Most Cited
| Year | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 | Total |
|---|---|---|---|---|---|---|---|
| No. of Published Articles | 745 | 760 | 549 | 628 | 408 | 376 | 3466 |
| Citations | 2186 | 1048 | 351 | 329 | 66 | 6 | 3986 |
| Projected Impact Factor | 6.64 | 4.43 | 2.15 | 1.07 | 0.58 | 0.38 |
LIFE CYCLE APPROACH TO CLEANING VALIDATION
The regulatory expectations are changing day by day on the cleaning validation in Pharmaceutical industries, considering the patient safety and drug efficacy. Manufacturing of an Intermediate and Active Ingredient Pharmaceuticals involves many chemical syntheses and same equipment is being using for manufacturing of different product in multi-production facility. Equipment cleaning plays a key rol...
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IMPORTANCE OF SR-B1 RECEPTOR IN CARCINOGENESIS AND TREATMENT: A REVIEW
Scavenger receptor class B member 1 also known as SR-B1 is a receptor that in human is encoded by the SCARB1 gene. SR-B1 functions as a receptor for high density lipoprotein. SR-B1 receptor is mostly found in liver and is best known for its role in facilitating the uptake of cholesteryl ester from HDL in liver. This movement of cholesterol is known as reverse cholesterol transport. Cancerous cells...
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AMELIORATIVE EFFECT OF HELIX ASPERSA CRUDE EXTRACT AGAINST COLONIC DAMAGES INDUCED BY HYPERHOMOCYSTEINEMIA IN RATS
The present study was designed to evaluate the effect of Helix aspersa crude extract on colonic injury resulting from hyperhomocysteinemia induced by feeding rats high methionine diet. Wistar albino rats (200-250g) were divided into four groups. Hyperhomocysteinemia (Hhcy) was induced by methionine treatment (1g/kg/day) for 15 days. M group received only Methionine, MH and MP received Methionine a...
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SCIENTIFIC VALIDATION ON SIDDHA PURIFICATION PROCESS OF NABHI
Suddhi is a unique process of detoxification which is employed topotentiate as well as enhance therapeutic properties the effect of raw drugs. Nabhi (Aconitum ferox), a herbal poisonous rhizome commonly known as aconitum is used extensively in various Siddha formulations, with great therapeutic significance. Siddha system recommends the administration of Nabhi only after suddhi (purification) in...
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IN-VITRO STUDY OF AMLODIPINE AND NIFEDIPINE DRUGS OF PULSATILE DRUG DELIVERY SYSTEM
To develop pulsatile microspheres of amlodipine and nifedipine drug release, a blend of polymer and solvent were used with pulsatile principles of drug delivery system to modified drug release pattern on and to release the drug at a particular time on the basis of lag time. In this study, we assessed the in vitro drug release pattern of the formulation prepared from different polymers ratio with t...
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SIMULTANEOUS DETERMINATION OF ETODOLAC AND PARACETAMOL IN BULK DRUGS AND PHARMACEUTICAL FORMULATION BY HPTLC-DENSITOMETRIC AND UV-DERIVATIVE SPECTROPHOTOMETRY METHODS
In current research work two methods have been developed for simultaneous determination of etodolac and paracetamol in binary mixtures. HPTLC-densitometry was employed for the determination of the mixture for etodolac 50-400 ng band⁻¹ and for paracetamol 50-300 ng band⁻¹. Separation was carried out on a silica gel 60 F254 HPTLC plates, using toluene: acetone: methanol: glacial acetic acid (6...
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EVOLVULUS ALSINOIDES (EAE) PLANT EXTRACT AS A MODULATOR OF CHOLINERGIC SYSTEM WITH REFERENCE TO ALZHEIMER’S DISEASE
Alzheimer’s disease is a form of dementia, in which nerve cells in memory areas of brain and eventually other areas begin to die at accelerated rate resulting in serious deterioration in several mental functions such as memory loss, language, orientation and judgment. The main objective of the present study was to investigate and compare the neuro-pharmacological effects of Evolvulus alsinoides ...
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A RANDOMIZED CLINICAL TRIAL TO ASSESS AND COMPARE THE ANTIMICROBIAL ACTIVITY OF PLANTS OF LYTHRACEAE FAMILY WITH HIORA MOUTH WASHES IN SUBJECTS WITH CHRONIC PERIODONTITIS – “UNVEILING THE UNSEEN EFFECTS”
Aims and objectives: Periodontal disease is the most common disease associated with microbial infection with destruction of supporting structures. The aim of the present study is compare the antimicrobial efficacy of plants of lythraceae family with hiora mouthwash in subjects with chronic periodontitis. Materials and methods: A total of 90 subjects were taken and randomly divided into three group...
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A PROSPECTIVE STUDY TO COMPARE THE EFFECT OF DIFFERENT HAART REGIMENS ON CD4 COUNTS OF HIV PATIENTS WITH TUBERCULOSIS
Introduction: AIDS is one the most dreaded diseases of human race in the present times. More than two- third of HIV infected individuals have an associated infectious pulmonary disease. Mycobacterium tuberculosis is considered as more virulent compared to other opportunistic pathogen causing latent infection. Cure of AIDS is still an unsolved mystery but some of the drugs have been developed to de...
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IMPACT OF DIFFERENT CARBON SUPPLEMENT ON EXTRACTION OF C-PHYCOCYANIN (C-PC) FOLLOWED BY POLY-β-HYDROXYBUTYRATE (PHB) FROM NOSTOC MUSCORUM
The extraction of poly-β-hydroxybutyrate (PHB) and C-phycocyanin (C-PC) from Nostoc muscorum revealed that PHB yield after C-PC extraction was not found differ significantly as without C-PC extraction. Under photoautotrophic growth condition, the test cyanobacterium accumulates PHB and C-PC with a maximum yield of 40 and 57 mg l-1 respectively at the stationary phase, i.e. on day 21 of incubation...
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