered in the late 1950s by investigators searching for folate-dependent enzymes involved in 1-carbon metabolism, with its already known application as anti-cancer and as antibiotics. This study focuses on structure of Dihydrofolate, its interaction with specific amino acids, mechanism of DHFR catalysis. The reason of study was to focus on compounds which can...
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ISOLATION, IDENTIFICATION AND CHARACTERIZATION OF HEAVY METAL RESISTANT BACTERIA FROM SOIL OF AN IRON INDUSTRY, HARYANA (INDIA).
Metallic contaminants in the soil are hazardous and their accumulation in plants and water may be dangerous. Microorganisms have properties to adsorb, absorb and accumulate heavy metals. Moreover, they play the role of problem solver by resolving key problems associated with different kinds of metals. The study was undertaken to isolate and identify heavy metal resistant bacteria in soil around ir...
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EVALUATION OF ANTIMICROBIAL AND ANTIFUNGAL PROPERTY OF DHOOPANA KARMA (FUMIGATION) – BY “DHUP”AN AYURVEDIC DHOOPANA PRODUCT
There are millions of micro-organisms around us, amongst 20-25% are non pathogenic. Pathogenic microbes present in the environment around us are responsible for various health related problems. Reducing microbial load to non-pathogenic levels may be the purpose of traditional fumigation techniques like Dhoopana, Homa, and Havana etc. This is also evident from Ayurvedic literature wherein fumigat...
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BIOPHYTUM SENSITIVUM DC.: A REVIEW
Biophytum sensitivum DC. (Family - Oxalidaceae), commonly known as “Lajjalu” in Northern India, is an annual herb that grows at the foothills of the Himalayas. It is an indigenous medicine, used against “Madhumeha” (Diabetes mellitus) apart from being used as tonic, stimulant, and in the treatment of stomach ache, asthma, insomnia, convulsions, cramps, chest-complaints, inflammations, tumo...
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DALBERGIA SISSOO LINN. AN OVERVIEW MORPHOLOGY, PHYTOCHEMISTRY AND PHARMACOLOGY
The present review is, therefore, an effort to give a detailed survey of the literature on its pharamacognosy, phytochemistry, traditional uses and pharmacological studies of the plant Dalbergia sissoo. The genus consists of 300 species among which 25 species occur in India. The generic name Dalbergia honors the Swedish brothers Nils and Carl Dalberg, who lived in the 18th century. Dalbergia sis...
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EXPLORING WOMEN’S AWARENESS ABOUT BREASTFEEDING AND HEALTH BENEFITS USING A CROSS-SECTIONAL SURVEY IN DHAKA CITY, BANGLADESH
This cross-sectional questionnaire based study was conducted among 200 randomly selected child bearing mothers aged 16 to 40 to evaluate their awareness regarding breastfeeding and its health benefits in urban and slum area of Dhaka city from July to December 2013. The study showed that about 46% of respondents completed higher secondary education or more and about 27% were illiterate. A significa...
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A COMPREHENSIVE REVIEW: BERGENIA LIGULATA WALL – A CONTROVERSIAL CLINICAL CANDIDATE
Bergenia ligulata Wall is considered amongst the high valued medicinal herbs and one of the important examples of controversial drugs which is popularly known as ‘Paashanbheda’ (meaning ‘to dissolve the stone’) in Indian systems of medicine. The phytochemical studies have shown the presence of many secondary metabolites belonging to coumarins, flavonoids, benzenoids, lactone, carbohydrate,...
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