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A REVIEW ON SUBLINGUAL SPRAY: NOVEL DRUG DELIVERY SYSTEM
Drug delivery via the oral mucous membrane is considered to be a promising alternative to the oral route. Sublingual dosage form is to be placed under the tongue and produce immediate systemic effect of enabling the drug absorbed directly through the mucosal lining of the mouth beneath the tongue which is very rich to vascular blood supply. Sublingual spray is useful when rapid onset of action is ...
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2087
DETECTION OF SILDENAFIL CITRATE FROM APHRODISIAC HERBAL FORMULATIONS
Sildenafil, the active ingredient in Viagra (Pfizer), is a prescription medicine used for erectile dysfunction. Sildenafil were isolated and purified during the analysis of some herbal products marketed for treatment of erectile dysfunction. There is no standardization technique for herbal formulations hence the addition of adulterants in herbal is very difficult to get hold of. Most of the adulte...
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2518
CHEMICAL COMPOSITION AND ANTI-INFLAMMATORY ACTIVITY OF ESSENTIAL OILS FROM THE LEAVES OF OCIMUM BASILICUM L. AND OCIMUM GRATISSIMUM L. (LAMIACEAE)
Ocimum basilicum L. and Ocimum gratissimum L. (Lamiaceae) are widely distributed aromatic herbs used in ethnomedicinal management of a range of inflammatory disorders. In the present work we evaluated the topical anti-inflammatory effects of the volatile constituents extracted from the fresh leaves of these plant species. Fresh leaves of the plants were subjected to hydro distillation to obtain th...
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2098
CHRONOTHERAPY: A REVIEW
Chronotherapy refers to the use of circadian, ultradian, infradian & seasonal or other rhythmic cycles in the application of therapy. There are number of conditions which show a circadian pattern and advantage could be taken by timing and adjusting the administration of drugs according to the circadian rhythm of the disease. Some of the conditions, which may be significantly benefited, are hyp...
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2293
ANTIBACTERIAL ACTIVITY OF MIXTURE OF LEAF EXTRACTS OF NEEM (AZADIRACHTA INDICA LINN.) AND TANTANI (LANTANA CAMARA)
Screening of medicinal plants for their antimicrobial activity leads to development of less expensive formulations with better safety and efficacy. A. indica and L. camara shows antibacterial activity. A. indica is multipurpose tree with wide range of uses. Also the L. camara has steroidal content showing cardiotonic, antispasmodic activity along with antibacterial activity. In the present study w...
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ROUTINE BLEEDING TECHNIQUES IN LABORATORY RODENTS
Collecting blood from Lab animals is necessary for a wide variety of scientific studies, and there are a number of efficient methods available. It is important to remember that blood collection can stress the animals, and may have an impact on the outcome of research data. Potential adverse affects viz. Hypovolemic shock, anemia, stress, haemorrhage, bruising, thrombosis; infection at the site of...
9459
1931
THERAPEUTIC POTENTIALS OF COW DERIVED PRODUCTS- A REVIEW
Kamdhenu or Indian cow (Bos indicus) is worshipped as sacred animal by Hindus. The reason for worshipping is the tremendous therapeutic values of cow derived products like cow milk, cow milk curd, cow butter (ghee), cow urine, cow dung and a combination formulation Panchgavya. The use of these products has been well defined in ancient Ayurvedic texts like Charak samhita, Shushruta samhita, Brahad-...
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TOTAL ANTIOXIDANT CAPACITY IN AQUEOUS EXTRACTS OF SOME COMMON FRUITS
The present study was aimed to evaluate total antioxidant capacities of eleven different commonly consumed aqueous fruit extracts viz. Ananas comosus, Artocarpus heterophyllus, Carica papaya, Citrullus vulgaris, Citrus sinensis, Malus domestica, Manilkara zapota, Musa paradisiaca, Phyllanthus emblica, Psidium guajava and Pyrus communis. The total antioxidant capacity was assessed using phosphomoly...
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1043
ANTI-BACTERIAL EFFICACY OF OCTENIDINE AS A MOUTH WASH
To evaluate the antimicrobial activity of Octenidine (OCT) 0.1%, Chlorhexidine (CHX) 0.2% against bacterial strains of Enterococcus faecalis and Staphylococcus aureus. The strains were inoculated in 7ml of brain heart infusion broth and diluted to reach the concentration equivalent (0.5 McFarland standard). 1ml of organism suspension was contacted with 1ml of each mouthwash and was removed at time...
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2382
NOVEL APPROACH: MICROSPONGE DRUG DELIVERY SYSTEM
Transdermal drug delivery system (TDS) is not practically for delivery of materials whose final target is skin itself. Application topical agents generally offer many problems such as rashes, skin irritancy and burning sensation etc due to higher percutaneous absorption of drugs on the skin. Some conventional dosage e.g., gels and ointments which are often aesthetically unappealing, greasiness and...
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