Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
ALLIUM SATIVUM REGULATES LIPID METABOLISM IN ALLOXAN INDUCED DIABETIC RATS
Allium sativum (A. sativum), commonly known as garlic, is a species in the onion genus, Allium. The hypolipidemic activity of A. Sativum (Family: Amaryllidaceae) extract have been studied in alloxan-induced diabetic rats. In this model oral administration of extract (500mg/kg bw., p.o.) for 15 days in diabetic-dyslipidemic rats exerted significant lipid lowering effect as assessed by the reversal ...
4080
2301
PROTECTIVE PROFILE OF HYDNOCARPUS LAURIFOLIA ON STREPTOZOTOCIN INDUCED OXIDATIVE STRESS IN RATS
The present study was aimed to evaluate the anti-oxidative defence system of Hydnocarpus laurifolia in diabetic rats and its potential effect against the β-cell damage induced by oxidative stress. Hydnocarpus laurifolia is a plant which belongs to the family Flacourtiaceae. According to the Indian system of traditional medicine it is used in the treatment of diabetes mellitus. Also literature rev...
3943
1553
DEVELOPMENT AND IN VITRO EVALUATION OF SUSTAINED RELEASE MATRIX TABLETS OF DICLOFENAC SODIUM USING DIFFERENT GRADE HYDROPHILIC POLYMER & PEG 6000 AS RELEASE RETARDANT
Diclofenac Sodium, being NSAID, its oral administration restricted due to its inherent problems. Hence in the present study, attempt has been made to design oral sustained release once daily matrix tablets of Diclofenac Sodium using combination of hydroxyl propyl methyl cellulose (HPMC) & PEG 6000 and to study the effect of various process and formulation variables like polymer properties and ...
4629
1991
SONOPHORETIC TRANSDERMAL DELIVERY OF LOSARTAN POTASSIUM PRONIOSOMAL GEL
Proniosomes based drug delivery systems have potential as a significant drug carrier in a variety of therapeutic applications. The objective of the present study was to investigate in vitro sonophoretic transdermal delivery of Losartan Potassium (LP) across albino rat skin using proniosomal gel and its comparison with aquasonic gel. Proniosomes of LP were fabricated with L-a-lecithin (egg yolk), c...
4386
1675
STATUS OF SERUM FRUCTOSAMINE IN HYPERTHYROID SUBJECTS IN UDAIPUR, RAJASTHAN
Introduction: Measurement of glycated hemoglobin (HbA1c) and fructosamine has a growing role in the assessment of glycemic control but their use for screening purpose is questionable. Material and methods: The study was carried out on 50 controls and 50 patients suffering from hyperthyroidism from October 2014 to March 2015 at Geetanjali Medical College & Hospital, Udaipur (Rajasthan). Results...
4251
2837
A PROMISING ANTINEOPLASTIC DRUG – METFORMIN (AN AMPK ACTIVATOR) FOR THE FUTURE
Metformin, an AMPK activator, acts as an oral hypoglycaemic agent. It reduces the risk of cancer during the treatment of diabetes and diabetes associated cancers. The effect of metformin on different type of cancers is explained on the pathway of AMPK activation involving hepatic fatty acid oxidation, inhibition of triglyceride and cholesterol synthesis and also modulation of insulin secretion. Th...
5575
1769
HIGH BODY MASS INDEX AND REDUCTION OF RESPONSE TO RITUXIMAB IN PATIENTS WITH RHEUMATOID ARTHRITIS
Adipose tissue has immunomodulating effects in rheumatoid arthritis (RA). Previous studies suggested that obesity could negatively affect the response to anti-TNF-α agents. We aimed to determine whether body mass index (BMI) is involved in the response to the anti-CD20 "Rituximab" in RA. In 100 patients with active RA, the BMI was categorized into two groups (<25 kg/m2 and ≥ 25 kg/m2) and ca...
4523
1576
PHARMACOLOGICAL EFFICACY OF METHANOLIC EXTRACT OF THE PLANT GINKGO BILOBA, AGAINST ISOPROTERENOL INDUCED CARDIAC TOXICITY IN RATS
Ginkgo Biloba is a potent antioxidant dietary source for human health. Oxidative stress through generation of free radicals damages the myocardium in different experimental condition. The present research was designed to evaluate the cardio protective role of chronic oral administration of Ginkgo biloba leaf extract against Isoproterenol induced myocardial injury. Male Wistar albino rates were ran...
4049
1675
ANTI-DIABETIC ACTIVITY OF ETHANOL EXTRACT OF PRAECITRULLUS FISTULOSUS LEAVES ON STREPTOZOTOCIN INDUCED DIABETIC RATS
Objective: The present study was designed to evaluate the anti-diabetic activity of ethanol extract of Praecitrullus fistulosus leaves on streptozotocin induced diabetic rats. Materials and Methods: The anti-diabetic activity of plant leaves was investigated in streptozotocin induced diabetes model. Effect of ethanol extract of Praecitrullus fistulosus (EPF) leaves on normal blood glucose levels a...
5437
1942
FORMULATION AND EVALUTION OF LANSOPRAZOLE ORODISPERSABLE TABLETS
Lansoprazole a proton pump inhibitor used in the short term treatment of gastric and duodenal ulcer, reflux esophagitis, structuring and erosive esophagitis. In the present investigation an attempt has been made to enhance the solubility and dissolution rate of lansprozole by formulating it as solid dispersions with KollidonVA64, Soluplus and poly ethylene glycol 6000 by solvent evaporation method...
6688
2630