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METHOD DEVELOPMENT AND VALIDATION OF FOLIC ACID BY UV-VISIBLE SPECTROSCOPY
The present study a simple, accurate, precise and cost effective UV-Visible spectrophotometric method for development and validation of folic acid as vitamin. folic acid is a water soluble vitamin, so solvent used throughout the experiment was chloroform, butanol,0.1N NaoH, water .the absorption maxima of drug was found at 250nm . Beer’s law was obeyed in the range of 5ppm-30ppm. The developed...
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3298
FORMULATION AND EVALUATION OF IMMEDIATE RELEASE TABLET OF VALSARTAN
The immediate release tablet of antihypertensive drug Valsartan were prepared and evaluated to increase solubility and bioavailability of low soluble drug. The tablets were prepared by direct compression method using Surfactants such as Poloxamer 188, Sodium stearate, Sodium Lauryl Sulfate and Superdisintegrant such as Cross carmellose sodium were used in tablet formulation. The formulation were e...
10166
3135
A REVIEW: ROLE OF DOXORUBICIN IN TREATMENT OF CANCER
Cancer is a very complex genetic disorder that is mainly caused by carcinogens. Carcinogens can be present in the air, water, food, chemicals, and sunlight that are exposed to the people. In the case of leukemia, the body produces large numbers of abnormal white blood cells. In the study of blood cancer that is leukemia, blood disorders through visual inspection of microscopic images of blood cell...
10157
2403
A COMPREHENSIVE REVIEW: BERGENIA LIGULATA WALL – A CONTROVERSIAL CLINICAL CANDIDATE
Bergenia ligulata Wall is considered amongst the high valued medicinal herbs and one of the important examples of controversial drugs which is popularly known as ‘Paashanbheda’ (meaning ‘to dissolve the stone’) in Indian systems of medicine. The phytochemical studies have shown the presence of many secondary metabolites belonging to coumarins, flavonoids, benzenoids, lactone, carbohydrate,...
10157
7291
OPTIMIZATION OF TELMISARTAN TABLET FORMULATION BY 23 FACTORIAL DESIGN EMPLOYING βCD, PRIMOJEL AND TWEEN 80
The objective of the present study is optimization of telmisartan tablet formulation employing βCD, Primojel, and Tween 80 by 23 factorial design to achieve NLT 85% dissolution in 10 min. Eight telmisartan tablet formulations were prepared using selected combinations of the three factors as per 23 factorial design. Telmisartan tablets were prepared by direct compression method and were evaluated....
10140
1336
BOSWELLIA SERRATA ROXB. A TRADITIONAL HERB WITH VERSATILE PHARMACOLOGICAL ACTIVITY: A REVIEW
Boswellia serrata Roxb. is known as kundur in Unani medicine, belongs to the family Burseraceae. The plant is widely distributed in India, it occurs in dry hilly forests of Rajasthan, Madhya Pradesh, Gujarat, Bihar, Assam, Orrisa, central peninsular regions of Andhra Pradesh etc. In ancient times Hindus, Babylonians, Persians, Romans, Chinese, Greeks and the people of old American civilization use...
10111
3546
FORMULATION DEVELOPMENT AND SOLUBILITY ENHANCEMENT OF ROSUVASTATIN CALCIUM TABLET PREPARED BY COMPLEXATION WITH β-CYCLODEXTRIN BY KNEADING METHOD
Rosuvastatin is a Dyslipidaemic agent, which acts by inhibiting HMG-CoA reductase enzyme and used in the treatment of hyperlipidemia. But Rosuvastatin calcium (RST) exhibit unsatisfactory dissolution profiles, problems of absorption and poor bioavailability. Thus objective of the study is to increase the solubility and dissolution rate of Rosuvastatin calcium (RST), a poorly water-soluble 3-hydrox...
10100
1993
A REVIEW ON UNANI TRADITIONAL USES OF SAMBHALU IN FEMALES AS WELL AS PHYTOCHEMICAL AND PHARMACOLOGICAL PROPERTIES
Herbal medicine, rather than merely curing a particular disease, aims at returning the body back to its natural state of health. Vitex negundo Linn. known as Sambhalu in Unani medicine belongs to family Verbenaceae. It is a large aromatic shrub distributed throughout India. It has been used since ancient times as a female remedy in Unani medicine. It is a well known plant because of its two main p...
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3486
ANTIMICROBIAL ACTIVITY OF COCONUT SHELL OIL
Coconut shell oil was extracted from raw coconut shells, collected from Thiruvallur District. These were extracted using various solvents based on the polarity which includes ethanol, chloroform, acetone, petroleum ether and aqueous. The antibacterial activity against the growth of Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa and Salm...
10054
1956
FORMULATION AND EVALUATION OF NAPROXEN AND PANTOPRAZOLE MULTILAYERED TABLETS
Naproxen, a non-steroidal anti-inflammatory drug suggested for the long term treatment of disease conditions such as Rheumatoid Arthritis and Osteoarthritis poses an immediate risk of stomach ulceration. To avoid this risk, a proton pump inhibitor is often prescribed along with it. In the present study, Naproxen (500mg) is prepared in combination with Pantoprazole, a proton pump inhibitor as a mul...
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2535