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METHOD DEVELOPMENT AND VALIDATION OF RP-HPLC METHOD FOR THE ESTIMATION OF EMPAGLIFLOZIN IN API
An accurate, precise and rapid RP-HPLC method was developed and subsequently validated for the determination of Empagliflozin in API. Better separation of the drug was achieved on Intersil column(150x40mm, 5 μm) with the mobile phase consisted of mixture of 0.01 M acetate buffer, methanol in ratio of (30:70v/v ) at flow rate of 2ml/min, with detection at 260nm using PDA detector. The retention...
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EFFECTIVENESS OF AMLA, JAGGERY AND PUMPKIN LEAVES EXTRACT ON THE LEVEL OF HAEMOGLOBIN, VITAMIN C AND IRON AMONG ADOLESCENT GIRLS WITH IRON DEFICIENCY ANEMIA
Background: Iron deficiency anaemia poses a burden on the limited health care delivery system. Current pharmacological anti anaemic agents cause undesirable side effect like nausea, vomiting dark stool etc. Herbal remedies offer the potential for alternative treatment strategies. This study was therefore conducted in an effort to formulate a food based extract prepared from plants products. Object...
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A REVIEW ON UNANI TRADITIONAL USES OF SAMBHALU IN FEMALES AS WELL AS PHYTOCHEMICAL AND PHARMACOLOGICAL PROPERTIES
Herbal medicine, rather than merely curing a particular disease, aims at returning the body back to its natural state of health. Vitex negundo Linn. known as Sambhalu in Unani medicine belongs to family Verbenaceae. It is a large aromatic shrub distributed throughout India. It has been used since ancient times as a female remedy in Unani medicine. It is a well known plant because of its two main p...
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EVALUATION OF ANXIOLYTIC ACTIVITY OF HOMEOPATHIC REMEDY ARGENTUM NITRICUM OF 30 C POTENCY AFTER CHRONIC ADMINISTRATION IN RODENTS
Anxiety affects a large number of the population that creates an economic burden. Various traditional medicines like barbiturates, benzodiazepines and SSRI’s are used as anxiolytics but due to their potential to produce adverse effect on cognition limits their chronic use. Several homeopathic remedies are used for treating anxiety. For the first time this study was designed to determine anxiol...
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FORMULATION AND EVALUATION OF NAPROXEN AND PANTOPRAZOLE MULTILAYERED TABLETS
Naproxen, a non-steroidal anti-inflammatory drug suggested for the long term treatment of disease conditions such as Rheumatoid Arthritis and Osteoarthritis poses an immediate risk of stomach ulceration. To avoid this risk, a proton pump inhibitor is often prescribed along with it. In the present study, Naproxen (500mg) is prepared in combination with Pantoprazole, a proton pump inhibitor as a mul...
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CHEMICAL COMPOSITION AND ANTI-INFLAMMATORY ACTIVITY OF ESSENTIAL OILS FROM THE LEAVES OF OCIMUM BASILICUM L. AND OCIMUM GRATISSIMUM L. (LAMIACEAE)
Ocimum basilicum L. and Ocimum gratissimum L. (Lamiaceae) are widely distributed aromatic herbs used in ethnomedicinal management of a range of inflammatory disorders. In the present work we evaluated the topical anti-inflammatory effects of the volatile constituents extracted from the fresh leaves of these plant species. Fresh leaves of the plants were subjected to hydro distillation to obtain th...
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AYURVEDIC ASPECT OF BACTERIA AND BACTERIAL FOOD POISONING
Bacterial Food Poisoning' is a common name given to predominantly gastro-intestinal infections which arise after the consumption of food or drink that is contaminated with disease-causing bacteria. Over 250 organisms are known to cause food borne illnesses. Ayurveda is an ancient medical science & has described the food poisoning indirectly in the form of Anna Vishaktata. The aims of present s...
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TINOSPORA CORDIFOLIA: ETHNOBOTANY, PHYTOPHARMACOLOGY AND PHYTOCHEMISTRY ASPECTS
Tinospora cordifolia (Thunb.) Miers, (Guduchi) is an evergreen perennial climber. This deciduous and dioecious plant belongs to the family Menispermaceae. It is a plant of significant medicinal importance in the Indian system and designated as Rasayana. Its efficacy has been also recognized by the modern system of medicine. The whole plant is used medicinally however; the stem is approved for us...
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ANTIEMETICS: A REVIEW
The act of emesis is controlled by the vomiting centre in the medulla, which integrates afferent input from the vestibular system, the chemoreceptor trigger zone (CTZ), the cortex and the gut. Nausea and vomiting induced by several cancer chemotherapy agents is often the most distressing side effect of treatment. The mechanism of action of antiemetic is related to blockage of various type of recep...
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CORIANDRUM SATIVUM- REVIEW OF ADVANCES IN PHYTOPHARMACOLOGY
Coriandrum Sativum family Umbelliferae is highly reputed ayurvedic medicinal tree commonly known as the Dhanya. It is a glabrous, aromatic, herbaceous annual plant, small sized tree growing throughout India, Italy, Netherlands, Central and Eastern Europe, China and Bangladesh. Essential oil, flavonoids, fatty acids, and sterols have been isolated from different parts of C. sativum. The different p...
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